Smoke exposure device used for establishing chronic obstructive pulmonary disease model

A chronic obstructive and smog technology, applied in the field of medical basic research experimental equipment, can solve the problems of high price and difficulty in popularization and application, and achieve the effects of low cost, avoiding suffocation and death, and simple structure

Inactive Publication Date: 2010-11-17
ZHEJIANG UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

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  • Smoke exposure device used for establishing chronic obstructive pulmonary disease model
  • Smoke exposure device used for establishing chronic obstructive pulmonary disease model
  • Smoke exposure device used for establishing chronic obstructive pulmonary disease model

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Experimental program
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Embodiment Construction

[0014] exist figure 1 Among them, the flow regulating device 7 includes a smoke inlet pipe 1 , an air inlet pipe 4 , a smoke outlet pipe 3 , an air outlet pipe 6 , a smoke flow regulator 2 and an air flow regulator 5 . The two ends of the smoke flow regulator 2 are respectively connected to the smoke inlet pipe 1 and the smoke outlet pipe 3, and the two ends of the air flow regulator 5 are connected to the air inlet pipe 4 and the air outlet pipe 6 respectively, so that the smoke flow and its connection with the smoke flow can be accurately regulated. The proportion of air is convenient for quantitative analysis, thereby improving the stability, reliability and repeatability of the experiment, and the effect is remarkable. In addition, the smoke outlet pipe 3 , the air outlet pipe 6 and the air guide tube 8 communicate with each other, the air guide tube 8 communicates with the airtight box 11 , and the air guide tube 8 is placed in the pump tube bed 10 of the peristaltic pump...

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Abstract

The invention discloses a smoke exposure device used for establishing a chronic obstructive pulmonary disease model. The smoke exposure device mainly comprises a flow regulating device, a peristaltic pump and a closed box, wherein the flow regulating device comprises a smoke inlet pipe, an air inlet pipe, a smoke outlet pipe, an air outlet pipe, a smoke flow regulator and an air flow regulator; the smoke flow regulator is communicated with the smoke inlet pipe and the smoke outlet pipe respectively; the air flow regulator is communicated with the air inlet pipe and the air outlet pipe respectively; the smoke outlet pipe, the air outlet pipe and an air duct are communicated with one another; and the air duct is communicated with the closed box and is arranged inside a pump bed of the peristaltic pump. The smoke exposure device has the advantages of precisely regulating the smoke flow and the ratio of the smoke flow to air, facilitating quantitative analysis, improving the stability, reliability and repeatability of an experiment, and effectively avoiding the suffocation death of experimental animals, the cigarette smoke inhalation of experiment operators and atmospheric pollution, along with simple structure, convenient manufacturing and low cost.

Description

technical field [0001] The invention relates to a smoke exposure device for establishing a model of chronic obstructive pulmonary disease, which belongs to the field of medical basic research experimental equipment. Background technique [0002] It has been clear that smoking is the most important pathogenic factor of human chronic obstructive pulmonary disease. Simulating the pathogenesis process, the animal model of emphysema induced by passive smoking of experimental animals through smoke exposure has been recognized by many researchers and is widely used in the research of the pathogenesis and clinical prevention and treatment of COPD. [0003] At present, domestic researchers mostly use fumigation devices to build animal COPD models. The reported methods are similar, which can be briefly described as follows: separate the upper and lower parts of the airtight container with a shelf with holes, and put the experimental animals on the shelf. , and then light a cigarette ...

Claims

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Application Information

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IPC IPC(8): A61D7/00
Inventor 李和权姚一楠高润娣曹婕陆国华王晴周建英
Owner ZHEJIANG UNIV
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