Bionic enzymatic product of animal medicament and application thereof

An enzymatic hydrolysis product and biomimetic enzymatic hydrolysis technology, applied in the field of biomimetic enzymatic hydrolysis products, can solve the problems of waste of medicinal materials, waste of medicinal materials, and reduction of curative effect.

Inactive Publication Date: 2010-02-17
BEIJING HERUN INNOVATION PHARMA TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional raw powder is taken directly. Only a small amount of macromolecular protein in the raw drug powder is decomposed in the gastrointestinal tract in the body and becomes small molecular oligopeptides to be absorbed. The interference of oral administration of other foods results in incomplete hydrolysis, less active ingre...

Method used

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  • Bionic enzymatic product of animal medicament and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0079] Take 500g of leech, crush it into fine powder, add 10 times the amount of water to homogenate, adjust the pH to 2.0, add 1% of the amount of leech pepsin, keep it at 40°C for 2 hours, adjust the pH to 8.0, add 1% of the amount of leech % trypsin was incubated at 50° C. for 4 hours, spray-dried, added an appropriate amount of starch, granulated, dried, sized, and filled into capsules.

Embodiment 2

[0081] Take 500g of ants, crush them into fine powder, add 10 times the amount of water to homogenate, adjust the pH to 2.0, add 2% pepsin of the amount of ants, keep it at 40°C for 2 hours, adjust the pH to 8.5, add 1.5% of the amount of ants % trypsin is incubated at 50° C. for 5 hours, spray-dried, added an appropriate amount of starch, granulated, dried, sized, and filled into capsules.

Embodiment 3

[0083] Take 500g of the ground beetle, crush it into fine powder, add 8 times the amount of water to homogenate, adjust the pH to 2.6, add 2% of the amount of the wood beetle with pepsin, incubate at 37°C for 3 hours, adjust the pH to 7.5, add the wood beetle A certain amount of 2% trypsin is incubated at 40° C. for 6 hours, spray-dried, added with an appropriate amount of microcrystalline cellulose, granulated, dried, sized, and compressed into tablets.

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PUM

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Abstract

The invention discloses a bionic enzymatic product of animal medicament and application thereof, which belong to the field of Chinese medicament. The bionic enzymatic product is characterized in thata bionic enzymatic method is adopted, and comprises the following steps: taking animal medicament; grinding the animal medicament into fine powders; adding water into the fine powders; evenly stirringthe mixture; under appropriate condition, performing heat preservation by using pepsin; performing heat preservation by using pancreatin or trypsase; and preparing obtained zymolyte into preparationsaccording to different preparation requirements. The product of the invention has good effects in the aspects of resisting hepatitis virus, reducing blood press and resisting cancer.

Description

technical field [0001] The invention relates to a biomimetic enzymatic hydrolysis product of animal medicine and its application in the aspects of anti-hepatitis virus, lowering blood pressure and anti-cancer. It belongs to the field of traditional Chinese medicine. technical background [0002] The application of animal traditional Chinese medicine has a very long history in our country. As early as more than 3,000 years ago, China began to utilize bees. The breeding of pearls and male bats was first seen in China, with a history of more than 2,000 years. my country's earliest herbal book "Shen Nong's Materia Medica" contains 365 kinds of medicines, including 65 kinds of animal medicines; according to incomplete statistics, there are about 160 kinds of animals in "Book of Songs", many of which are In addition, the "Shan Hai Jing" of the Spring and Autumn Period and the Warring States Period also recorded 67 kinds of medicinal animals; the "Shen Nong's Herbal Classic" of t...

Claims

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Application Information

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IPC IPC(8): A61K35/00A61K35/32A61K35/62A61K35/64A61P1/16A61P9/12A61P31/14A61P31/20A61P35/00C12P21/00
Inventor 刘国飞周小明
Owner BEIJING HERUN INNOVATION PHARMA TECH DEV
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