Method for producing suppository for treating uterus adenomyosis

Abstract

A preparation method of suppository for treating uterine adenomyosis mainly solves the problem of suppository material source and product cost. the preparation method comprises (1) cutting aseptic gelatin sponge into thin slices, overlaying, scissoring one end of the sponge into multiple filaments, scissoring into fine particle until to the other end of the sponge, packaging, sterilizing with oxirane, and standing for 2 weeks; (2) dissolving Pingyangmycin 24 mg in physiological saline for operation; and (3) inserting the conduit into one side of the uterine artery, putting the gelatin sponge into a 20mL disposable syringe, decimating the Pingyangmycin physiological saline solution repeatedly, and injecting with the conduit. The method has the advantages of easily-accessible raw materials, low cost, and high security.

Description

technical field

[0001] The invention relates to a method for making a medical embolism, in particular to a method for making an embolism for treating adenomyosis. technical background

[0002] Adenomyosis is a disease caused by endometrium intrusion into the uterine muscular wall. It is a special type of endometriosis. In the past, sex hormones or surgery were often used for treatment. However, the side effects of sex hormones are significant, the surgical trauma is huge, and some patients also lose their fertility. In recent years, American scholars pioneered uterine artery embolization to treat this disease, with mild trauma and side effects and satisfactory curative effect. Soon, this technology was promoted in many large and medium-sized hospitals at home and abroad. However, the embolic agents used in foreign and domestic hospitals are all polyvinyl alcohol (PVA) produced abroad. In recent years, sodium alginate particles have also been developed in China and used in ...

Examples

Embodiment Construction

[0026] The embolic agent consists of gelatin sponge particles and pingyangmycin saline.

[0027] The embolism preparation method for the treatment of adenomyosis, the steps are as follows:

[0028] 1) Take a piece of sterile gelatin sponge with a length of 60mm, a width of 20cm, and a thickness of 6mm, cut it into four slices with a thickness of about 1.5mm on average with a razor blade, stack the slices, align them with each other and pinch them as much as possible Then use scissors to cut a section of the sponge block into multiple filaments from one end, and then cut the filaments horizontally into fine particles; Near the other end of the block, discard the part that can no longer be cut; wrap the cut particles with 128K white paper, seal in a plastic bag, sterilize with ethylene oxide, and store it for 2 weeks before use;

[0029] In principle, the thinner the hand-cut gelatin sponge filaments, the better, and the smaller the transversely cut particles, the better. If t...

technical field

[0001] The invention relates to a method for making a medical embolism, in particular to a method for making an embolism for treating adenomyosis. technical background

[0002] Adenomyosis is a disease caused by endometrium intrusion into the uterine muscular wall. It is a special type of endometriosis. In the past, sex hormones or surgery were often used for treatment. However, the side effects of sex hormones are significant, the surgical trauma is huge, and some patients also lose their fertility. In recent years, American scholars pioneered uterine artery embolization to treat this disease, with mild trauma and side effects and satisfactory curative effect. Soon, this technology was promoted in many large and medium-sized hospitals at home and abroad. However, the embolic agents used in foreign and domestic hospitals are all polyvinyl alcohol (PVA) produced abroad. In recent years, sodium alginate particles have also been developed in China and used in ...

Examples

Embodiment Construction

[0026] The embolic agent consists of gelatin sponge particles and pingyangmycin saline.

[0027] The embolism preparation method for the treatment of adenomyosis, the steps are as follows:

[0028] 1) Take a piece of sterile gelatin sponge with a length of 60mm, a width of 20cm, and a thickness of 6mm, cut it into four slices with a thickness of about 1.5mm on average with a razor blade, stack the slices, align them with each other and pinch them as much as possible Then use scissors to cut a section of the sponge block into multiple filaments from one end, and then cut the filaments horizontally into fine particles; Near the other end of the block, discard the part that can no longer be cut; wrap the cut particles with 128K white paper, seal in a plastic bag, sterilize with ethylene oxide, and store it for 2 weeks before use;

[0029] In principle, the thinner the hand-cut gelatin sponge filaments, the better, and the smaller the transversely cut particles, the better. If t...