Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Process for forming clear, wettable silicone hydrogel articles

A silicone, hydrophilic polymer technology used in the field of forming molded articles

Inactive Publication Date: 2009-10-28
JOHNSON & JOHNSON VISION CARE INC
View PDF34 Cites 14 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, many are not miscible with water, requiring the use of complex solvent and water exchange methods

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Process for forming clear, wettable silicone hydrogel articles
  • Process for forming clear, wettable silicone hydrogel articles
  • Process for forming clear, wettable silicone hydrogel articles

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-11

[0163]A reaction mixture was prepared consisting of 80% by weight monomer component (amounts listed in Table 1) and 20% by weight diluent (listed in Table 1). The reaction mixture was degassed at about 600-700 mmHg for about 30 minutes at ambient temperature. The reaction mixture was then placed in a thermoplastic contact lens mold (front curve made from Zeonor, back curve made from polypropylene) at 55±5°C at 1.2-1.8 mW / cm under a nitrogen atmosphere. 2 , irradiated with Philips TL20W / 03T fluorescent lamp for 25 minutes. The resulting lenses were manually demolded and released by immersing the lenses in a front curve (FC) mold in DI water at 90(±10)°C for about 2 minutes. If the lens fails to release from the FC mold within 2 minutes, the lens is kept in DI water at 90(±5)°C, using a disposable straw, sprayed with the same DI water. If the lens still does not release from the FC, manually wipe the lens from the FC. The lenses are then transferred to jars and undergo two "c...

Embodiment 12-21

[0178] A reaction mixture was prepared consisting of 55% by weight monomer component (amounts listed in Table 1) and 45% by weight diluent (mixture of 55% TPME and 45% co-diluent listed in Table 3). The reaction mixture was degassed at about 600-700 mmHg for about 30 minutes at ambient temperature. The reaction mixture was then placed in a thermoplastic contact lens mold (front curve made from Zeonor, back curve made from polypropylene) at 55±5°C at 1.2-1.8 mW / cm under a nitrogen atmosphere. 2 , irradiated with Philips TL 20W / 03T fluorescent lamp for 25 minutes. The resulting lenses were manually demolded and released by immersing the lenses in a front curve (FC) mold in DI water at 90(±10)°C for about 5 minutes. If the lens fails to release from the FC mold within 5 minutes, keep the lens in DI water at 90(±5)°C, using a disposable straw, spray with the same DI water. If the lens still does not release from the FC, manually wipe the lens from the FC. The lenses are then tr...

Embodiment 22

[0183] Lenses were prepared as in Example 13, except that the release was done in the packaging solution. That is, the resulting lenses were manually demolded and released by immersing the lenses in a front-curve (FC) mold in a packaging solution at 90 (±10)° C. for about 5 minutes. If the lens fails to release from the FC mold within 5 minutes, keep the lens in the packaging solution at 90(±5)°C, and spray it with the same packaging solution using a disposable pipette. If the lens still does not release from the FC, manually wipe the lens from the FC. The lenses are then transferred to the jar and go through two "change-out" steps - step 1) holding the packaging solution at 25(±5)°C for a minimum of 30 minutes, and step 2) holding the packaging solution at 25(±5)°C Minimum 30 minutes. The lenses are then tested in the packaging solution. Lenses were packaged into vials containing 5-7 mL of borate buffered saline solution, capped, and sterilized at 120°C for 30 minutes. Dy...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
contact angleaaaaaaaaaa
number average molecular weightaaaaaaaaaa
molecular weightaaaaaaaaaa
Login to View More

Abstract

The present invention is a process for forming ophthalmic devices such as contact lenses, comprising at least one silicone containing component, at least one hydrophilic component, at least one hydrophilic polymer and at least one diluent with a Hansen solubility parameter of about 2 to about 7. The processing of the ophthalmic device may be done using only aqueous solutions.

Description

[0001] Cross References to Related Applications [0002] This application is a continuation-in-part of application serial number 10 / 938361, filed September 9, 2004, which is a continuation-in-part of application serial number 10 / 938361, filed September 6, 2002, which is now pending as US 6,822,016 divisional application. This application is also a continuation in part of application serial number 11 / 223464 filed on September 9, 2005, which was filed on September 6, 2002 and is now a divisional application of US 7,052,131 issued as 10 / 236,762, each The patent is incorporated herein by reference. field of invention [0003] The present invention relates to methods of forming molded articles, especially medical devices such as contact lenses. More particularly, the present invention relates to a new class of diluents that allow the formation of compatible blends (and finished products) comprising hydrophilic components, silicone-containing components and internal wetting agent...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G02B1/04C08L83/04A61L27/18
CPCG02B1/043B29D11/00134A61L27/18C08L83/04C08L51/085G02B1/04
Inventor J·D·福德D·扎尼尼K·阿尔泰姆
Owner JOHNSON & JOHNSON VISION CARE INC
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com