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Oral Chinese medicinal composition as well as preparing, taking and quality inspecting methods and use thereof

A quality inspection and composition technology, applied in the direction of drug combination, pharmaceutical formula, antipyretics, etc., can solve the problems of large dosage, difficult industrial production, and many medicinal tastes

Active Publication Date: 2009-05-20
SICHUAN SUNNYHOPE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this invention uses a lot of medicinal flavors and has not been extracted and refined, so the dosage is relatively large; what is more troublesome is that during the preparation process, mung beans must be put into fresh animal gall and placed in the shade until the bile is absorbed by mung beans It can only be used later, so it is difficult to implement in industrial production

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] preparation:

[0081] Take money grass 280g, rhubarb 60g, capillary wormwood 200g, Achyranthes bidentata 160g, Poria cocos 220g, Alisma 140g, Qingpi 120g, Bupleurum 160g, Toosendan 160g, Muxiang 120g, Cyperus cyperi 100g, Magnolia officinalis 100g, oyster (calcined ) 180g, soak in water for 2 hours, decoct three times, add 10 times the amount of water each time, decoct for 1.5 hours, combine the decoction, add 80g of ox bile, filter, concentrate the filtrate to a relative density of 1.12-1.15 (60°C), and refrigerate After 48 hours, filter, concentrate the filtrate to about 1000ml, add 2g of sodium benzoate, add water to adjust the total amount to 1000ml, shake well, let stand, filter, fill, and sterilize to obtain. Orally, 50ml each time, 3 times a day.

[0082] Quality inspection of finished products:

[0083] 1. Identification: (1) Take 30ml of this product, shake and extract 3 times (30, 20, 20ml) with diethyl ether, combine the diethyl ether extract (water liquid ...

Embodiment 2

[0103] preparation:

[0104] Take 300g desmodium, 60g rhubarb, 180g capillary, 150g Achyranthes bidentata, 240g poria cocos, 120g Alisma, 120g green bark, 150g bupleurum, 150g toosendan, 120g woody incense, 120g Cyperus cyperi, 90g magnolia officinalis, oyster (calcined ) 200g, 5g of dried sheep gallbladder paste, soak in water for 2 hours, decoct twice, add 8 times the amount of water each time, decoct for 1 hour, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.20-1.25 (60°C) , add three times the amount of ethanol, refrigerate for 48 hours, filter the supernatant, recover the ethanol from the filtrate, concentrate, dry, pulverize, add an appropriate amount of starch to granulate, dry, sieve, pack into capsules, and make 400 capsules. Take orally, 20 capsules at a time, 2 times a day.

[0105] Quality inspection of finished products:

[0106] 1. Identification: (1) Take about 5g of the contents of this product, shake with water, extrac...

Embodiment 3

[0125] preparation:

[0126] Take 400kg of Desmodium, 40kg of Rhubarb, 170kg of capillary, 140kg of Achyranthes bidentata, 210kg of Poria, 80kg of Alisma, 120kg of Toosendan, and 140kg of oyster. Decoction, stand overnight, filter the supernatant, concentrate the filtrate to a relative density of 1.20-1.25 (60°C), filter, precipitate with alcohol twice, filter the supernatant, recover ethanol from the filtrate, concentrate, dry, pulverize, add Appropriate amount of starch is granulated, dried, granulated, added with appropriate amount of magnesium stearate, compressed into tablets, and made into 200,000 tablets. Take orally, 10 tablets at a time, 3 times a day.

[0127] Take 2400g of goat bile, heat and concentrate it to a thick paste with a relative density of 1.25-1.30 (80°C), dry it at 70-85°C until the water content is less than 5%, make a dry paste, grind it into fine powder, add appropriate amount of starch, Mix well, put into capsules, make 1000 capsules, and get read...

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Abstract

The invention discloses an orally-administered traditional Chinese medicine composition. The composition is prepared from traditional Chinese medicine raw materials such as desmodium, rhubarb, Herba Artemisiae Capillaris, achyranthes, Alisma orientale, tuckahoe, an animal gall product and so on, has functions of clearing heat and promoting diuresis, soothing liver and benefiting gall, regulating qi and dredging stranguria, promoting urination, promoting the secretion of bile, resisting inflammation, killing pain, relieving fever, resisting bacteria and so on, is used for treating diseases such as cholelithiasis and urinary calculus or hepatobiliary lithiasis caused by damp-heat of liver and gallbladder as well as symptoms such as right epigastric pain, upper abdomen fullness and distention, nausea, anorexia to greasiness, jaundice, yellow and greasy fur or osphyalgia, hematuria and so on, and has definite treatment effect and no apparent adverse reaction. The invention also relates to a preparation method, an administration method and a quality checking method for the orally-administered traditional Chinese medicine composition.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a traditional Chinese medicine oral medicine prepared from traditional Chinese medicines as main raw materials. The invention also relates to the preparation method, administration method, quality inspection method and application of the oral Chinese medicine composition. Background technique [0002] Cholelithiasis or urolithiasis is a common clinical disease. Cholelithiasis refers to stone lesions of the gallbladder, common bile duct, and intrahepatic bile duct, including residual stones after biliary surgery, often manifested as right upper quadrant pain, upper abdominal fullness, nausea, anorexia, greasy, jaundice, or yellow greasy tongue coating. Cholelithiasis belongs to the category of hypochondriac pain in traditional Chinese medicine. The syndrome is mainly based on qi stagnation and damp heat. The treatment should soothe the liver and promote qi, clear away heat and damp...

Claims

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Application Information

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IPC IPC(8): A61K36/884A61K36/8905G01N21/25G01N21/31G01N21/33G01N30/90A61P1/16A61P7/10A61P29/00A61P31/00A61K35/413A61K35/56A61K35/618
Inventor 郭成辉吴聪梁灏
Owner SICHUAN SUNNYHOPE PHARM CO LTD
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