Method for treating coronary heart disease and angina pectoris

A coronary heart disease angina pectoris and drug technology, applied in the field of medicine, to achieve significant drug effects, uniform and stable drug quality, and reduce the size of myocardial infarction

Inactive Publication Date: 2008-02-13
SHANDONG XUANZHU PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] At present, there is no report on the use of the interaction and compatibility of Trichosanthes, Curcuma, Shichangpu and Danshen to prepare medicines for treating angina pectoris of coronary heart disease.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Embodiment 1: the preparation of pharmaceutical tablet of the present invention

[0067] Gualou 450g Turmeric 300g Shichangpu 300g Salvia 450g

[0068] Weigh the trichosanthes, turmeric, calamus and salvia miltiorrhiza in said parts by weight; extract the weighed turmeric with 6 times the amount of water by steam distillation for 8 hours, collect the water extract, and use β-cyclodextrin for the volatile oil Inclusion (dissolve β-cyclodextrin in an appropriate amount of water to make a saturated solution, inject volatile oil, stir at high speed for 2 hours, refrigerate for 24 hours, and filter), dry the inclusion at 60°C; Ethanol reflux extraction twice, first add 8 times the amount of alcohol, reflux for 2 hours, add 6 times the amount of alcohol for the second time, reflux for 1 hour, combine the extracts, filter, and recover the ethanol from the filtrate until it has no alcohol smell and concentrate to a thick paste; decoct the weighed medicinal dregs of Trichosan...

Embodiment 2

[0069] Embodiment 2: the preparation of medicine capsule of the present invention

[0070] Gualou 450g Turmeric 300g Shichangpu 300g Salvia 450g

[0071]Weigh the trichosanthes, turmeric, calamus and salvia miltiorrhiza in said parts by weight; extract the weighed turmeric with 6 times the amount of water by steam distillation for 8 hours, collect the water extract, and use β-cyclodextrin for the volatile oil Inclusion (dissolve β-cyclodextrin in an appropriate amount of water to make a saturated solution, inject volatile oil, stir at high speed for 2 hours, refrigerate for 24 hours, and filter), dry the inclusion at 60°C; Ethanol reflux extraction twice, first add 8 times the amount of alcohol, reflux for 2 hours, add 6 times the amount of alcohol for the second time, reflux for 1 hour, combine the extracts, filter, and recover the ethanol from the filtrate until it has no alcohol smell and concentrate to a thick paste; decoct the weighed medicinal dregs of Trichosanthes T...

Embodiment 3

[0072] Embodiment 3: the preparation of pharmaceutical granule of the present invention

[0073] Gualou 450g Turmeric 300g Shichangpu 300g Salvia 450g

[0074] Weigh the trichosanthes, turmeric, calamus and salvia miltiorrhiza in said parts by weight; extract the weighed turmeric with 6 times the amount of water by steam distillation for 8 hours, collect the water extract, and use β-cyclodextrin for the volatile oil Inclusion (dissolve β-cyclodextrin in an appropriate amount of water to make a saturated solution, inject volatile oil, stir at high speed for 2 hours, refrigerate for 24 hours, and filter), dry the inclusion at 60°C; Ethanol reflux extraction twice, first add 8 times the amount of alcohol, reflux for 2 hours, add 6 times the amount of alcohol for the second time, reflux for 1 hour, combine the extracts, filter, and recover the ethanol from the filtrate until it has no alcohol smell and concentrate to a thick paste; decoct the weighed medicinal dregs of Trichosa...

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PUM

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Abstract

The present invention belongs to the medicine technical field and discloses a medicine used for curing an angina of coronary heart disease and a preparation method of the medicine. The medicine is prepared by a snakegrourd fruit, a turmeric root tuber, a grassleaf sweetflag rhizome and a danshen root according to certain weight compounding ratio. The medicine can be made as any acceptable clinical or pharmacological dose form, and an oral preparation is preferential. The medicine has efficacies of regulating qi and relieving a chest, eliminating turbidity and dispersing depressed qi and removing blood stasis and dredging channels, and the medicine is applicable to the angina of coronary heart disease with symptoms of oppression and pain in the chest, cough and rapid breathing, palpitation and shortness of breath and spiritlessness and unwillingness to talk.

Description

1. Technical field [0001] The invention belongs to the technical field of medicine and relates to a medicine for coronary heart disease angina pectoris, in particular to a medicine for coronary heart disease angina pectoris made from Chinese herbal medicine. 2. Background technology [0002] Coronary heart disease angina pectoris is a common type of coronary heart disease caused by paroxysmal pain or discomfort in the chest caused by coronary atherosclerosis leading to lumen stenosis or coronary artery spasm, myocardial ischemia and hypoxia. In recent years, the incidence of coronary heart disease angina pectoris has increased significantly, and its proportion in heart disease has jumped to the first place. [0003] The main causes of this disease are long-term improper diet, old age, physical weakness, internal invasion of cold pathogens, and emotional disorders, which are mostly proximate causes or inducements. Excessive physical or mental work, on the basis of insufficie...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P9/10
Inventor 黄振华
Owner SHANDONG XUANZHU PHARMA TECH CO LTD
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