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Ruheneixiao granules and method for preparing the same

A technology of Ruhei and granules, which is applied in the field of Ruhe Neixiao Granules and its preparation for the treatment of Ruhei and Rupi. It can solve the problems of turbidity of the medicine liquid, difficult acceptance by patients, and difficulty in quality control, so as to ensure extraction and utilization, Avoid the loss of active ingredients and improve the effect of purity

Active Publication Date: 2008-04-02
TIANJIN PHARMA GROUP XINZHENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine often uses sex hormones and surgical treatment, but the side effects are very large, which is not easily accepted by patients
The "nucleus internal elimination liquid" sold in the market is only boiled into decoction according to the ancient recipe. The liquid is turbid, not easy to carry, difficult to store, easy to mildew, and difficult to control the quality, which does not meet the international requirements of traditional Chinese medicine products.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Example 1. Ruhe Neixiao Granules and its preparation method. Take 87.5 parts of dry and clean Angelica sinensis, 75 parts of Cyperus rotundus, 125 parts of Bupleurum and 125 parts of turmeric (Chinese medicine decoction pieces) and add 4 times water according to weight parts. Soak for 1h and extract volatile oil for 4h. The dregs and liquid medicine, 150 parts of Fritillaria vulgaris, 150 parts of red peony root, 87.5 parts of locust, 150 parts of madder, 75 parts of orange core, 125 parts of prunella vulgaris, 37.5 parts of loofah, and 18.75 parts of licorice are decocted twice in water. Add water to 8 times the amount for the first time, add 6 times the amount of water for the second time, 1.5 hours each time. The filtrate was concentrated to a relative density of 1.04-1.05 (60°C), and then added to the alcohol precipitation tank with 4 times the weight percentage of 95% ethanol and allowed to stand for 24 hours. The supernatant was concentrated to obtain a clear ointment...

Embodiment 2

[0025] Example 2. In this example, the parts by weight of the medicinal materials are: 165 parts of Fritillaria fritillariae, 96 parts of Angelica, 165 parts of Red Peony Root, 96 parts of Oleus vulgaris, 165 parts of Rubia, 83 parts of Cyperus rotundus, 140 parts of Bupleurum and Citrus 83 parts of core, 140 parts of prunella, 41 parts of loofah, 140 parts of turmeric, 20 parts of licorice. The weight of powdered sugar is 92 parts, the weight of dextrin is 850 parts, and the steviol accounts for 0.5‰ of the total weight.

[0026] In the volatile oil extraction step, add 3 times of water, soak for 1.5 hours, and extract the volatile oil for 3 hours. The steps of extracting dry ointment by decoction of traditional Chinese medicine are: the dregs and medicinal liquid of Angelica, Cyperus rotundus, Bupleurum turmeric and turmeric after the volatile oil is extracted, and fritillaria, red peony, rhizome, madder, orange nucleus, prunella vulgaris, loofah, licorice Add water to decoct tw...

Embodiment 3

[0028] Example 3. In this example, the parts by weight of the medicinal materials are: 180 parts of Fritillaria fritillariae, 105 parts of Angelica, 180 parts of Red Peony Root, 105 parts of Rhizoma Dioscoreae, 180 parts of Rubia, 90 parts of Cyperus rotundus, 150 parts of Bupleurum, Tangerine 90 parts of core, 150 parts of prunella, 45 parts of loofah, 150 parts of turmeric, 22.5 parts of licorice. The weight of powdered sugar is 103 parts, the weight of dextrin is 928 parts, and the stevioside accounts for 0.5‰ of the total weight.

[0029] In the volatile oil extraction step, add 5 times water, soak for 2 hours, and extract the volatile oil for 5 hours. The decoction steps of traditional Chinese medicine are: extract the volatile oil of Angelica sinensis, Cyperus rotundus, Bupleurum and turmeric dregs and medicinal liquid, fritillaria, red peony, louver, madder, orange core, prunella, loofah, licorice and decocting with water The second time, add water to 9 times the amount for...

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PUM

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Abstract

The invention relates to a nucleus internal dissolution grain and a method of preparing the grain. Dry and clean Chinese angelica, nutgrass galingale rhizome, Chinese thorowax root, turmeric root tuber are extracted to obtain ligroine for future use; decoction dreg, liquid medicine, fritillaria thunbergii, radix paeoniae rubra, uniflower swisscentaury root, gamene, tangerine seed, spicaprunellae, luffa and radix glycyrrhizae are added water and decocted; the filtrate is condensed and settled to obtain clear paste; icing sugar, dextrine and sweet principle are added into the clear paste to obtain a soft material, or the clear paste is sponging dried to obtain dry paste; the icing sugar, the dextrine, the sweet principle and an appropriate amount of bond are added into the dry paste to obtain the soft material; the soft material is made into wet grains, boiled and dried to obtain dry grains; the ligroine is sprayed in to obtain the nucleus internal dissolution grains; the weight portion of the medicinal materials are: 150 to 180 portion of fritillaria thunbergii, 87.5 to 105 portion of Chinese angelica, 150 to 180 portion of radix paeoniae rubra, 87.5 to 105 portion of uniflower swisscentaury root, 150 to 180 portion of gamene, 75 to 90 portion of nutgrass galingale rhizome, 125 to 150 portion of Chinese thorowax root, 75 to 90 portion of tangerine seed, 125 to 150 portion of spicaprunellae, 37.5 to 45 portion of luffa, 125 to 150 portion of turmeric root tuber and 18.75 to 22.5 portion of radix glycyrrhizae. The invention can effectively cure nucleus and breast lump.

Description

Technical field [0001] The invention belongs to the technical field of medical preparations, and in particular relates to a kind of Ruhei Neixiao granules for treating breast nucleus and breast addiction and a preparation method thereof. Background technique [0002] It is generally believed that hyperplasia of mammary glands is related to endocrine dysfunction. Excessive levels of estradiol and prolactin, or an increase in the ratio of estradiol to progesterone, lead to excessive growth of breast tissue or incomplete involution. Western medicine uses sex hormones and surgical treatments, but the side effects are very serious, which is not easy for patients to accept. The "nuclear internal digestion liquid" sold on the market only followed the ancient recipes to make decoctions, which are turbid, difficult to carry, difficult to store, easy to mold, and difficult to control quality, which does not meet the international requirements of traditional Chinese medicine products. Summ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/16A61P15/14
Inventor 陈智锋
Owner TIANJIN PHARMA GROUP XINZHENG