Nanometer biological robot and application thereof
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- INSITUTE OF BIOPHYSICS CHINESE ACADEMY OF SCIENCES
- Publication Date
- 2010-06-23
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The invention belongs to the field of nano-biological new technology, and relates to the design, assembly and application of a light-driven nano-robot constructed by a rotary ATP motor and in assisting drug diffusion (thrombolysis). Background technique
[0002] Traditional thrombolytic therapy methods include drug thrombolysis and device-assisted thrombolysis. In the rescue treatment of acute myocardial infarction, thrombolytic therapy is an effective method to quickly restore myocardial blood flow, and early use of thrombolytic therapy can reduce the mortality rate of patients with acute myocardial infarction by 30% [FEBS.Lett.2005, 579 (15 ): 3303-3309]. Recombinant tissue plasminogen activator (rt-PA) is currently the most effective thrombolytic drug. The main advantage of this drug is that it has a high affinity with fibrin and fast thrombolytic speed; the disadvantage is that it is easily cleared by the liver. , short half-life (4 minutes to 5 ...