External ointment matrix and preparation method thereof

Abstract

The invention relates to an external ointment matrix and a preparation method thereof. The external ointment matrix is characterized by consisting of the following raw materials in part by weight: 900 to 1,100 parts of alseodaphne hainanensis ointment, 90 to 110 parts of medical pressure-sensitive adhesive and 29 to 31 parts of azone. The preparation method comprises the following steps of: respectively putting the alseodaphne hainanensis ointment and the medical pressure-sensitive adhesive in the raw materials into two containers and heating for dissolving at the temperature of between 180 and 200 DEG C; pouring the fully dissolved pressure-sensitive adhesive into the container containing the fully dissolved alseodaphne hainanensis ointment, continuing to heat and stirring continuously, so that the alseodaphne hainanensis ointment and the pressure-sensitive adhesive are dissolved and mixed fully to prepare ointment for later use; continuing to heat the mixed ointment over fire, stopping heating until the temperature in the container reaches between 180 and 220 DEG C for cooling; and adding the azone into the raw materials into the ointment of which the temperature is between 150 and 180 DEG C, stirring fully and uniformly to obtain the ointment matrix. The permeability of medicaments can be promoted due to the selection of the medical pressure-sensitive adhesive made of a high molecular nanometer material, so the external ointment has numerous advantages of the conventional ointment with a hard matrix, enables the ointment matrix to be soft, allows patients to apply conveniently, adaptively and comfortably, and is favorable for absorbing the medicaments by subcutaneous deep tissue.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to an external ointment base and a preparation method thereof. Background technique [0002] Traditional plaster bases for external use mainly include: ointment paste, rosin paste, wax paste and other shaped plaster bases. Difficulties. At the same time, the hard plaster patient will have some uncomfortable or uncomfortable sensations. Furthermore hard matrix plaster is unfavorable for the decomposition of drug ion, poor to the permeability of skin, thereby unfavorable for subcutaneous deep tissue (as muscle, fascia, bone, and bone connection etc.) to the absorption of medicine. Also have because the composition of hard matrix plaster is more complicated so the incidence rate of skin allergy is also higher. Contents of the invention [0003] The purpose of the present invention is to aim at the defects of the existing hard matrix plasters, and t...

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to aim at the defects of the existing hard matrix plasters, and to improve the traditional hard matrix plasters in combination with modern nanotechnology, to provide people with a method that not only inherits many advantages and advantages of the traditional hard matrix plasters, but also makes the plaster matrix become The plaster base for external use is soft, convenient, adaptable and comfortable for patients to apply, and is beneficial to the absorption of drugs by subcutaneous deep tissue and its preparation method