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Medicament for preventing and controlling white diarrhea disease

A pullorum and drug technology, applied in the fields of medicine and medical engineering, can solve the problems of poor curative effect, reduced egg production rate of adult chickens, and difficult recovery.

Inactive Publication Date: 2009-01-14
HEBEI AGRICULTURAL UNIV.
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But with the passage of time, its disadvantages have become increasingly prominent in clinical practice. For example, sulfa drugs can inhibit the growth and development of chicks, and the egg production rate of adult chickens is greatly reduced, and it is difficult to recover, and it interferes with the intake of feed and drinking water by chickens; For furan drugs, furazolidone (also known as "furazolidone") is better, but the concentration of the drug should not be excessive (≤0.066%), the drinking water should be fully dissolved, and the ingredients should be uniform, otherwise it will easily cause chicken poisoning and death. In this regard, the author I have a deep experience. In more than 20 years of clinical practice, it is not uncommon for chicks to die of furazolidone poisoning, or even the whole flock is wiped out. The lesson is painful; antibiotics such as chloramphenicol and oxytetracycline are more effective
However, with decades of long-term use, even indiscriminate use and abuse, the curative effect of western medicine is getting worse and worse, and the drug resistance is getting stronger and stronger. Drug residues pose a threat to meat and egg food safety and become a major public hazard. Therefore, my country's agricultural The Ministry of Foreign Affairs has promulgated relevant laws and regulations to ban some western medicines such as chloramphenicol and furazolidone in edible animals; while other commercially available Chinese veterinary medicines such as Bailijing and Bailian do not have the disadvantages of the above-mentioned western medicines, but there are also problems in formula composition and application methods. Some technical defects, either the curative effect is not good because the formula is not rigorous, or the drug powder is often directly mixed and fed in the application method, which delays the absorption rate of the active ingredients of the drug by sick birds, and its curative effect is not satisfactory

Method used

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  • Medicament for preventing and controlling white diarrhea disease
  • Medicament for preventing and controlling white diarrhea disease
  • Medicament for preventing and controlling white diarrhea disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Test time: April 2000.

[0014] Place for the test: Xia Yuzhen Chicken Farm, Guantao County, Hebei Province.

[0015] Test chicken flock: 11 days old, 3000 Xingza 579 commercial generation layer hens, because the temperature of the brooding room was cold and sometimes hot, outbreaks of pullorum disease occurred in the chicks, and the same group lived in the same house.

[0016] Drug for testing: namely the pure Chinese medicine preparation of the present invention, each raw material drug is purchased from Dongfang Pharmaceutical City, Anguo City, Hebei Province, and its composition is expressed in parts by mass: 5 parts of Pulsatilla pulsatillae, 5 parts of Dan cortex, 5 parts of Qin cortex, 5 parts of purslane, 5 parts of myrobalan, 3 parts of gentian, 3 parts of Phellodendron, 3 parts of realgar, 3 parts of Huoxiang, 2 parts of garlic, 2 parts of woody fragrance, 2 parts of rhubarb, 2 parts of talc, and 2 parts of licorice. The above-mentioned Chinese herbal medicine...

Embodiment 2

[0030] Test time: November 2002.

[0031] The test site: Li Limin Chicken Farm, Neiqiu County, Hebei Province.

[0032] Test chicken flock: 17 days old, 2200 Hailan brown commercial layer hens, due to the low temperature in the brooding room, the chicken flock suffered from cold and broke out the pullorum disease of the chicks, and the same flock lived in the same house.

[0033] Drug for testing: namely the present invention, the procurement of raw materials is the same as in Example 1, and its composition is expressed in parts by mass: 10 parts of Pulsatilla pulsatillae, 10 parts of Dan Cortex, 10 parts of Qin Pi, 10 parts of purslane, 10 parts of Myrobalan, Gentiana 6 parts of grass, 6 parts of cortex, 6 parts of realgar, 6 parts of Huoxiang, 4 parts of garlic, 4 parts of woody fragrance, 4 parts of rhubarb, 4 parts of talc, and 4 parts of licorice. Processing method is with embodiment 1.

[0034] Test group: 1100 rats, treated with the medicine of the present invention. ...

Embodiment 3

[0047] Test time: August 2003.

[0048] The test location: Yang Guozhang Chicken Farm in Yanshan County, Hebei Province.

[0049] Test chickens: 15 days old, 4,000 Dajiang AA broiler chickens, because of poor sanitation in the brooding room, an outbreak of pullorum in the chicks, the same group and the same house.

[0050] Drug for testing: namely the present invention, the raw material procurement is the same as in Example 1, and its composition is expressed in parts by mass: 20 parts of Pulsatilla pulsatillae, 20 parts of Cortex paeonol, 20 parts of Cortex chinensis, 20 parts of purslane, 20 parts of Myrobalan, Gentiana 12 parts of grass, 12 parts of cork, 12 parts of realgar, 12 parts of Huoxiang, 6 parts of garlic, 6 parts of woody fragrance, 6 parts of rhubarb, 6 parts of talc, and 6 parts of licorice. Processing method is with embodiment 1.

[0051] Test group: 2000 rats, treated with the medicine of the present invention.

[0052] Control group: 2000 rats, treated wi...

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Abstract

The present invention discloses a medicine which is used for preventing and treating pullorum. The medicine comprises the ingredients of the following weight portions: 5 to 20 portions of Chinese pulsatilla, 5 to 20 portions of cortex moutan, 5 to 20 portions of bark of Chinese ash, 5 to 20 portions of purslane, 5 to 20 portions of myrobalan, 3 to 12 portions of radix geutianae, 3 to 12 portions of corktree, 3 to 12 portions of realgar, 3 to 12 portions of ageratum, 2 to 6 portions of garlic, 2 to 6 portions of banksian rose, 2 to 6 portions of rhubarb, 2 to 6 portions of talc and 2 to 6 portions of licorice. The herbs are insolated (excepting that the fresh garlic can be used), weighed, crushed, filtered by a sieve with 60 to 80 meshes, and mixed well, so as to prepare the medicine. When in clinical use, the medicine is dipped for 30 to 60 minutes in boiling water, so that the effective ingredients can be fully dissolved and separated to facilitate the absorption in the body of the sick chicken. Simultaneously, a small amount of sugar and Vc are added to improve the medicinal effects. The medicine has high cure rate, no adverse reaction, no drug residues in the body, and nearly no drug resistance. The production of the medicine has the advantages of easily acquirable raw materials, simple preparation, convenient use, and capability of wide promotion and application in the chicken breeding industry.

Description

Technical field: [0001] The invention belongs to the technical field of medicine and medical engineering, in particular to a medicine for preventing and treating pullorum. Background technique: [0002] my country is already a big chicken raising country in the world, and the chicken industry is still developing. However, chicken disease is still a major factor that endangers the health of chicken flocks and affects the sustainable and steady development of the chicken industry. Such as poultry salmonellosis (including pullorum, poultry typhoid and poultry paratyphoid three diseases with different antigen structures, but the same prevention and treatment drugs), this disease occurs all over the world, posing a serious threat to the development of poultry industry, this disease There are as many as 25,000 isolates of this disease, and many types of this disease can cause human infection and food poisoning, which should not be underestimated. Chickens of various breeds are s...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P31/04A61K33/12A61K33/36
Inventor 鹿瑞麟崔继良邳明伟郑洁袁秀丽郭欣乔铁库李秀文
Owner HEBEI AGRICULTURAL UNIV.
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