Chitosan hemostatic sponge made from maggot shells as well as preparation method and application thereof

A technology of chitosan and maggot shells, which is applied in medical science, absorbent pads, bandages, etc., can solve the problems of raw material quality control and production process reproducibility, and achieve the prevention of wound infection, selective antibacterial cell proliferation, and promotion of The effect of cell proliferation
CN101974170AActive Publication Date: 2011-02-16FIELD OPERATION BLOOD TRANSFUSION INST OF PLA SCI ACAD OF MILITARY

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
FIELD OPERATION BLOOD TRANSFUSION INST OF PLA SCI ACAD OF MILITARY
Publication Date
2011-02-16

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Abstract

The invention discloses a chitosan hemostatic sponge made from maggot shells as well as a preparation method and application thereof. The chitosan hemostatic sponge is obtained by carrying out the following steps of: pulverizing cleaned and dried maggot shells; removing metal ions with a hydrochloric acid solution; removing protein with a sodium hydroxide solution; decoloring with a hydrogen peroxide solution; carrying out gradient deacetylation with the sodium hydroxide solution; drying to obtain powder; then dissolving the powder into a dilute acetic acid solution; freeze drying; and sterilizing. The product can effectively activate partial blood platelets, adsorb erythrocytes, promote the generation of partial thrombase, exert quick and stable hemostatic activity when the product is adhered to a partial tissue wound, have the effects of selective antibiosis and cell proliferation promotion and favorable effects of controlling moderate traumatic hemorrhage and tissue organ diffuse surface hemorrhage, can be suitable for external emergency treatment of traumatic hemorrhage, particularly suitable for implantation hemostasis in a surgery, and also has the functions of preventing wound infection of a wound surface and promoting healing of the wound surface.
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Description

technical field

[0001] The invention belongs to the field of medical hemostatic materials, and relates to a chitosan hemostatic sponge derived from fly maggot shells and a preparation method thereof, in particular to a hemostatic sponge capable of rapid hemostasis and various hemostatic mechanisms, which can be used for intraoperative implantation hemostasis and prevent wounds Wound infection, chitosan derived from fly maggot shell for promoting wound healing, its hemostatic sponge and its preparation method. Background technique

[0002] Bleeding is the leading cause of death from all types of trauma. Rapid hemostasis is an important part of various operations and trauma first aid. Local hemostatic materials are the first choice for pre-hospital and intraoperative emergency hemostasis due to their simplicity and rapidity in the emergency treatment of surgery and sudden accidents. The research and development of ideal local hemostatic materials has always been a hot spot a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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