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Intestine toxicity syndrome vaccine oral liquid synergistic agent for livestock, poultry and aquatic product, and preparation method thereof

A technology for enterotoxic syndrome and aquatic animals, applied in the direction of medical raw materials derived from reptiles, antiviral agents, drug combinations, etc., can solve problems such as reduced electrolyte absorption, intestinal absorption disorders, and limited preventive effects, and achieve absorption rate High, wide distribution, convenient administration effect

Inactive Publication Date: 2010-12-15
海南正强超越生化技术开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

4. A large amount of electrolytes are lost: Coccidia and bacteria grow and multiply rapidly, leading to indigestion, intestinal absorption disorders, and reduced electrolyte absorption
Regarding immune additives, there is no very effective immune prevention and control measures at present. Sufficient amounts of vitamins and sodium selenite VE are commonly used, but their preventive effects are very limited and unstable, which brings great benefits to the prevention and treatment of enterotoxic syndrome. uncertainty

Method used

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  • Intestine toxicity syndrome vaccine oral liquid synergistic agent for livestock, poultry and aquatic product, and preparation method thereof
  • Intestine toxicity syndrome vaccine oral liquid synergistic agent for livestock, poultry and aquatic product, and preparation method thereof
  • Intestine toxicity syndrome vaccine oral liquid synergistic agent for livestock, poultry and aquatic product, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1: Preparation of Oral Liquid Synergist 1 of the present invention

[0020] (1) Weigh 10 grams of Atractylodes macrocephala, 15 grams of Codonopsis, 10 grams of Artemisia annua, 10 grams of myrobalan, 20 grams of pomegranate peel, 15 grams of poplar flower, 10 grams of Alisma, 2 grams of snake gall, 10 grams of ox gall, 40 grams of aloe, Rock sugar 25 grams.

[0021] (2) Decoct the raw material twice, add 8 times the amount of water for the first time, decoct for 2 hours, add 6 times the amount of water for the second time, decoct for 1 hour, combine the two decoctions, filter to obtain the filtrate, and concentrate to specific gravity 1.35 extract, add 85-95% edible glacial acetic acid for extraction, recover glacial acetic acid and concentrate, dry at 45-50°C to obtain 15.07 grams of dry extract;

[0022] (3) Grinding the dry extract into powder, adding 18 grams of neomycin, 10 grams of oxytetracycline hydrochloride and 8 grams of sulfamethoxazole sodium, ...

Embodiment 2

[0024] Embodiment two: preparation of oral liquid synergist 2 of the present invention

[0025] (1) Weigh 20 grams of Atractylodes macrocephala, 25 grams of Codonopsis pilosula, 20 grams of Artemisia annua, 25 grams of myrobalan, 25 grams of pomegranate peel, 20 grams of poplar flower, 20 grams of Alisma, 5 grams of snake gall, 20 grams of ox gall, 60 grams of aloe, Rock sugar 40 grams.

[0026] (2) Decoct the raw material twice, add 8 times the amount of water for the first time, decoct for 2 hours, add 6 times the amount of water for the second time, decoct for 1 hour, combine the two decoctions, filter to obtain the filtrate, and concentrate to specific gravity 1.35 extract, add 85-95% edible glacial acetic acid for extraction, recover glacial acetic acid and concentrate, dry at 45-50°C to obtain 24.37 grams of dry extract;

[0027] (3) Grinding the dry extract into powder, adding 25 grams of neomycin, 16 grams of oxytetracycline hydrochloride and 10 grams of sulfamethoxaz...

Embodiment 3

[0029] Embodiment three: preparation of oral liquid synergist 3 of the present invention

[0030] (1) Weigh 13 grams of Atractylodes macrocephala, 16 grams of Codonopsis pilosula, 13 grams of Artemisia annua, 13 grams of myrobalan, 21 grams of pomegranate peel, 18 grams of poplar flower, 12 grams of Alisma, 2 grams of snake gall, 12 grams of ox gall, 45 grams of aloe vera, Rock sugar 30 grams.

[0031] (2) Decoct the raw material twice, add 8 times the amount of water for the first time, decoct for 2 hours, add 6 times the amount of water for the second time, decoct for 1 hour, combine the two decoctions, filter to obtain the filtrate, and concentrate to specific gravity 1.35 extract, add 85-95% edible glacial acetic acid for extraction, recover glacial acetic acid and concentrate, dry at 45-50°C to obtain 16.75 grams of dry extract;

[0032] (3) Grinding the dry extract into powder, adding 20 grams of neomycin, 15 grams of oxytetracycline hydrochloride and 10 grams of sulfam...

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Abstract

The invention relates to a veterinary medicine composition and a preparation method thereof. An intestinal virus syndrome vaccine oral liquid synergistic agent is mainly prepared by the following raw materials by weight portion: 10 to 20 portions of atractylis ovata, 15 to 25 portions of dangshen, 10 to 20 portions of sweet wormwood herb, 10 to 25 portions of medicine terminalia fruit, 20 to 25 portions of pomegranate bark, 15 to 20 portions of Flos Poprli, 10 to 20 portions of alisma orientale, 2 to 5 portions of snake gall, 10 to 20 portions of ox-gall, 40 to 60 portions of Chinese aloe, 25to 40 portions of crystal sugar, 18 to 25 portions of neomycin, 10 to 16 portions of oxytetracycline hydrochloride and 8 to 10 portions of sulfamethoxazole sodium. The oral liquid synergistic agent can eliminate toxin in blood and toxin invaded from the outside of organisms, has the characteristic of clearing away heat and toxic materials, can kill fungus, mold and bacteria, inhibit and eliminategrowth and propagation of pathogens, and treat the intestinal virus syndrome. Moreover, the oral liquid synergistic agent has the advantages of convenience in drinking and administration, high absorptivity, wide distribution, no medicine residue, no toxic side effect, and wide safe range.

Description

【Technical field】 [0001] The invention relates to a veterinary pharmaceutical composition and a preparation method thereof. 【Background technique】 [0002] In recent years, in areas where chickens are developed in my country, there is a common phenomenon in chicken flocks, such as diarrhea, feces containing undigested feed or persimmon red feces; decreased feed intake, slow growth or weight loss, pigmentation disorders, soft Feet, dehydration, decreased feed remuneration; at the same time, autopsy for diseases characterized by tomato-like contents in the intestinal tract. At present, the prevalence of this disease is on the rise. Although the mortality rate is not high, the hidden economic loss caused is huge, and it is mistaken by farmers for "dyspepsia" or misdiagnosed as coccidia. According to the investigation and research of relevant scholars, this disease is a syndrome caused by multiple etiologies, which is called "enterotoxic syndrome". [0003] The main causes of e...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61K9/10A61P31/14A61P31/04A61P1/12A61P33/00A61P37/04A61K35/58A61K35/413A61K31/7048A61K31/65A61K31/635A61K35/583
Inventor 谢兴荣刘治西唐兆新郭世宁汪连涛王芝武帮勇吴国辉陈胜叶亚多潘永发林仕
Owner 海南正强超越生化技术开发有限公司
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