Preparation method for effective drug capsule for gastric disease

A Weikangling Capsule, the purpose of the technology, applied in the direction of capsule delivery, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems that are not given, and achieve the effect of improving powder characteristics and reducing the difference in loading volume

Inactive Publication Date: 2007-10-17
杨文龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the specific preparation process on page 518 of the 2005 edition of the Chinese Pharmacopoeia (Part One), the specific crushing particle size of Baiji, Panax notoginseng, and squid octopus is not given, and the crushing particle size of the whole medicinal material in traditional Chinese medicine is a key parameter. It is related to the uniformity of various ingredients in the compound drug and the difference in the filling capacity of the capsules

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Prescription Baiji 238.1g Radix Paeoniae Alba 317.5g

[0020] Notoginseng 9.9g Licorice 317.2g

[0021] Poria cocos 238.1g Corydalis 158.7g

[0022] Sea Cuttlefish 31.7g Belladonna Extract 2.1g

[0023] Preparation method: the above Bawei, Baiji and Panax notoginseng are crushed into a fine powder with a particle size of 90 mesh, and the squid octopus is crushed into a fine powder with a particle size of 100 mesh; licorice is decocted with water for four times, the first and second times are 3 hours each, and the third is , four times each for 2 hours, filter the decoction, combine the filtrates, let it stand for 24 hours, take the supernatant, and set aside; add water to decoct the white peony root, Corydalis Corydalis, and Poria cocos for two times, the first time is 3 hours, and the second time is 2 hours , filter the decoction, combine the filtrates, let stand for 24 hours, take the supernatant, combine with the above supernatant, concentrate to ...

Embodiment 2

[0025] Prescription Baiji 238.1g Radix Paeoniae Alba 317.5g

[0026] Notoginseng 9.9g Licorice 317.2g

[0027] Poria cocos 238.1g Corydalis 158.7g

[0028] Sea Cuttlefish 31.7g Belladonna Extract 2.1g

[0029] Preparation method: the above Bawei, Baiji and Panax notoginseng are crushed into a fine powder with a particle size of 90 mesh, and the squid octopus is crushed into a fine powder with a particle size of 150 mesh; licorice is decocted with water for four times, the first and second times are 3 hours each, and the third , four times each for 2 hours, filter the decoction, combine the filtrates, let it stand for 24 hours, take the supernatant, and set aside; add water to decoct the white peony root, Corydalis Corydalis, and Poria cocos for two times, the first time is 3 hours, and the second time is 2 hours , filter the decoction, combine the filtrates, let stand for 24 hours, take the supernatant, combine with the above supernatant, concentrate to an ...

Embodiment 3

[0031] Prescription Baiji 238.1g Radix Paeoniae Alba 317.5g

[0032] Notoginseng 9.9g Licorice 317.2g

[0033] Poria cocos 238.1g Corydalis 158.7g

[0034] Sea Cuttlefish 31.7g Belladonna Extract 2.1g

[0035] Preparation method: the above Bawei, Baiji and Panax notoginseng are crushed into a fine powder with a particle size of 100 mesh, and the squid octopus is crushed into a fine powder with a particle size of 150 mesh; licorice is decocted with water for four times, the first and second times are 3 hours each, and the third , four times each for 2 hours, filter the decoction, combine the filtrates, let it stand for 24 hours, take the supernatant, and set aside; add water to decoct the white peony root, Corydalis Corydalis, and Poria cocos for two times, the first time is 3 hours, and the second time is 2 hours , filter the decoction, combine the filtrates, let stand for 24 hours, take the supernatant, combine with the above supernatant, concentrate to an...

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PUM

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Abstract

Disclosed is a method for preparing 'Wei Kang Ling' capsule which consists of white peony root 317.5g, hyacinth bletilla 238.1g, notoginseng 9.9g, licorice 317.2g, poria 238.1g, corydalis tuber 158.7g and cuttlebone 31.7g, belladonna 2.1g and medicinal adjuvant. The invention improves the powder property of capsule content and reduces the difference of loading capacity by modifying the process.

Description

【Technical field】 [0001] The invention belongs to the technical field of pharmaceutical preparations, and in particular relates to a preparation method of Weikangling capsules. 【Background technique】 [0002] Weikangling Capsule is based on the anti-ulcer effect of Shaoyao Gancao Decoction in the famous Chinese medicine book "Treatise on Febrile Diseases". A good medicine for stomach problems. Weikangling has the functions of antispasmodic, analgesic, hemostatic, antacid, comprehensive repair of gastric mucosa, elimination of ulcer and inflammation of surrounding tissues. This product is hard capsule, the content is light yellow to brown powder; sweet in taste. [0003] Weikangling Capsule softens the liver and harmonizes the stomach, dispels blood stasis and stops bleeding, relieves spasms and relieves pain, removes putrefaction and promotes regeneration. For liver-stomach disharmony, stagnant blood stasis caused by gastritis pain, joints and flanks, belching, pantotheni...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/48A61P1/04A61K35/56A61K35/618
Inventor 杨文龙
Owner 杨文龙
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