Pharmaceutical combination for curing acne as well as preparations and preparation thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating acne, its preparation method and its application. The composition comprises an active ingredient composed of nine medicines and a conventional pharmaceutical carrier, and the active ingredient is composed of the following ingredients : Salvia, Hedyotis diffusa, Pueraria, Angelica, Dandelion, Forsythia, Morus Alba, Loquat Leaf and Fritillaria. The composition of the present invention can be produced by conventional methods in the art, and can be made into various commonly used dosage forms, especially oral dosage forms, such as granules and the like. When the composition of the invention is used for clinical treatment of acne, it has remarkable curative effect and no toxic or side effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating acne, its preparation, its preparation method and application. The composition of the invention uses Chinese herbal medicine as the main raw material, and has remarkable curative effect and no toxic or side effect when it is clinically used for treating acne. Background technique [0002] Acne is a chronic inflammatory skin disease of the pilosebaceous gland structure, and its clinical manifestations include acne, papules, pustules, nodules, cysts and other types, and scar formation can be seen. Occurs in the face, neck and chest and back. Its etiology is complex and has not been fully understood so far. It is known that endocrine factors (especially androgen), microbial factors (mainly Propionibacterium acnes), abnormal sebaceous duct keratosis, immune factors, mental factors, genetic factors, etc. have played an important role in the pathogenesis of acne. The disease ...

AI Technical Summary

Problems solved by technology

For example, topical retinoic acid preparations are effective for mild and moderate acne, but poor for severe acne, and skin irritation is common; oral retinoic acid preparations can play a role in multiple links of acne, and the effect is satisfactory, but its systemic Side effects such as teratogenicity, dry skin and mucous membranes, abnormal blood lipid metabolism, bone abnormalities, liver function damage, and effects on muscles limit its wide clinical application; currently commonly used antibiotics are easy to take and have good curative effect on inflammatory skin lesions of acne. However, due to the long course of treatment (antibiotics need to be used continuously for at least 2 months), their adverse reactions and drug resistance are still issues that need attention, and all current antibiotics can only reduce but not completely eliminate Propionibacterium acnes; contraceptives only It is suitable for women of childbearing age who need contraception, and have side effects such as uterine bleeding, breast tenderness, upper abdominal discomfort, and redness of the facial skin; estrogen and anti-androgen therapy have many side effects, such as endocrine disorders, affecting male sexual function etc., recommended for women only and not suitable for routine therapy

[0007] Traditional Chinese medicine has obvious advantages in the treatment of this disease, but currently there are few Chinese patent medicines for acne treatment, the choice of clinical doctors is limited, and most of the functions of existing Chinese patent medicines are mainly heat-clearing and detoxifying, with a single effect and unsatisfactory effect

Traditional Chinese medicine decoction has good curative effect and few side effects, but the taste is poor, and it is inconvenient to decoct and take

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