15 results about "Alisma orientale" patented technology

The application discloses a compound with the function of purgation and water excretion, which has a chemical structural formula as shown in formula (I). The compound is a new natural product of tetracyclic triterpenes, has good fat solubility and chemical stability, can be conveniently extracted from the rhizome of the herbal medicine Alisma orientale and prepared into an oral or injection dosage form. The application further provides a preparation method and application of the compound. The compound can obviously inhibit the increase of the abdominal volume and the weight of ascites of mice in a dose-dependent manner, and is a new water excretion drug with great potential.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition with hangover-alleviating and liver-protecting effects and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines: semen hoveniae, flos puerariae, rhizoma gastrodiae, pericarpium citri reticulatae, poria cocos, rhizoma alismatis, herba artemisiae scopariae, gynostemma pentaphylla, roasted rhizoma atractylodis macrocephalae, cortex magnoliae officinalis, radix paeoniae alba and honey-fried licorice root. The traditional Chinese medicine composition disclosed by the invention has the effects of relieving alcoholism, resolving damp turbidity, clearing liver and gallbladder and strengthening spleen soil. The traditional Chinese medicine composition disclosed by the invention is particularly suitable for patients suffering from alcohol fever, alcoholic liver, hyperlipidemia and liver and gall diseases mainly caused by damp turbidity and alcohol toxicity. Experimental results show that the traditional Chinese medicine composition has a good treatment effect on acute alcoholic liver injury and chronic alcoholic fatty liver, so that the traditional Chinese medicine composition has a relatively good development and utilization prospect.

The invention provides rhizoma alismatis purified polysaccharide as well as a preparation method, an identification method and application thereof, the rhizoma alismatis purified polysaccharide is a functional component with a novel structure in a traditional Chinese medicine rhizoma alismatis water extract obtained by further extraction and purification, the administration efficiency is effectively improved, and the pharmacodynamic substances are clarified; in-vivo and in-vitro experiments show that the polysaccharide can improve the antioxidant capacity of the liver and relieve inflammatory response; synthesis and metabolism of liver bile acid can be adjusted, cholestasis of the liver is relieved, and bile acid circulation is promoted so as to relieve acute liver injury caused by acetaminophen; the effect of promoting the recovery of liver injury patients is obvious; and the compound also can be used as prebiotics to improve the homeostasis of intestinal microorganisms and promote the synthesis of short-chain fatty acids so as to have beneficial effects on the liver.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine preparation for treating pleural effusion and peritoneal effusion and a preparation method thereof.The traditional Chinese medicine preparation is prepared from, by weight, 10-50 parts of traditional Chinese medicine extract, 30-70 parts of filler, 5-20 parts of enteric coating material, 5-15 parts of HPMC, 0.5-2 parts of triethyl citrate and 0.25-1.5 parts of magnesium stearate; poria cocos, polyporus umbellatus, rhizoma alismatis, astragalus membranaceus, curcuma zedoary, cassia twig, oldenlandia diffusa, sculellaria barbata, semen coicis and traditional Chinese medicine extracts are used as cores, the stability of volatile drugs is improved through an inclusion technology, and the volatile drugs are entrapped in a pH intelligent response type enteric coating material composed of aromatic ring-containing vinyl monomers, ethyl acrylate, DMAEMA and MAA. The traditional Chinese medicine preparation has the synergistic effect of efficiently inducing diuresis, activating blood circulation and eliminating tumors and enteric-coated long-acting directional delivery, and is suitable for patients with pleural effusion and peritoneal effusion, especially malignant effusion.

The invention provides a storage and fresh-keeping method of oriental waterplantain rhizome flower bolts, which comprises the following steps: preparing an inactivated bacteria solution from pantoea agglomerans and Vilnelande solid-base bacteria, and adding amino ethyoxyl vinyl glycine into a bacteria solution culture medium to construct a synergistic fresh-keeping system, in the method, a mixed bacterial agent forms a biological protection layer on the surface of the flower bolts, so that the fresh-keeping effect of the flower bolts is improved, and the storage and fresh-keeping effects of the flower bolts are improved. Meanwhile, the bacterial liquid serves as an amino ethyoxyl vinyl glycine carrier, slow release and efficient permeation of active ingredients are achieved, and ethylene synthesis is inhibited from the interior; the technology has the dual advantages of biological control and physiological regulation, is green and free of chemical residues, can remarkably maintain the integrity of cell membranes, effectively keeps the color, texture and nutrition of products, prolongs the storage period, and opens up a new way for fresh keeping of green agricultural products.

