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Antiphlogistic analgesic Capparis spinosa L. catablasm and preparation method thereof

An anti-inflammatory and pain-relieving technology, which is applied in the field of the balsam pear and its preparation, achieves the effects of less allergic reaction, obvious effect and simple preparation method.

Inactive Publication Date: 2013-01-16
石河子大学医学院第一附属医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The Chinese patent notification number is CN11234375, which discloses a method patent for extracting anti-arthritis effective parts from the vine of the plant, but the deficiency of this method is that it does not provide a kind of anti-inflammatory and analgesic effect for the vine of the plant. way of administration, and there is no such modern external dosage form as cataplasm

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Grind the vine into a coarse powder, pass through a 10-mesh sieve, add 7 times the amount of 70% ethanol to extract and reflux twice, each time for 3 hours, filter through a 150-mesh sieve, combine the filtrates from the two times, recover the ethanol, and concentrate to It is equivalent to 1g of the liquid extract of the vine, and it is dried to obtain the ethanol extraction powder of the vine; the preparation method of the cataplasm of the vine: the first step: fully swell 1 part of carbomer with water to obtain A Phase, second step: add 0.1 part of ethylparaben to 10 parts of glycerin, then add 0.1 part of aluminum sulfate to get phase B, then mix phase A and phase B; The extracted powder is dispersed and dissolved in water, and then 0.1 part of citric acid is added to the aqueous solution of the ethanol extract of the mallet vine to dissolve to obtain phase C; the fourth step: add phase C to the mixture of phase A and phase B , fully stirred into a jelly-like substa...

Embodiment 2

[0015] Crush the vine into a coarse powder, pass through a 20-mesh sieve, add 6 times the amount of 80% ethanol to extract and reflux 3 times, each time for 2 hours, filter with a 100-mesh sieve, combine the filtrates for 3 times, recover the ethanol, and concentrate to The liquid extract equivalent to 1g of vine vine, dry to obtain the ethanol extraction powder of vine vine; the preparation method of cataplasm of vine vine: the first step: fully swell 2 parts of sodium carboxymethyl cellulose with water , to obtain phase A, the second step: add 0.1 part of benzoic acid to 20% glycerin, then add 0.1 part of aluminum chloride to obtain phase B, then mix phase A and phase B; The ethanol extraction powder is dispersed and dissolved in water, and then 0.1 part of citric acid is added to the aqueous solution of the ethanol extract of Hazelnut vine to dissolve to obtain phase C; the fourth step: add phase C to the mixture of phase A and phase B , fully stirred into a jelly-like subs...

Embodiment 3

[0017] Grind the vine into a coarse powder, pass through a 30-mesh sieve, add 8 times the amount of 85% ethanol to extract and reflux 4 times, each time for 1 hour, filter with a 200-mesh sieve, combine the filtrates for 4 times, recover the ethanol, and concentrate to Equivalent to 1g of the liquid extract of the vine, dry it to obtain the ethanol extraction powder of the vine; the preparation method of the cataplasm of the vine: the first step: fully swell 2 parts of sodium polyacrylate with water to obtain A phase, the second step: add 0.4 parts of ethylparaben to 30 parts of propylene glycol, then add 0.3 parts of glyoxate to obtain phase B, then mix phase A and phase B; The ethanol extraction powder is dispersed and dissolved in water, and then 0.2 parts of tartaric acid is added to the aqueous solution of the ethanol extract of Hazelnut vine to dissolve to obtain phase C; the fourth step: add phase C to the mixed solution of phase A and phase B, After fully stirring into...

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Abstract

The invention discloses an anti-inflammation-analgesia capparis spinosa cataplasm and a preparation method thereof. The invention can be taken off and stuck on at any time, improving the adaptability of a patient. The drug is a capparis extract, the stroma is prepared, according to a certain mixture ratio, by water-soluble polymer skeletal materials, cementing compound, filling agent, cross-linking agent, pH regulator, humectant, preservative, transdermal enhancer, and the like, which have different mixture ratios. The invention has the advantages that the anti-inflammation-analgesia therapeutic effectiveness is obvious, the drug-loading rate of the stroma is large, the transdermal absorption effect is good, the use is convenient, the sticking is comfortable, the irritation to skin is small, and the compliance of patients is high.

Description

technical field [0001] The present invention relates to a catarrh cataplasm with anti-inflammatory and analgesic effects and a preparation method thereof. Background technique [0002] Hammer fruit vine is the fruit of capers of the genus Caperiaceae, which is widely distributed in Xinjiang. It is a commonly used ethnic medicine and an excellent sand-fixing plant in the local area. It was first reported in "Xinjiang Chinese Herbal Medicine". In Uighur medicine, it is warm in nature and has the functions of expelling wind, dispelling cold, dehumidification, reducing swelling, and relieving pain. The affected area is used for the treatment of rheumatoid arthritis, and has a long history of Uighur folk application. In Saudi Arabia, mallet vine is also a traditional medicine for treating rheumatism and arthritis. However, due to the backwardness of the way of administration, the mallet vine causes strong irritation on the external application of patients, which limits its wid...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61K9/70A61P29/00
Inventor 王新春陈文邢建国张华韩博张永军袁勇王晋
Owner 石河子大学医学院第一附属医院
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