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Shenkang oral liquid compound preparation for treating chronic renal failure and preparation method of Shenkang oral liquid compound preparation

A Shenkang oral and compound preparation technology, which is applied in liquid transportation, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problems of high proportion of Astragalus membranaceus, precipitation reaction, and no ratio relationship

Active Publication Date: 2013-12-18
XIAN SHIJISHENGKANG PHARMA IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The original patent 200410039418.X discloses a kind of Shenkang suppository and its preparation method. Its prescription protects the scope of use of traditional Chinese medicine, and there is no specific ratio relationship. Although the case of the prescription is also disclosed in the patent document embodiment, but The proportion of astragalus contained in it is high, astragalus and rhubarb have a precipitation reaction, and astragalus and salvia miltiorrhiza also have a reaction, and the small amount of astragalus in the compatibility of the preparation also affects the efficacy of the medicine, so the ratio of traditional Chinese medicine directly affects the curative effect of the preparation. Precise and Minimal Side Effects Are Crucial

Method used

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  • Shenkang oral liquid compound preparation for treating chronic renal failure and preparation method of Shenkang oral liquid compound preparation
  • Shenkang oral liquid compound preparation for treating chronic renal failure and preparation method of Shenkang oral liquid compound preparation
  • Shenkang oral liquid compound preparation for treating chronic renal failure and preparation method of Shenkang oral liquid compound preparation

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Effect test

Embodiment 1

[0098] The Shenkang oral liquid compound preparation of the present invention is made from the following raw materials: rhubarb 1500g, salvia miltiorrhiza 1500g, astragalus membranaceus 4500g and safflower 1500g.

[0099] After extracting the raw materials rhubarb and salvia according to the proportion of the above formula, first alcohol precipitation, detanning, second alcohol precipitation, water precipitation, third alcohol precipitation, and second water precipitation; astragalus and safflower according to the above formula Proportional extraction, alcohol precipitation again, water precipitation, alcohol precipitation again, water precipitation, concentration, and auxiliary materials are added.

Embodiment 2

[0101] The preparation method of Shenkang oral liquid preparation is as follows: take rhubarb and salvia miltiorrhiza, add 7-12 times the amount of the original medicinal materials for the first time, soak for 30 minutes, boil for 30 minutes, filter, and add water for the second time 7-12 times the original medicinal materials. -12 times the amount, boil for 30 minutes, filter, add water for the third time to 7-12 times the original medicinal material, boil for 30 minutes, filter, combine three water extracts, concentrate to a relative density of 1.18 to 1.25 at 60°C, add 95% ethanol, until the alcohol content of the medicinal solution is 70%, let it stand for 38-60h, take the supernatant and filter until clear, recover the ethanol until the relative density is 1.18-1.25 at 60°C, add 5% gelatin solution, remove tanning, Add 95% ethanol until the alcohol content is 75%, let it stand for 38-60 hours, take the supernatant, filter and clarify, recover the ethanol until the relative...

Embodiment 3

[0103] The preparation method of Shenkang oral liquid preparation is as follows: take rhubarb and salvia miltiorrhiza, add 10 times the amount of the original medicinal materials for the first time, soak for 30 minutes, boil for 30 minutes, filter, and add water for the second time 8 times the amount of the original medicinal materials , boil for 30 minutes, filter, add water for the third time to 7 times the amount of the original medicinal material, boil for 30 minutes, filter, combine three water extracts, concentrate to a relative density of 1.20-1.22 at 60 ° C, add 95% ethanol, until the drug The alcohol content of the solution is 70%, let stand for 48-60h, take the supernatant and filter until clear, recover the ethanol until the relative density is 1.20-1.22 at 60°C, add 5% gelatin solution, remove tanning, add 95% ethanol, until The alcohol content is 75%, stand still for 48-60h, take the supernatant, filter and clarify, recover the ethanol until the relative density is...

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Abstract

The invention relates to a Shenkang oral liquid compound preparation for treating chronic renal failure, which is characterized by being prepared from the following bulk pharmaceutical chemicals: 1500g of rheum officinale, 1500g of roots of red-rooted salvia, 4500g of Astragalus mongholicus and 1500g of red flower. The preparation method comprises the following steps of: after the bulk pharmaceutical chemicals of the rheum officinale and the roots of red-rooted salvia are extracted in the ratio in the formula, carrying out primary ethanol precipitation, removing tan, carrying out secondary ethanol precipitation and water precipitation, carrying out third ethanol precipitation, and carrying out secondary water precipitation; and then, extracting the red flower and the Astragalus mongholicus in the ratio in the formula, carrying out primary ethanol precipitation and water precipitation, carrying out secondary ethanol precipitation and water precipitation, and condensing to obtain the oral liquid compound preparation. The Shenkang oral liquid compound preparation has the advantages of precision in regulating the original ratio, high in content of effective ingredients in the unit volume, few precipitations, small side effect, high acting speed and high bioavailability.

Description

technical field [0001] The invention belongs to a traditional Chinese medicine oral liquid preparation and a preparation method thereof, in particular to a Shenkang oral liquid compound preparation for treating chronic renal failure and a preparation method thereof. Background technique [0002] The original patent 200410039418.X discloses a kind of Shenkang suppository and its preparation method. Its prescription protects the scope of use of traditional Chinese medicine, and there is no specific ratio relationship. Although the case of the prescription is also disclosed in the patent document embodiment, but The proportion of astragalus contained in it is high, astragalus and rhubarb have a precipitation reaction, and astragalus and salvia miltiorrhiza also have a reaction, and the small amount of astragalus in the compatibility of the preparation also affects the efficacy of the medicine, so the ratio of traditional Chinese medicine directly affects the curative effect of t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/08A61K9/10A61K36/708A61P13/12
Inventor 曹凤君吕延英詹芳赵兴王光建王俊平
Owner XIAN SHIJISHENGKANG PHARMA IND
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