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Lactobacillus vaginal capsule and preparation method thereof

A technology of lactic acid bacteria and capsules, which is applied in capsule delivery, pharmaceutical formulations, medical raw materials derived from bacteria, etc., can solve problems such as unsatisfactory results, reduce psychological pressure and economic burden, reduce recurrence rate, and increase compliance.

Active Publication Date: 2012-06-20
XIAN ZHENGHAO BIOLOGICAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, the treatment measures for such diseases mainly use antimicrobial agents to kill pathogenic microorganisms in the vagina, but the effect is not ideal

Method used

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  • Lactobacillus vaginal capsule and preparation method thereof
  • Lactobacillus vaginal capsule and preparation method thereof

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Embodiment Construction

[0022] The lactic acid bacteria vaginal capsule of the present invention is a biological preparation of live bacteria. The prepared lactic acid bacteria vaginal capsule is composed of excipients and live Streptococcus enterococcus in powder form capsules. The live Streptococcus enterococcus is at least in each capsule Containing 25 million plants / g, the excipient is composed of calcium carbonate powder and medicinal starch, and its dosage is calcium carbonate powder: medicinal starch=1:1.

[0023] The lactic acid bacteria vaginal capsule of the present invention uses the treatment mechanism of "using bacteria to cure bacteria", without destroying the original number and function of probiotic bacteria in the vagina, and by improving and balancing the vaginal microecological environment, it can treat the disease caused by the disorder of the flora. Various vaginosis. The application of the invention overcomes many disadvantages of vaginal microecological imbalance, drug resistance,...

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Abstract

The invention discloses a lactobacillus vaginal capsule and a preparation method thereof. The prepared lactobacillus vaginal capsule is a powdered capsule composed of excipient and living enterostreptococcus, wherein one capsule contains at least 2.5 million strains per gram of living enterostreptococcus; and the excipient comprises calcium carbonate powder and medicinal starch in a ratio of 1:1.The experiments show that the lactobacillus vaginal capsule can fully supplement lactobacillus which is the most important material in vagina so as to inhibit the growth and propagation of bacteria and play the action of using bacteria to inhibit bacteria; the best advantage of the lactobacillus vaginal capsule is to overcome the problem that the abuse of antibiotics and related products results in that vaginitis repeatedly relapses so as to cause microecological imbalance, drug resistance, superinfection, side effect and the like, solve the problem that patients have symptoms but can not find pathogeny and the problems such as overdiagnosis, over-treatment and medication security of lactation and pregnant women, provide a new choice for prophylactic of healthy women and fill the blank ofthe medication for lactation and pregnant women.

Description

Technical field [0001] The invention relates to a microecological preparation, in particular to a lactic acid bacteria vaginal capsule and a preparation method thereof. Background technique [0002] There are a variety of normal microbial communities in the vagina of healthy women. They form a mutually restrictive, coordinated and dynamic vaginal microecological balance with the host and the environment. The main resident bacteria in the vagina include: lactic acid bacteria (live Streptococcus enterococcus), Staphylococcus epidermidis, Escherichia coli, Group B Streptococcus, Corynebacterium, Mycoplasma, Candida albicans, Bacteroides, etc., among which Lactobacillus (Live Streptococcus) It is the most important and most abundant resident bacteria in the vaginal flora, accounting for more than 95%. This lactic acid bacteria decomposes glycogen in vaginal mucosal epithelial cells to produce lactic acid to maintain a lower pH in the vagina (PH value is about 4.5), and pathogenic ba...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K47/36A61P15/02A61K35/74A61K35/744
Inventor 李小卫张慧君孙向东黄玉芹
Owner XIAN ZHENGHAO BIOLOGICAL PHARMA