Method for extracting esculetin from herba violae
A technology of escin and viola, which is applied in the direction of organic chemistry, etc., can solve the problems that are not suitable for industrial production, and achieve good results
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0021] Crush the raw material of Viola dichotoma, take 1kg, add 10kg of 60% ethanol to reflux and extract twice, extract for 2 hours each time, filter to obtain the extract, recover the ethanol under reduced pressure, add HZ806 (resin 500ml) to the large pores after diluting the concentrated solution with water The resin column is adsorbed. After the adsorption is completed, the resin column is washed with water until it is sugar-free, and then 3L of 50% ethanol is taken to elute the active ingredient. The eluent is recovered from the ethanol, and the pH is adjusted to 1 with 10% hydrochloric acid solution while it is still hot. The precipitate is filtered out. Ethyl acetate was refluxed to dissolve, peracid alumina short column (alumina 120-300 mesh, dosage 80g), the column liquid was recovered to 1 / 5 volume and placed to crystallize, the crystal was filtered out, 60% ethanol was refluxed and dissolved, and then concentrated to 1 / 3 volume crystallized twice, the crystals were...
Embodiment 2
[0023] Crush the raw material of Viola dichotoma, take 1 kg, add 7 kg of 90% ethanol to reflux extraction for 3 times, extract for 1 hour each time, filter, extract the ethanol under reduced pressure, dilute the concentrated solution with water, add LSA-7 (resin 600ml) Porous resin column adsorption, after the adsorption is completed, first wash the resin column with water until it is sugar-free, then take 2.4L of 80% ethanol to elute the active ingredient, recover the ethanol from the eluent, adjust the pH to 3 with 10% hydrochloric acid solution while it is hot, and place the precipitate, filter the precipitate out, ethyl acetate reflux to dissolve, peracid aluminum oxide conventional column (alumina 120-300 mesh, dosage 100g), the column liquid is recovered to 1 / 6 volume and placed to crystallize, and the crystal is filtered out, and after 90% ethanol reflux dissolves Concentrate to 1 / 5 volume of crystals, filter out the crystals, and dry to obtain 1.8 g of pale yellow cryst...
Embodiment 3
[0025] Take Viola dichotoma raw material, take 10kg, put it into a 500L stainless steel extraction tank, add 100kg of 80% ethanol to reflux extraction twice, extract for 2 hours each time, filter, extract the extract under reduced pressure to recover ethanol, add ADS- 17 (resin 5L) macroporous resin column adsorption, after the adsorption is completed, first wash the resin column with water until it is sugar-free, then take 25L of 65% ethanol to elute the active ingredients, recover the ethanol from the eluent, and adjust the pH1 with 10% hydrochloric acid solution while it is hot Precipitate, precipitate is filtered out, ethyl acetate is refluxed to dissolve, peracid alumina conventional column (alumina 120-300 mesh, dosage 1kg), the column liquid is recovered to 1 / 4 volume and placed for crystallization, and the crystallization is filtered out, 80 % ethanol was refluxed to dissolve, concentrated to 1 / 3 volume and crystallized twice, the crystals were filtered off, and dried t...
PUM
Property | Measurement | Unit |
---|---|---|
particle size | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com