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Fiber fluorescent probe and solution-based fiber fluorescent sensing system model

A technology of fluorescent probes and optical fibers, applied in the field of bioluminescence detection, to achieve the effect of low cost, high precision, and less pain

Inactive Publication Date: 2012-05-09
WUHAN UNIV OF TECH
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Problems solved by technology

[0005] The technical problem to be solved by the present invention is to provide an optical fiber fluorescent probe suitable for detecting the content of trace elements in the solution in view of the above-mentioned prior art, using a standard medical syringe needle with a small volume as the detection probe, which overcomes the problem of trace elements in the past. In the detection method, the measurement concentration is low, the operation is complicated, time-consuming, and it is difficult to reduce the pain of the patient, etc.

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  • Fiber fluorescent probe and solution-based fiber fluorescent sensing system model
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  • Fiber fluorescent probe and solution-based fiber fluorescent sensing system model

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Embodiment Construction

[0016] The optical fiber fluorescent probe suitable for detecting the content of trace elements is characterized in that it includes an excitation optical fiber 11, a receiving optical fiber (12, 13), a capillary 14, a permeable membrane 15 and a sleeve 16, and the excitation optical fiber and two receiving optical fibers are present The font arrangement is placed in the capillary, the permeable membrane is fixed on the end of the capillary, and the capillary is filled with bioluminescent probe solution, the capillary 14 is fixed in the sleeve 16, and the distance between the front end of the cylindrical section of the sleeve and the end of the capillary is 2mm.

[0017] According to the above solution, the center of the section circle of the capillary 14 is the center of the regular triangle formed by connecting the section centers of the exciting optical fiber 11 and the receiving optical fiber ( 12 , 13 ).

[0018] According to the above scheme, the excitation fiber is a lar...

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Abstract

The invention relates to a fiber fluorescent probe suitable for detecting the content of trace elements and a solution-based fiber fluorescent sensing system model, and comprises an excitation fiber, reception fiber, capillary, a selectively permeable membrane and a sleeve, the excitation fiber and two reception fiber are arranged as triangle in the capillary, the selectively permeable membrane is fixed at the end surface of the capillary, the capillary is full of a biological fluorescent probe solution, the capillary is fixed in the sleeve, the distance between the front part of a cylinder segment of the sleeve and the end part of the capillary is 2mm. Compared with the prior art, the invention has the following advantages: 1) the structure is simple, the cost is low; 2) the detection issimple and convenient, and can be widely used for real time detection; 3) the fiber structure arranged as triangle enables effective utilization of space position of the sleeve, can effectively enhance the fluorescence acquisition efficiency, and has high precision; 4) a standard medical syringe needle is taken as the sleeve, so that pain of the patients from the human body trace element detection can be reduced.

Description

technical field [0001] The invention belongs to the technical field of biological fluorescence detection and relates to an optical fiber sensor for detecting trace elements in a solution, in particular to an optical fiber fluorescent probe suitable for detecting trace element content and a solution-based optical fiber fluorescence sensing system model. Background technique [0002] The current detection methods of trace elements mainly include: flame Zeeman atomic absorption spectrometry (FAAS), graphite furnace atomic absorption spectrometry (GFAAS), inductively coupled plasma mass spectrometry (ICP / MS), atomic radiation spectrometry and electrochemical methods. Such as anodic adsorption voltammetry (ASV). Both of these AAS methods have the advantage of high sensitivity, but both require extensive sample pretreatment before analysis can begin. This process is slow, laborious and costly. The separate pretreatment process cannot meet the requirements of continuous and real-...

Claims

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Application Information

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IPC IPC(8): G01N21/64G01N21/01
Inventor 黎敏潘忠华莉
Owner WUHAN UNIV OF TECH
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