Precursor liposome of propolis flavone and preparation method thereof

Abstract

The invention relates to a precursor liposome of propolis flavone and a preparation method thereof. The method is characterized by comprising the following steps of: preparing a nanometer liposome suspension of the propolis flavone by a reverse-phase evaporation method, and freeze drying the nanometer liposome suspension of the propolis flavone to prepare the precursor liposome of the propolis flavone; and preparing a nanometer liposome of the propolis flavone with Tween 80 by taking the propolis flavone as cores and lecithin and cholesterol as membranes, and freeze drying the prepared nanometer liposome of the propolis flavone by the reverse-phase evaporation method to obtain the precursor liposome of the propolis flavone. Due to the adoption of the technical scheme, the stability of the propolis flavone in a strongly-acidic system of gastric acid can be enhanced to improve biological availability and achieve better health-care effect. The precursor liposome of the propolis flavone prepared by the freeze drying method can be convenient to store and convey and also can be applied in wide food systems.

Description

technical field

[0001] The invention belongs to the technical field of bee product processing technology, and in particular relates to a propolis flavone proliposome and a preparation method thereof. Background technique

[0002] Propolis is a kind of colloidal solid with aromatic flavor, which is processed by honey bees from the resin collected from plant buds or broken parts of tree trunks, and mixed with the secretions of their mandibular glands and beeswax. Propolis has the functions of antibacterial, anti-corrosion, anti-virus, anti-oxidation, promoting blood circulation and removing stasis, softening blood vessels, lowering blood fat, anti-tumor, enhancing human immunity, and promoting tissue regeneration;

[0003] The composition of propolis is quite complex, among which flavonoids are the main active substances. Propolis has the reputation of "treasure house of flavonoids". The flavonoids that have been isolated and identified from propolis include chrysin, apigenin...