The present invention relates to a botanical composition for the treatment of vertigo and / or dizziness, comprising the rhizome of Alisma orientale; the root of Atractylodes macrocephala; the pericarp of Citri reticulatae; the pericarp of Citri reticulatae viride; and the leaves of Folium nelumbinis. The dizziness and / or dizziness in question is understood to mean dizziness and / or dizziness caused by gastric moisture or dampness. The present invention also relates to treating dizziness and / or dizziness by administering the botanical composition to a patient in need of such treatment.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition with kidney tonifying and bowel relaxing functions and a preparation method, a preparation and application thereof. The traditional Chinese medicine composition comprises the following components: wine-processed cistanche, angelica sinensis, cooked rhubarb, semen cassiae, achyranthes bidentata, radix paeoniae alba, pericarpium citri reticulatae, rhizoma alismatis, fructus aurantii and rhizoma cimicifugae. The traditional Chinese medicine composition provided by the invention is mainly used for warming the kidney, boosting essence and relaxing bowel. The traditional Chinese medicine is used for treating dry stool, constipation due to intestinal dryness, clear and long urine, soreness and weakness of waist and knees, general weakness, stomachache, abdominal distension, blood deficiency and sallow yellowness, insomnia, headache and dizziness, spontaneous perspiration and inappetence caused by kidney deficiency and body fluid deficiency; the traditional Chinese medicine is used for treating irritable bowel syndrome and menstrual disorder.

This invention relates to a method for extracting compound Alisma alkaloid A from Alisma plantago-aquatica and its application, effectively solving the problem of extracting Alisma alkaloids from Alisma plantago-aquatica and enabling its application in the preparation of drugs for treating lung cancer. This compound, Alisma alkaloid A, significantly reduces cell viability and Bcl2 expression, induces apoptosis and mitochondrial membrane depolarization in A549 lung cancer cells, and significantly increases the expression of Bax, Caspase3, and Caspase9, without affecting normal human lung epithelial cells BEAS-2B. It has the effect of inducing apoptosis in A549 cells through the mitochondrial apoptosis pathway, thus realizing the application of Alisma alkaloid A in the preparation of drugs for treating lung cancer. The method of this invention is scientifically sound, novel, unique, and easy to operate, effectively extracting compound Alisma alkaloid A from Alisma plantago-aquatica. This compound has the effect of inducing apoptosis in A549 cells through the mitochondrial apoptosis pathway, realizing the application of Alisma alkaloid A in the preparation of drugs for treating lung cancer, and expanding the medicinal and commercial value of Alisma plantago-aquatica.

A herbal medicine composition is provided for treating vertigo and / or dizziness comprising: Alisma orientale rhizome; Atractylodes macrocephala root; Citri reticulatae pericarpium; Citri reticulatae viride pericarpium; and Folium nelumbinis. The vertigo and / or dizziness of present interest should be understood to mean vertigo and / or dizziness arising as a result of water or dampness of the stomach. Methods of treating such vertigo and / or dizziness by administering the herbal medicine composition to a patient in need thereof are also provided.

The present application relates to the field of traditional Chinese medicine preparation, and particularly discloses a traditional Chinese medicine composition for invigorating the spleen, tonifying the kidney, promoting blood circulation and eliminating phlegm and lipid, and a preparation method thereof. The traditional Chinese medicine composition is prepared from fourteen kinds of raw medicinal materials, including raw red yeast rice, gynostemma pentaphyllum, cleaned hawthorn, astragalus, salvia miltiorrhiza, corn silk, prunella vulgaris, prepared rhizoma polygonati, alisma orientale, radix coicis, prepared radix falcaliae, giant knotweed, semen cassiae and licorice root. The present application can further comprise poria cocos and dried tangerine or orange peel. The present application is aimed at the pathogenesis of spleen deficiency as the root, phlegm-dampness as the branch and phlegm and blood stasis as the combination. The combination principle of invigorating the spleen, eliminating dampness, resolving phlegm, regulating qi and promoting blood circulation is adopted, and the prescription is rigorous. In the preparation method, the present application adopts the combined enzymatic hydrolysis and ultrasonic extraction technology, and combines the low-temperature drying and ultrafine grinding process, so that the extraction efficiency of effective components is significantly improved. The present application also provides various dosage forms, such as decoction, granules, tablets, capsules, pills, powders, oral liquid and ointment, which have good lipid-lowering, phlegm-eliminating and blood-activating effects and safety.

