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A magnetic sensor device for and a method of sensing magnetic particles

A magnetic sensor and magnetic particle technology, applied in the measurement of magnetic particles, the size/direction of magnetic fields, the measurement of magnetic bead-labeled molecules, etc.

Inactive Publication Date: 2009-05-20
KONINKLIJKE PHILIPS ELECTRONICS NV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0010] However, under adverse conditions, crosstalk can still be an issue

Method used

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  • A magnetic sensor device for and a method of sensing magnetic particles
  • A magnetic sensor device for and a method of sensing magnetic particles
  • A magnetic sensor device for and a method of sensing magnetic particles

Examples

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Embodiment Construction

[0051] The description of the figures is schematic. In different figures, similar or identical elements have the same reference signs.

[0052] In a first embodiment, the device according to the invention is a biosensor, and with reference to figure 1 with figure 2 to describe the biosensor. Biosensors detect magnetic particles in samples such as fluids, liquids, gases, viscoelastic media, gels or tissue samples. Magnetic particles can be of small size. Nanoparticles mean particles with at least one dimension between 0.1 nm and 1000 nm, preferably between 3 nm and 500 nm, more preferably between 10 nm and 300 nm. Magnetic particles can acquire a magnetic moment due to an applied magnetic field (eg, they can be paramagnetic). The magnetic particles may be composites, eg, a magnetic particle comprising one or more small magnetic particles within or attached to a non-magnetic material. Particles can be used as long as they produce a non-zero response to a modulated magnet...

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Abstract

A magnetic sensor device (300) for sensing magnetic particles (15), the magnetic sensor device (300) comprising a magnetic field generator unit (12) adapted for generating a magnetic field, an excitation signal source (302) adapted for supplying the magnetic field generator unit (12) with a static electric excitation signal, an excitation switch unit (303) adapted for switching between different modes of electrically coupling the excitation signal source (302) to the magnetic field generator unit (12), and a sensing unit (11) adapted for sensing a signal indicative of the presence of the magnetic particles (15) in the generated magnetic field.

Description

technical field [0001] The present invention relates to a magnetic sensor device for sensing magnetic particles. [0002] The invention further relates to a method of sensing magnetic particles. [0003] Furthermore, the invention relates to a program element. [0004] Furthermore, the present invention also relates to a computer-readable medium. Background technique [0005] A biosensor is a device for detecting an analyte that combines a biological component with a biochemical detector component or a physical detector component. [0006] Magnetic biosensors can use the giant magnetoresistance effect (GMR) to detect magnetic biomolecules or detect biomolecules labeled with magnetic beads. [0007] Hereinafter, a biosensor using the giant magnetoresistance effect will be described. [0008] WO 2005 / 010542 discloses the use of integrated magnetic sensor elements or on-chip magnetic sensor elements for detecting or determining the presence of magnetic particles. The devic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01R33/06G01R33/09G01R33/12G01R33/54G01N27/72
CPCG01R33/12G01R33/1269G01N2015/0065G01R33/1276G01R33/09
Inventor H·杜里克J·A·H·M·卡尔曼J·J·A·托尔
Owner KONINKLIJKE PHILIPS ELECTRONICS NV
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