Yanghe decoction oral formulations and preparation method thereof
An oral preparation, yang deficiency technology, applied in the field of medicine, can solve the problems of inconvenience in carrying and taking, inaccurate dosage, and inability to commercialize
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Embodiment 1
[0040] Embodiment one: Yanghe decoction extract (extract and volatile oil) preparation method
[0041] Prescription: 30 parts of rehmannia glutinosa, 6 parts of white mustard seeds, 9 parts of antler gum, 3 parts of cinnamon, 2 parts of ginger charcoal, 2 parts of ephedra, 3 parts of licorice
[0042] Preparation method: cleanly select the prescription medicinal materials, weigh each medicinal material according to the prescription amount, add 8 to 12 times the amount of water to soak for 2-10 hours, heat and boil for 2-3 times, combine the extracts, collect the volatile oil; water extraction The liquid was left to stand for 12-48 hours, filtered to get the supernatant, and concentrated under reduced pressure to obtain a medicinal extract of about 17.5 g of water extract and about 0.2 g of volatile oil.
Embodiment 2
[0043] Example 2: Preparation method of oral solid preparation of Yanghe Decoction
[0044] (1) Preparation of Yanghe Decoction Granules
[0045] prescription:
[0046] Yanghe Decoction Extract 10-90%
[0047] Starch 5.0-70%
[0048]Dextrin 2.0-20%
[0049] Xylitol 5.0-20%
[0050] Methyl sorbate 0.001-2.0%
[0051] Preferred Prescription:
[0052] Yanghe Decoction Extract 17.7g
[0053] Starch 8.0g
[0054] Dextrin 8.0g
[0055] Xylitol 4.0g
[0056] Methyl sorbate 0.002g
[0057] Preparation method: prepare the Chaiyanghe decoction extract according to the method in Example 1, add the prescribed amount of auxiliary materials to make granules according to the conventional method, dissolve the volatile oil with an appropriate amount of ethanol, spray evenly on the granules, dry at low temperature, and pack. 10g per bag.
[0058] (2) Preparation of Yanghe Decoction Effervescent Tablets
[0059] Prescription: Yanghe Decoction Extract 17.7
[0060] Starch 5g...
Embodiment 3
[0096] Example 3: Preparation method of Yanghe Decoction oral liquid preparation
[0097] (1) Preparation of oral liquid
[0098] Prescription: Yanghe Decoction Extract 5-80%
[0099] Sucrose 5.0-50%
[0100] Sodium cyclamate 5.0-40%
[0101] Methyl sorbate 0.001-2%
[0102] Span 20 5.0-40%
[0103] Distilled water 10-90%.
[0104] Preferred Prescription:
[0105] Yanghe Decoction Extract 17.7g
[0106] Sucrose 5.0g
[0107] Sodium cyclamate 1.5g
[0108] Span 20 2.5g
[0109] Methyl sorbate 0.02g
[0110] Make up to 60ml with distilled water.
[0111] Preparation method: prepare the Yanghe decoction extract according to the method in Example 1, add the excipients of the prescription and distilled water, then ultrafilter through an ultrafilter, fill the ultrafiltrate, and sterilize to obtain the product.
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