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Animal compound sodium closantel injection

A technology of compound cylindronate sodium and cycihalide sodium is applied in the directions of pharmaceutical formulations, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc. It is not good, easy to cause poisoning and other problems, and achieves the effect of reducing the frequency of medication, expanding the scope of anti-insect, and wide clinical application.

Inactive Publication Date: 2009-05-06
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In this way, it is cumbersome to use separate medicines to drive and kill parasites in vivo and in vitro, and for anti-parasite drugs, organophosphorus or other insecticides are generally used. If the dose is not well controlled, it may easily cause poisoning, or animals may lick their bodies and cause poisoning.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] 1. Put 70kg of iodoclosamide sodium into 150L of propylene glycol, heat to 50-60°C and stir for 10-25min until clear;

[0017] 2. Take 200L of glycerin formal, add 5kg of ivermectin and stir to dissolve;

[0018] 3. Combine the solutions prepared in step 1 and step 2, add glycerin formal to 1000L, stir evenly, keep for 15-20min, and make it after the liquid medicine is clarified.

Embodiment 2

[0020] 1. Put 65kg of iodoclosamide sodium into 130L of propylene glycol, heat to 50-60°C and stir for 10-25min until clear;

[0021] 2. Take 200L of glycerin formal, add 6kg of ivermectin and stir to dissolve;

[0022] 3. Combine the solutions prepared in step 1 and step 2, add glycerin formal to 1000L, stir evenly, keep for 15-20min, and make it after the liquid medicine is clarified.

Embodiment 3

[0024] 1. Put 60kg of iodoclosamide sodium into 100L of propylene glycol, heat to 50-60°C and stir for 10-25min until clear;

[0025] 2. Take 200L of glycerin formal, add 7kg of ivermectin and stir to dissolve;

[0026] 3. Combine the solutions prepared in step 1 and step 2, add glycerin formal to 1000L, stir evenly, keep for 15-20min, and make it after the liquid medicine is clarified.

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PUM

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Abstract

The invention discloses a veterinary compound sodium closantel injection which reduces poisoning probability generated when killing the parasites of cows and sheep. The invention belongs to a medical product which contains organic effective components. The preparation method thereof is as follows: 30 to 100kg of sodium closantel is added into 50 to 200L of propanediol, heated to the temperature of 50 to 60 DEG C and stirred for 10 to 25min until the mixture is clear; 1 to 20kg of ivermectin is added into 200L of glycerol formal and stirred for 15 to 20min until the liquid is clear; after the two obtained liquids are combined, the glycerol formal is added to 1000L, stirred uniformly and maintained for 15 to 20min; and after the medicine liquid is clear, the veterinary compound sodium closantel injection is obtained. The invention adopts a compound preparation, is highly effective to the parasites of cows and sheep, can be broadly applied to the parasites of cows and sheep, reduce the infection rate of the parasites and increase the weights of cows and sheep.

Description

technical field [0001] The invention relates to a medical product containing organic active ingredients, such as an antiparasitic drug, in particular to a veterinary compound closantamide sodium injection. Background technique [0002] Cattle and sheep parasitic infection is a highly susceptible disease for cattle and sheep, which can cause poor growth, increased feed consumption, and decreased resistance of cattle and sheep. [0003] Cattle and sheep parasites are composed of internal parasites such as trematodes, roundworms, hookworms, tapeworms and some external parasites such as lice, skin maggots, mites, etc. Traditional parasite repellent drugs such as clocyanamide sodium injection Liquid and ivermectin injection have certain limitations in repelling and killing parasites. [0004] For example, Closantel Sodium (Closantel Sodium) is an anthelmintic drug, which is effective against cattle and sheep liver flukes, gastrointestinal nematodes and sheep tyrosophila, but is ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61K47/10A61P33/14A61K31/277
Inventor 徐克福
Owner TIANJIN SHENGJI GRP CO LTD
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