Compound for preventing osteoporosis and osteoarthrosis

A technology for osteoarthritis and osteoporosis, used in bone diseases, drug combinations, active ingredients of phosphorus compounds, etc., can solve the problem that calcium cannot be fully absorbed and utilized by the human body, so as to increase bone density and improve bone calcium content. Effect

Active Publication Date: 2009-09-23
哈药集团股份有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention aims to solve the problem that existing calcium supplements can only simply supplement calcium, and the supplemented calcium cannot be fully absorbed and utilized by the human body, and provides a composition for preventing osteoporosis and osteoarthrosis

Method used

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  • Compound for preventing osteoporosis and osteoarthrosis

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Effect test

specific Embodiment approach 1

[0008] Specific embodiment one: The composition for preventing osteoporosis and osteoarthropathy of the present embodiment is composed of 10-90 parts of glucosamine, 10-90 parts of calcium, and 0.1-40 parts of casein phosphopeptide in parts by weight. , 0.1-40 parts of drynaria fortunei, 0.0001-0.09 parts of vitamin K and 0.81-208 parts of auxiliary materials.

[0009] The composition of this embodiment can be made into tablets, film-coated tablets, chewable tablets, buccal tablets, effervescent tablets, dispersible tablets, capsules, soft capsules, oral liquids, suspensions, granules, and powders.

specific Embodiment approach 2

[0010] Embodiment 2: The difference between this embodiment and Embodiment 1 is that the auxiliary materials contain binders, fillers and lubricants. Others are the same as in the first embodiment.

[0011] In this embodiment, the weight ratio of the binder, the filler and the lubricant is 1:1:1.

specific Embodiment approach 3

[0012] Specific embodiment three: the difference between this embodiment and specific embodiment two is: binder is polyvinylpyrrolidone, starch slurry, hypromellose, carmellose, xanthan gum aqueous solution, syrup, sugar-containing starch Paste (a mixture of syrup and starch slurry), gelatin slurry with a mass concentration of 2% to 10%, sodium alginate aqueous solution with a mass concentration of 1% to 5%, gum arabic, methyl cellulose, liquid glucose, ethyl cellulose One or more mixtures of tragacanth gum with a mass concentration of 0.5% to 5%, carbomer, polyvinyl alcohol 4000, ethanol with a mass concentration of 10% to 95%, and water. Others are the same as in the second embodiment.

[0013] In this embodiment, when the binder is composed of two or more substances, they are mixed in any ratio.

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Abstract

The invention relates to a compound for preventing osteoporosis and osteoarthrosis. The compound relates to a compound for preventing osteonosuses. The compound for preventing osteoporosis and osteoarthrosis solves the problem that: the prior calcium replenishing agent can purely replenish calcium, while the replenished calcium cannot be fully absorbed and utilized by the human body. The compound for preventing osteoporosis and osteoarthrosis comprises the following components by weight portion: 10 to 90 portions of glucosamine, 10 to 90 portions of calcium agent, 0.1 to 40 portions of casein phosphopeptide, 0.1 to 40 portions of drynaria rhizome extract, 0.0001 to 0.09 portion of vitamin K and 0.81 to 208 portions of supplementary materials. The compound for preventing osteoporosis and osteoarthrosis can obviously improve the bone calcium content and bone density; and the replenished calcium agent can be fully absorbed and utilized.

Description

technical field [0001] The present invention relates to a composition for preventing bone disease. Background technique [0002] With the development of my country's population aging process, medication for the elderly has become the focus of medical research. Osteoporosis and osteoarthrosis, as common and frequently-occurring diseases worldwide, have brought great suffering to the elderly and brought great pressure to the society. The incidence of osteoporosis and osteoarthrosis is very high in our country , accounts for about 10% of the population, and the incidence rate is as high as 60% to 70% among the population over the age of 50. Therefore, osteoporosis and osteoarthropathy have become one of the most common multiple diseases among middle-aged and elderly people in my country. Early osteoporosis can cause complications such as bone pain and shortened limbs, while long-term illness can cause serious consequences such as fractures and osteoarthritis. At present, the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/02A61P19/02A61P19/10A61K36/11A61K33/06A61K31/122A61K31/7008A61K33/42A61K31/191A61K31/19A61K31/375A61K31/047
Inventor 金铉煜
Owner 哈药集团股份有限公司
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