Traditional Chinese medicine preparation for treating liver cancer and preparation method thereof

A traditional Chinese medicine preparation and a technology for treating liver cancer, which are applied in pharmaceutical formulations, medical preparations containing active ingredients, and drug combinations, etc., can solve the problems of traditional Chinese medicine preparations and measures that do not appear to have therapeutic effects on liver cancer, and achieve the enhancement of immune function and side effects of the body. Small, the effect of keeping the whole body in good condition

Inactive Publication Date: 2011-06-01
李秀举
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] But so far, there have not been Chinese medicines and measures that have a very satisfactory therapeutic effect on liver cancer at home and abroad.

Method used

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  • Traditional Chinese medicine preparation for treating liver cancer and preparation method thereof
  • Traditional Chinese medicine preparation for treating liver cancer and preparation method thereof
  • Traditional Chinese medicine preparation for treating liver cancer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0058] The preparation method of the enema of the present invention comprises: Acanthopanax 1500g, Hedyotis diffusa 1500g, Astragalus 1500g, Garcinia cambogia 1500g, Ligustrum lucidum 1500g, Atractylodes macrocephala 1500g, Shouwu 1500g, capillary wormwood 1500g, turmeric 1500g, Prunella vulgaris 1500g, Polyporus 1500g, Schisandra 1500g, Curcuma 1500g, Poria 1500g, Eclipta 1500g, Salvia 1500g, Paeoniae Alba 1500g, Scutellaria barbata 1500g, Scutellaria baicalensis 1500g, Epimedium 1500g, Buad 150g, Scorpion 150g. Add 5-10 times the amount of 60-90% ethanol to soak for 1-2 hours, extract twice; heat and extract for 1-2 hours, extract the active ingredient, concentrate it into a liquid paste, and become component 1; soak the remaining medicinal residues in water for 0.5 -1.5 hours, extract twice, 1-2 hours each time, combine the extracts, filter, concentrate, filter through 80-160 mesh and concentrate under reduced pressure to concentrate the filtrate with a relative density of 1...

experiment example 3

[0076] Experimental example 3: Cumulative toxicity test:

[0077] Chinese medicine preparation oral administration capsule of the present invention is to mice by 7.69,19.18 and 43.21g crude drug / kg continuous medication 15 weeks (1.0ml / 100g body weight, every day 2 times) and after drug withdrawal 3 weeks, the result shows: Chinese medicine preparation of the present invention The hair, behavior, defecation, body weight, organ weight, blood picture, liver and kidney function, blood sugar, blood lipid and other indicators of the rats were not significantly affected. After 3 weeks of drug withdrawal, there was no significant change in the organs of the rats. It shows that the oral capsule of the traditional Chinese medicine preparation of the present invention has little toxicity to rats after long-term administration, and there is no abnormal reaction after drug withdrawal, so the application is safe.

[0078] Skin and in vivo irritation test:

[0079] 1. get the rabbit to sh...

experiment example 1

[0083] Experimental example 1 the influence of Chinese medicine preparation of the present invention on S180 sarcoma transplantation tumor suppression rate

[0084] Experimental method: Extract the ascites cancer cell suspension grown in the peritoneal cavity of KM mice for 8 days under sterile conditions, dilute the cancer cell suspension and sterilized saline at 1:3, and take 50 KM mice (provided by the Department of Biology, Shandong University) Cultivate), inoculate 0.2ml of diluted cancer cell suspension subcutaneously in the armpit. After 24 hours, they were randomly divided into 7 groups, i.e. model group, 5-Fu group (25mg / kg) and the present invention 1, 2, 3 groups (1mg / kg, 4mg / kg, 16mg / kg), 10 in every group, respectively The corresponding drugs were given by intragastric administration (the model group was given an equal volume of distilled water by intragastric administration), and the mice were sacrificed 8 days later, the tumors were stripped, weighed, and the tu...

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Abstract

The invention provides a traditional Chinese medicine preparation for treating liver cancer, comprising the following raw medicines in parts by weight: 10-20 parts of acanthopanax, 10-20 parts of oldenlandia diffusa, 10-20 parts of radix astragali, 10-20 parts of cambogia, 10-20 parts of glossy privet fruit, 10-20 parts of white atractylodes rhizome, 10-20 parts of radix polygoni multiflori preparata, 10-20 parts of oriental wormwood, 10-20 parts of turmeric, 10-20 parts of selfheal, 10-20 parts of umbellate pore fungus, 10-20 parts of magnolia vine fruit, 10-20 parts of curcuma zedoary, 10-20 parts of tuckahoe, 10-20 parts of eclipta, 10-20 parts of root of red-rooted salvia, 10-20 parts of white peony root, 10-20 parts of barbed skullcap herb, 10-20 parts of baical skullcap root, 10-20 parts of epimedium, 1-10 parts of toad venom and 1-10 parts of scorpion. The traditional Chinese medicine preparation for treating liver cancer has the beneficial effects of prolonging the life time of inoperable patients, playing an adjuvant treating effect on patients treated mainly by operation, radiation treatment and chemo-treatment, and having certain curative effects on liver cancer-specific backgrounds of liver diseases such as hepatitis and liver cirrhosis.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals and a preparation method thereof, in particular to a traditional Chinese medicine preparation for treating liver cancer and a preparation method thereof. Background technique [0002] Primary liver cancer refers to the tumor of liver cells or intrahepatic bile duct cells. It is a highly malignant type of cancer. Clinically, it is characterized by progressive enlargement of the liver and pain, jaundice, fever, ascites, hemorrhage, nail Positive fetoprotein is the main manifestation. This disease is more common in China. The incidence rate is higher in East China and South China. The incidence rate in Asia and Africa is significantly higher than other regions in the world. The age of ~50 is more, and the male to female ratio is 4 to 7:1. Because the disease develops rapidly, the condition is complicated, and the treatment effect is poor, it is ex...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P35/00A61K35/56A61K35/64A61K35/646A61K35/65
Inventor 李秀举
Owner 李秀举
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