33results about How to "Good bioabsorbability" patented technology

The invention relates to a gelatin-based micro-nanofiber membrane material, preparation method and utilization thereof and an electrostatic spinning machine used for processing the gelatin-based micro-nanofiber membrane material. The gelatin-based micro-nanofiber membrane material is composed of micro-nanofiber composed of 2-98 wt% of gelatin, 2-98 wt% of other biomolecule, 0-40 wt% of additive, 0-40 wt% of emulgator and 0-40 wt% of medicine. According to the arrangement, the conventional electrostatic spinning machine is modified, and a spiral-plate electrostatic spinning machine, a spring-type electrostatic spinning machine, a drum-type electrostatic spinning machine, a screw-type electrostatic spinning machine, a rotary-shaft electrostatic spinning machine or a gear-type electrostatic spinning machine used for processing the gelatin-based micro-nanofiber membrane material is achieved.

A coenzyme Q10-containing composition comprising a coenzyme Q10 and a hydrophilic fatty acid ester of a polyhydric alcohol; a coenzyme Q10-containing composition comprising a coenzyme Q10, a lipophilic fatty acid ester of a polyhydric alcohol and a hydrophilic fatty acid ester of a polyhydric alcohol; and a food or beverage comprising the coenzyme Q10-containing composition as defined above.

The invention relates to a fiber compact double-layered composite film, which consists of two layers including a smooth compact film and a nano fiber film. The two films are combined tightly and cannot be separated. A preparation method of the fiber compact double-layered composite film includes mixing and dissolving polylactic-co-glycolic acid and polylactide-b-polyethylene glycol into N, N-dimethylformamide or acetone or mixture of the N, N- dimethylformamide and the acetone so as to obtain uniform polymer solution; then knifing the polymer solution on a roller or realizing electrostatic spinning on the roller and then drying the roller after heating the roller so as to obtain the compact film layer; and finally realizing electrostatic spinning on the compact film to obtain a fiber film layer, and accordingly obtaining the fiber compact double-layered composite film. The fiber compact double-layered composite film has excellent biocompatibility, biodegradation and biological absorption, and simultaneously has the advantages of light weight and softness. Besides, mechanical property and degradation period of the fiber compact double-layered composite film can be flexibly adjusted according to service needs.

The invention relates to a biodegradable graphene oxide biocomposite fibrous membrane and a preparation method and uses thereof. The composite fibrous membrane comprises biodegradable graphene oxide biocomposite fibers, each fiber has an outer layer consisting of graphene oxide-biodegradable polymer nanofibers and an inner layer consisting of sodium alginate/polyvinyl alcohol nanocomposite fibers. The biodegradable graphene oxide biocomposite fibrous membrane of the invention has the advantages of good biocompatibility, biodegradability, swellability, bacteriostasis and good mechanical properties and chemical stability.

An object of the present invention is to provide an internal composition capable of exerting various physiological functions such as a brain-function improving function. That is, the present invention provides an internal composition including docosahexaenoic acid and capsanthin, or docosahexaenoic acid, capsanthin, lutein, and zeaxanthin as active ingredients.

A low-molecular-weight hyaluronic acid and/or its salt has an average molecular weight of 5000 to 20,000, and has a molecular weight distribution in which the proportion of components having a molecular weight of 10,000 or less is 40 wt % or more and the proportion of components having a molecular weight of 50,000 or more is 5 wt % or less.

Provided is a composition for hot melt extrusion including a drug and hypromellose acetate succinate (HPMCAS) having a hydroxypropoxy molar substitution of 0.40 or more and a mole ratio of an acetyl group to a succinyl group of less than 1.6. Further, provided is a method for producing a hot melt extrudate including the step of hot melt-extruding a composition for hot melt extrusion including a drug and hypromellose acetate succinate having a molar hydroxypropoxy substitution of 0.40 or more and a mole ratio of an acetyl group to a succinyl group of less than 1.6, at a hot melt temperature of not lower than a melting temperature of the hypromellose acetate succinate or of not lower than a temperature at which both the hypromellose acetate succinate and the drug are melted.

