The invention discloses a multi-purpose rehabilitation chair realizing synchronous movement of the hands and the feet and a use method of the multi-purpose rehabilitation chair. For the existing auxiliary appliance, the mode switch between sitting exercising and standing exercising can not be realized. The multi-purpose rehabilitation chair realizing synchronous movement of the hands and the feetcomprises a chair body, a seat cushion plate, a backrest plate, a standing auxiliary mechanism, a drive mechanism, arm stretching mechanisms and foot lifting mechanisms, wherein the standing auxiliarymechanism comprises an electric push rod, a sliding plate, a fixed plate, a first connecting plate, a second connecting plate, a first hinge plate group and a second hinge plate group. The drive mechanism comprises a motor, handle crankshaft assemblies, foot-lifting crankshaft assemblies, a first encoder, a second encoder, a third encoder, a first connecting rod, a second connecting rod, a thirdconnecting rod, a first slider, a second slider and a fourth connecting rod. Each foot lifting mechanism comprises a pedal assembly and a third hinge plate group. For the multi-purpose rehabilitationchair, the alternate mode switch between sitting exercising and standing exercising can be realized, meanwhile, after mode switch, the relative position of the upper half body of a user and two handles does not change.