Method for manufacturing micro-pipeline stent with nano structure on inner wall

Abstract

The invention discloses a method for manufacturing a micro-pipeline stent with a nano structure on the inner wall. The micro-pipeline stent with a nano structure on the inner wall is manufactured by the steps of manufacturing a template, preparing a macromolecular solution, casting, stripping, ordering for bonding, and the like through combining a thermal fluid reflux and plasma induction coupling technology; and the micro-pipeline stent with a nano structure on the inner wall has the advantages of favorable biocompatibility, biodegradability and biological absorbability and novel and unique structure, is beneficial to the growth and spreading of cells, can improve the function of the stent in a living body and maintain the normal metabolism of the cells and has wide application prospect in the fields of transportation of nutrient substances, exchange of metabolic products, a culture base plate of active substances, a stent material of sealed space, tissue engineering stent materials, and the like.

Description

technical field [0001] The invention relates to a preparation method of a micro-pipe support, more specifically, a preparation method of a micro-pipe support with a nanostructure on the inner wall. Background technique [0002] Over the past few decades, the intersection of extracellular scaffold engineering, cytology, and bioactive substances has led to artificially cultured tissues in the laboratory, in which cells are often cultured in three-dimensional tissue-degradable These scaffolds have many uses, such as substrates for cell adhesion and transfer, nutrient exchange, immobilization or retention of cells and bioactive factors. However, tissue engineering scaffolds have always faced a challenge. It cannot exchange nutrients and metabolites like real microvessels, so that cultured cells cannot normally obtain enough nutrients and oxygen to perform normal functions. A possible solution to this problem is to provide an artificial micro-plumbing system to support normal me...

AI Technical Summary

Problems solved by technology

However, the existing nanostructured polylactide scaffold materials are limited to scaffolds applied in open spaces, and it is still challenging to fabricate closed scaffolds (such as microvascular stents) and microchannels with nanostructures on the inner wall.