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Medicinal composition for treating impaired glucose tolerance and preparation method thereof

A technology of abnormal glucose tolerance and composition, which is applied in the field of pharmaceutical composition for the treatment of abnormal glucose tolerance, can solve problems such as hypoglycemia and patient difficulty, and achieve the effect of lowering blood sugar, definite curative effect, and unique composition

Active Publication Date: 2007-10-17
ZHONGSHI TAILING BEIJING BIO SCI & TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the existing chemical drugs for the treatment of diabetes, such as sulfonylureas, insulin sensitizers, metformin, and α-glucosidase inhibitors, can be used to treat abnormal glucose tolerance, they can easily lead to hypoglycemia, which is unbearable for ordinary patients.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0107] Weigh the raw materials according to the following proportions: 8 parts of dried bitter gourd, 2 parts of mulberry leaves, 1 part of Panax notoginseng, 2 parts of Ligustrum lucidum, 2 parts of Gynostemma pentaphyllum, 0.001 part of chromium picolinate, 0.01 part of zinc gluconate, 0.3 part of dextrin, Magnesium stearate 0.01 part.

[0108] Preparation:

[0109] (1) Alcohol extraction: take the formula amount of Panax notoginseng and put it in a universal pulverizer and pulverize it into 8-10 mesh coarse powder for later use; take the formula amount of dried bitter gourd, Ligustrum lucidum, Gynostemma japonica qualified decoction pieces and Panax notoginseng coarse powder and put them into multi-functional extraction In the tank, use 6-10 times the amount of 60-80% ethanol to heat and extract for 1.5 hours, filter the extract with a 120-mesh stainless steel sieve, add 6-8 times the amount of 60-80% to the residue for heating and extract for 1.5 hours, and use 120 Filter...

Embodiment 2

[0115] Weigh the raw materials according to the following proportions: 28 parts of dried bitter gourd, 8 parts of mulberry leaves, 5 parts of Panax notoginseng, 8 parts of Ligustrum lucidum, 8 parts of Gynostemma pentaphyllum, 0.006 part of chromium picolinate, 0.1 part of zinc gluconate, 1 part of dextrin, Magnesium stearate 0.08 part.

[0116] Preparation:

[0117] (1) Alcohol extraction: take the formula amount of Panax notoginseng and put it in a universal pulverizer and pulverize it into 8-10 mesh coarse powder for later use; take the formula amount of dried bitter gourd, Ligustrum lucidum, Gynostemma japonica qualified decoction pieces and Panax notoginseng coarse powder and put them into multi-functional extraction In the tank, use 6-10 times the amount of 60-80% ethanol to heat and extract for 1.5 hours, filter the extract with a 120-mesh stainless steel sieve, add 6-8 times the amount of 60-80% to the residue for heating and extract for 1.5 hours, and use 120 Filter ...

Embodiment 3

[0123] Weigh the raw materials according to the following proportions: 16.7 parts of dried bitter gourd, 3.3 parts of mulberry leaves, 2.2 parts of Panax notoginseng, 3.3 parts of Ligustrum lucidum, 3.3 parts of Gynostemma pentaphyllum, 0.002 part of chromium picolinate, 0.07 part of zinc gluconate, 0.52 part of dextrin, Magnesium stearate 0.02 part.

[0124] Preparation:

[0125] (1) Alcohol extraction: take the formula amount of Panax notoginseng and put it in a universal pulverizer and pulverize it into 8-10 mesh coarse powder for later use; take the formula amount of dried bitter gourd, Ligustrum lucidum, Gynostemma japonica qualified decoction pieces and Panax notoginseng coarse powder and put them into multi-functional extraction In the tank, use 6-10 times the amount of 60-80% ethanol to heat and extract for 1.5 hours, filter the extract with a 120-mesh stainless steel sieve, add 6-8 times the amount of 60-80% to the residue for heating and extract for 1.5 hours, and us...

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PUM

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Abstract

The invention relates to a medicine combination for treating the impaired glucose tolerance and the preparing method thereof. The medicine combination is mainly composed of balsam pear, mulberry leaf, sanchi, glossy privet fruit, fiveleaf gynostemma herb, chromium picolinate, and zinc gluconate. It is a preparation produced by pharmacological acceptable carrier or excipient, containing capsule, granule, tablet, soft capsule, dropping pill and etc, which is suitable for the patent with impaired glucose tolerance and forepart diabetes. The research indicates that the invention can reduce the blood sugar, decline the insulin resistance, enhance the insulin sensitivity, protect the beta cell function, reduce the serum total cholesterol and serum triglyceride without side and poisonous effects.

Description

1. Technical field [0001] The invention relates to a pharmaceutical composition for treating abnormal glucose tolerance and a preparation method thereof. 2. Background technology [0002] Impaired glucose tolerance (IGT) refers to an intermediate state in which a patient's blood sugar is between normal blood sugar levels and diabetic blood sugar levels. It is generally recognized that IGT is a pre-diabetes stage and a dangerous stage for developing diabetes. With the improvement of people's living standards, the prevalence of impaired glucose tolerance has increased significantly. WHO announced in 1993 that the prevalence of IGT in adults aged 30 to 64 in the world is mostly 3.0% to 10.0%. In the 1996 National Diabetes Epidemiological Survey, the standardized prevalence of IGT was 5.78% in provincial capitals and 3.14% in poor counties and townships. my country has a population of 1.3 billion. If the prevalence of IGT is calculated at an average of 4.46%, the number of pa...

Claims

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Application Information

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IPC IPC(8): A61K36/605A61K31/704A61K9/16A61K9/20A61K9/48A61P3/10A61K31/191A61K31/455
Inventor 刘铜华
Owner ZHONGSHI TAILING BEIJING BIO SCI & TECH
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