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Traditional Chinese medicine having function of tonifying kidney, invigorating blood circulation and relieving pain, preparation method and quality specification thereof

A technology of kidney-tonifying and traditional Chinese medicine capsules, which can solve the problems of low controllability, slow onset of effect, and unfavorable preparation of capsules, and achieve the effect of controllable process and fast absorption speed when applied to unfavorable activities

Inactive Publication Date: 2011-01-26
秦皇岛润青制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

National Chinese patent medicine standard WS-10154 (ZD-0154)-2002 discloses a kind of Jingkang Tablet for the treatment of cervical spondylosis caused by kidney deficiency and blood stasis. hot), uncaria, kudzu root, notoginseng, radish (fried), used for the treatment of the above diseases, and achieved certain curative effect, but the onset of effect is slow and the disintegration time is long
Chinese patent 200510032466.0 discloses dosage forms such as soft capsules, micropills, and capsules. This document still has the following deficiencies: 1. It is unfavorable to prepare capsules by mixing and decocting 9 medicinal materials.
2. There are no specific parameters such as the amount of extract, and the controllability is low

Method used

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  • Traditional Chinese medicine having function of tonifying kidney, invigorating blood circulation and relieving pain, preparation method and quality specification thereof
  • Traditional Chinese medicine having function of tonifying kidney, invigorating blood circulation and relieving pain, preparation method and quality specification thereof
  • Traditional Chinese medicine having function of tonifying kidney, invigorating blood circulation and relieving pain, preparation method and quality specification thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0162] Embodiment 1, capsule of the present invention

[0163] Rehmannia glutinosa 204.5g Polygonum multiflorum 272.8g Eucommia 136.4g

[0164] Deerbite grass 136.4g Drynaria rhizome (hot) 136.4g Uncaria 100g

[0165] Pueraria root 100g Panax notoginseng 50g Raisin seed (stir-fried) 86.2g

[0166] [Preparation method] Take 25g of the above nine medicinal materials and crush them into fine powder; add the remaining eight ingredients such as Sanqi and rehmannia glutinosa, add water to decoct twice, add 10 times the amount of water to decoct for 3 hours for the first time, and decoct for the second time Add 8 times the amount of water and decoct for 2 hours, combine the decoction, filter, and concentrate the filtrate to a thick paste with a relative density of 1.30-1.35 (80°C), mix it with the above powder, dry it under vacuum at 70°C, and crush the dry paste through 100 mesh Sieve, mix with an appropriate amount of starch, use 85% ethanol as a wetting agent to make a soft mate...

Embodiment 2

[0167] Embodiment 2, capsules of the present invention

[0168] Rehmannia glutinosa 200g Polygonum multiflorum 200g Eucommia 150g

[0169] 200g deer title grass Drynaria rhizome (hot) 150g Uncaria 200g

[0170] Pueraria root 200g Panax notoginseng 200g Raisin seed (stir-fried) 200g.

[0171] [Preparation method] Take 25g of the above nine medicinal materials and crush them into fine powder; add the remaining eight ingredients such as Sanqi and Rehmannia glutinosa, add water to decoct twice, add 12 times the amount of water to decoct for 2 hours for the first time, and decoct for the second time Add 10 times the amount of water and decoct for 1 hour, combine the decoction, filter, concentrate the filtrate to a thick paste with a relative density of 1.30-1.35 (80°C), mix it with the above powder, dry it under vacuum at 70°C, and crush the dry paste through 100 mesh Sieve, mix with an appropriate amount of starch, use 85% ethanol as a wetting agent to make a soft material, gran...

Embodiment 3

[0172] Embodiment 3, capsules of the present invention

[0173] Rehmannia glutinosa 200g Polygonum multiflorum 200g Eucommia 150g

[0174] 200g Rhizoma Rhizoma Drynariae (hot) 150g Uncaria 200 parts Panax notoginseng 200g.

[0175] [Preparation method] Take 25g of the above nine medicinal materials and grind them into fine powder; add the remaining eight ingredients such as Sanqi and Rehmannia glutinosa, add water to decoct twice, add 8 times the amount of water for the first time and decoct for 4 hours, and the second time Add 6 times the amount of water and decoct for 3 hours, combine the decoction, filter, and concentrate the filtrate to a thick paste with a relative density of 1.30-1.35 (80°C), mix it with the above powder, dry it under vacuum at 70°C, and crush the dry paste through 100 mesh Sieve, mix with an appropriate amount of starch, use 85% ethanol as a wetting agent to make a soft material, granulate with a 20-mesh sieve, dry at 50°C-60°C, granulate with a 20-mes...

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Abstract

The invention discloses a capsule for treating neck swelled pain, inconvenient motion, swirl and tinnitus, a preparation method thereof and a detection method. The medicine comprises a capsule wrapper and inner fillers, wherein the inner filler of each capsule contains 0.26 to 0.29g active ingredients and medical auxiliary materials. The active ingredients are prepared by using a certain weight part of prepared rehmannia root, Polygonum multiflorum, Eucommia ulmoides, pyrola, Rhizoma Drynariae, uncaria and pseudo-ginseng. The medical auxiliary materials contain starch. The clinical test proved that the efficiency of the test group using the sample of the invention is 98.85% while the efficiency of a comparison group is 96.92%. Relative to use clear paste as medicine with uncertain concentration ratio and drying condition, the technique of the invention is more controllable by using dry powder as medicine with the best concentration ratio and specified drying condition.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a medicine for treating neck pain, numbness, unfavorable movement, dizziness and tinnitus, a preparation method of the medicine, and a detection method. Background technique [0002] Cervical spondylosis, also known as cervical syndrome, is a general term for cervical osteoarthritis, hypertrophic spondylitis, cervical nerve root syndrome, and cervical disc herniation. It is a disease based on degenerative pathological changes, mainly due to long-term strain of the cervical spine. , Bone hyperplasia, or intervertebral disc prolapse, ligament thickening, resulting in cervical spinal cord, nerve root or vertebral artery compression, a series of clinical syndromes of dysfunction. National Chinese patent medicine standard WS-10154 (ZD-0154)-2002 discloses a kind of Jingkang Tablet for the treatment of cervical spondylosis caused by kidney deficiency and blood stasis. hot), u...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/48G01N30/90A61P13/12A61P7/00A61P29/00A61P19/08
Inventor 佟雪松
Owner 秦皇岛润青制药有限公司
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