The invention discloses an anti-tumor and anti-AIDS pharmaceutical composition and a preparation method thereof. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 220 to 260 grams of herba hyperici japonici, 230 to 250 grams of philippine flemingia root, 235 to 245 grams of rhizoma dioscoreae septemlobae, 230 to 250 grams of beefwood-like clubmoss herb, 150 to 170 grams of obscured homalomena rhizome, 90 to 110 grams of zaocys dhumnades, 155 to 165 grams of scandent schefflera stem and leaf, 220 to 260 grams of schisandra propinqua, 230 to 250 grams of lycopodium clavatum, 220 to 260 grams of common leafflower herb, 90 to 110 grams of gastrodia elata and 35 to 45 grams of white spirit. The preparation method of the pharmaceutical composition comprises the following steps: respectively taking the raw materials in parts by weight, cleaning the herba hyperici japonici, the philippine flemingia root, the rhizoma dioscoreae septemlobae, the beefwood-like clubmoss herb, the obscured homalomena rhizome, the garter snake, the scandent schefflera stem and leaf, the schisandra propinqua, the lycopodium clavatum, the common leafflower herb and the gastrodia elata, feeding into a crusher for crushing, sieving with a 60-80-mesh sieve after crushing, uniformly putting the sieved Chinese herbal medicine granules into an extraction tank, and extracting for 2-3 hours to obtain the pharmaceutical composition. And adding white spirit, sealing and soaking for 15 days, and filtering to remove residues to obtain a finished product.

The application relates to a triterpenoid compound A2 extracted from oriental alisma, and a preparation method thereof. The preparation method is as follows: oriental alisma is dried and crushed, soaked with acetone at room temperature, broken and extracted, filtered, and the filter liquor is combined and concentrated under reduced pressure to obtain an extract; the extract is extracted with equal amounts of petroleum ether, dichloromethane, ethyl acetate and n-butanol in sequence, concentrated and dried to obtain a petroleum ether part, a dichloromethane part, an ethyl acetate part, an n-butanol part and a water part; the dichloromethane part is dissolved in methanol, mixed with silica gel, loaded on a column and eluted four times to obtain a target flow fraction; the target flow fraction is loaded on a chromatographic column, the flow fraction in the retention time is collected, concentrated and dried, and the triterpenoid compound A2 is obtained. The raw material is rich, the unique preparation method is adopted, the compound A2 can improve airway inflammation and airway hyperresponsiveness of OVA-induced allergic asthma, can be used for preparing a medicine for treating allergic asthma, expands the medicinal value and economic value of the oriental alisma, and has great economic and social benefits.

The application relates to the field of traditional Chinese medicine compositions, and particularly discloses a traditional Chinese medicine composition for treating chronic prostatitis and a preparation method thereof; the traditional Chinese medicine composition comprises the following steps: S1: preparing a matrix material by taking amphoteric starch, L-arginine hydrochloride, hydroxypropyl cellulose, water and glutaraldehyde; S2: preparing traditional Chinese medicine extracts by taking sophora flavescens, psoralea corylifolia, patrinia, cuscuta chinensis, herba epimedii, red peony root, verbena, Chinese chive seed, Chinese yam, prepared rehmannia, cornus officinalis, radix paeoniae rubra, alisma orientale, poria cocos, cassia, prepared aconite, and yam of china; S3: preparing a traditional Chinese medicine gel by taking the traditional Chinese medicine extracts, water and the matrix material; S4: preparing a warming agent by taking an emulsifier, water, n-docosane and hydroxypropyl cellulose; and S5: uniformly mixing the traditional Chinese medicine gel, borneol, the warming agent, poloxamer, carboxymethyl cellulose, hydroxypropyl-BETA-cyclodextrin and ethanol, controlling the pH value to be 7.3-7.5, and obtaining the traditional Chinese medicine composition.

The application discloses a traditional Chinese medicine composition for treating knee synovitis and a preparation method thereof, and particularly relates to the field of traditional Chinese medicines. The composition comprises a blood-activating and swelling-eliminating plaster and a qi-tonifying and swelling-eliminating soup. The blood-activating and swelling-eliminating plaster comprises angelica sinensis, ligusticum chuanxiong, red peony root, persicae semen, safflower, phellodendri cortex, raw olibanum, raw myrrh, dragon's blood, radix angelicae pubescentis, taraxacum, radix sanguisorbae, curcuma, raw rhubarb and mirabilite; and the qi-tonifying and swelling-eliminating soup comprises smilax glabra, atractylodes, coix seed, phellodendri cortex, radix cyathulae, motherwort, raw astragalus, alisma orientale, anemarrhena asphodeloides, psoralea, persicae semen, safflower and licorice. The research result of the blood-activating and swelling-eliminating plaster and the qi-tonifying and swelling-eliminating soup used in combination for treating knee synovitis has not only help to understand the action mechanism of the external treatment technology of traditional Chinese medicine, but also helps to develop a new treatment method with definite curative effect and no toxic side effect, and has remarkable social and economic benefits.

The application belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition and medical application thereof. The traditional Chinese medicine composition is mainly prepared from ginseng stem and leaf saponin, Schisandra chinensis, Astragalus membranaceus, Chinese yam, Rehmannia glutinosa, raspberry, Ophiopogon japonicus, Poria cocos, Bupleurum smithii, Alisma orientale and Medicago polymorpha L. The ginseng and astragalus blood sugar lowering preparation prepared from the traditional Chinese medicine composition has obvious blood pressure lowering effect, and can be used for treating hypertension, especially salt-sensitive hypertension.