A New Technology for Drying Soft Capsules

A soft capsule and new technology, applied in the field of soft capsule drug drying, can solve problems such as uneven drying of products, contamination of qualified products on the conveyor belt, uneven drying air supply, etc.

Inactive Publication Date: 2011-12-21
贵州地道药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the crawler drying system cannot dehumidify alone; it has a humidification effect on other air-conditioning systems and destroys the temperature and humidity control balance of other systems
[0006] 2. The drying efficiency is low, the time is long, the labor intensity of the workers is high, and the working environment is harsh. Since the relative humidity in the drying area cannot be lowered, the time span of the drying process is too long, and the entire process from low temperature setting to medium temperature drying room Time ≥ 56 hours, because the temperature in the drying room is too high
The moisture is not exhausted enough, so the requirements for manual turning of the meatballs are very high, and people are prone to fatigue, heatstroke and other phenomena when continuously operating the meatballs at a high temperature above 40°C
[0007] 3. The drying air supply is uneven, which leads to rework of the process. Due to the design defect of the crawler conveying form, the air duct is ...

Method used

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  • A New Technology for Drying Soft Capsules
  • A New Technology for Drying Soft Capsules

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] 1. Soft capsule finalization: Turn on the rotary dehumidifier unit before setting the shape, adjust the humidity of the rotary dehumidifier to 40%, the temperature to 20°C, and control the temperature and humidity of the room to 45-35%, and the temperature to 18-24°C. The capsules were transferred to a sizing tumbler for 2 hours of sizing and drying.

[0026] 2. The soft capsules are dried in a tumbler: the shaped capsules are transferred to a drying tumbler for drying. The drying time is 7 hours, the temperature is 26-32°C, and the humidity is 35-25%. After the drying in the tumbler cage, it was detected that the moisture content of the capsule shell was controlled at 15.6%.

[0027] 3. Tray drying: After the tumbler drying, transfer to the tray for drying, the drying time is 12 hours, the temperature requirement is 20-26°C, and the humidity requirement is 20-30%. Select the unqualified capsules, and after the drying of the tray, the capsules are detected to be 9.6% (...

Embodiment 2

[0029] 1. Soft capsule finalization: Turn on the rotary dehumidifier unit before finalizing, adjust the humidity of the rotary dehumidifier to 42%, the temperature to 19°C, and control the temperature and humidity of the room to 45-35%, and the temperature to 18-24°C. The capsules were transferred to a sizing tumbler for 3 hours of sizing and drying.

[0030] 2. The soft capsules are dried in a tumbler: the shaped capsules are transferred to a drying tumbler for drying. The drying time is 8 hours, the temperature is 26-32°C, and the humidity is 35-25%. After the tumbler drying, the moisture content of the capsule shell was detected to be controlled at 14.8%.

[0031] 3. Tray drying: After the tumbler drying, transfer to the tray for drying, the drying time is 10 hours, the temperature requirement is 20-26°C, and the humidity requirement is 20-30%. Select the unqualified capsules, and after the drying of the tray, the capsules are detected to be 9.2% (the standard of 8% to 12%...

Embodiment 3

[0033] 1. Soft capsule finalization: Turn on the rotary dehumidifier unit before finalizing, adjust the humidity of the rotary dehumidifier to 39%, the temperature to 21°C, and control the temperature and humidity of the room to 45-35%, and the temperature to 18-24°C. The capsules were transferred to a sizing tumbler for 4 hours of sizing and drying.

[0034] 2. The soft capsules are dried in a tumbler: the shaped capsules are transferred to a drying tumbler for drying. The drying time is 6 hours, the temperature is 26-32°C, and the humidity is 35-25%. After the tumbler drying was finished, it was detected that the capsule shell moisture was controlled at 14.2%.

[0035] 3. Tray drying: After the tumbler drying, transfer to the tray for drying, the drying time is 11 hours, the temperature requirement is 20-26°C, and the humidity requirement is 20-30%. Select the unqualified capsules, and after the drying of the tray, the capsules are detected to be 8.9% (the company accepts p...

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Abstract

The invention discloses a new technology for drying soft capsules, which is composed of soft capsules shaping, drying in a tumbler and tray drying. For air control, the air supply in the drying room adopts a horizontal circulation air supply system. By adjusting the temperature and humidity in the drying room, the practical problems such as capsule adhesion and cracking of soft capsules under the traditional drying technology can be effectively solved, so that the freshly pressed soft capsules can be dried stably, and the quality of the product is also reduced. drying costs.

Description

Technical field: [0001] The invention relates to a new technology for drying soft capsules, which is designed for the pharmaceutical industry and belongs to the field of drying soft capsule medicines. Background technique: [0002] Soft capsules were invented by French pharmacist Mothes in 1883. After embedding oily medicines in capsules, they can be taken as a solid medicine more conveniently. Bad smell, beautiful appearance, easy to carry and use, etc. Among oral drugs in different dosage forms, the bioavailability is best in soft capsules containing solution-like contents. [0003] The soft capsules are prepared by pressing method or dripping method, and the soft capsules all need to be dried after molding. The water contained in the soft capsule wall has a certain influence on the disintegration time of the medicament. Since the main component of the soft capsule shell is gelatin, it consists of more than 85% protein, about 2% minerals and about 13% water and contains ...

Claims

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Application Information

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IPC IPC(8): A61J3/07
Inventor 路祖强
Owner 贵州地道药业有限公司
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