The invention belongs to the technical field of biomaterials, and particularly relates to a preparation method and an application of a high-biocompatibility biodegradable bone filling material. The bone filling material is composed of polyurethane urea having phosphorylcholine at the end of a flexible side chain, and polyurethane urea is prepared from a single-ended dihydroxy polyethylene glycol phosphorylcholine compound, double-ended hydroxypolydioxanone and L-lysine diisocyanate-1,4-dibutyl diamine-L-lysine diisocyanate. The phosphorylcholine group located at the end of the flexible polyethylene glycol side chain is easily enriched on the surface of the material in order to greatly improve the hydrophilicity of the material, hinder the deposition of platelets and proteins and avoid theformation of thrombus, so the material has high biocompatibility, solves the problems of low biocompatibility and poor mechanical performances of polyurethane with the side chain simply being polyethylene glycol or phosphorylcholine, especially used a long-term implant material, in the biomedical field, and has widened applications in fields of tissue engineering, drug controlled release, gene therapy and cosmetics.

The present invention relates to a mineral composition, characterized in that the mineral composition comprises 100 parts by weight of a metal salt having a solubility product in water at 25° C. of 1.0×10⁻⁷ or less and 0.5 to 50 parts by weight of an emulsifier having an HLB of 6 to 10, wherein the metal salt comprises fine particles having an average particle size of 0.05 to 1 μm.

The invention relates to a preparation method of a cortex phellodendri composite biological glass tissue repair material, and belongs to the field of biomedical materials, wherein the preparation method comprises: preparing a cortex phellodendri extraction liquid, preparing a polylactic acid solution, preparing a biological glass solution, and carrying out electrospinning to obtain the repair material. According to the present invention, the cortex phellodendri has the antibacterial effect, the polylactic acid can improve the mechanical property of the material, and the biological glass can improve the pharmaceutical property of the material; and the prepared tissue repair material has advantages of good mechanical property, good tissue repair property, and good drug adhesion property.

An antiadhesive material that is excellent in biocompatibility and bioabsorbability, as well as excellent strength in suturing and bonding, is provided. A reinforcing material 12 made of a biodegradable polymer is placed in a gelatin solution so that the reinforcing material 12 is impregnated with the solution, and the gelatin is caused to gelate and dried. By so doing, an antiadhesive material in which a gelatin film 11 and the reinforcing material12 are integrated is obtained. The reinforcing material 12 preferably is arranged in a portion of the gelatin film 11 to be subjected to suturing, and preferably is arranged along a periphery of the gelatin film 11. The gelatin film 11 preferably is a cross-linked gelatin film, and the reinforcing material 12 preferably is a nonwoven fabric.

The present disclosure provides a micron fish oil composition and a method for preparing the micron fish oil composition. The method includes mixing a composite plant colloid with a fish oil and subjecting to an emulsification treatment to obtain an emulsion; and homogenizing the emulsion at a pressure of 300 bar to 350 bar to obtain the micron fish oil composition. The present disclosure also provides a method for enhancing bioabsorbability and bioavailability in a subject, including administering to the subject in need thereof a food product including an effective amount of the micron fish oil composition.

Provided is a tyrosine formulation excellent in bioabsorbability of tyrosine when ingested orally. An oral formulation with improved bioabsorbability of tyrosine, including glycyltyrosine or a salt thereof or a solvate thereof.

The invention discloses a method for preparing a purslane composite bioglass traditional Chinese medicine repair material and belongs to the field of biological medicine materials. The method comprises the following steps: preparing a purslane extracting solution, preparing a polyphosphazene solution, preparing a bioglass solution, and performing electrostatic spinning, thereby obtaining the repair material. The purslane contains unique bioactive components and is capable of enhancing the activity of human epithelial cells; the polyphosphazene has excellent biodegradability, bioabsorbability and biocompatibility and is capable of improving mechanical property of the material, and the bioglass is capable of improving the medicinal properties of the material. The repair material prepared by the invention has excellent mechanical property, tissue repair performance and drug adhesiveness.