Double-fiber tablet and preparation method thereof

A technology of corn cellulose and microcrystalline cellulose, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of dependence, large dosage, and poor drug efficacy, and achieve intestinal stimulation Peristalsis, low production cost, effect of reducing food intake

Inactive Publication Date: 2012-07-04
TIANJIN TIANSHI BIOLOGICAL DEV +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term use of laxatives not only leads to dependence, but also increases the dosage as the time of taking the medicine increases, and the efficacy of the medicine becomes worse and worse.

Method used

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  • Double-fiber tablet and preparation method thereof
  • Double-fiber tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A method for preparing a double-fiber sheet, comprising the steps of:

[0023] (1) Weighing by mass percentage: polydextrose 35%, hawthorn powder 20%, low-substituted hydroxypropyl cellulose 15%, corn cellulose 13%, gelatin 7%, microcrystalline cellulose 8%, magnesium stearate 2%;

[0024] (2) passing through 40 mesh sieve and 60 mesh sieve successively to make the particle diameter of described polydextrose, hawthorn powder, low-substituted hydroxypropyl cellulose, corn cellulose, microcrystalline cellulose, magnesium stearate be 40-60 mesh ,spare;

[0025] (3) add gelatin in boiling water, stir while adding, make the liquid be the gelatin slurry of uniform transparent shape, make the mass concentration of described gelatin in water be 7%, keep warm at 50 ℃;

[0026] (4) Polydextrose, hawthorn powder, low-substituted hydroxypropyl cellulose, corn cellulose, and microcrystalline cellulose processed in step (2) are dropped into a granulator, mixed for 5 minutes, spraye...

Embodiment 2

[0030] A method for preparing a double-fiber sheet, comprising the steps of:

[0031] (1) Weighing by mass percentage: polydextrose 30%, hawthorn powder 25%, low-substituted hydroxypropyl cellulose 20%, corn cellulose 9%, gelatin 5%, microcrystalline cellulose 10%, magnesium stearate 1%;

[0032] (2) passing through 40 mesh sieve and 60 mesh sieve successively to make the particle diameter of described polydextrose, hawthorn powder, low-substituted hydroxypropyl cellulose, corn cellulose, microcrystalline cellulose, magnesium stearate be 40-60 mesh ,spare;

[0033] (3) add gelatin in boiling water, stir while adding, make the liquid be the gelatin slurry of uniform transparent shape, make the mass concentration of described gelatin in water be 6%, keep warm at 45 ℃;

[0034] (4) Put polydextrose, hawthorn powder, low-substituted hydroxypropyl cellulose, corn cellulose, and microcrystalline cellulose processed in step (2) into a granulator, mix for 3 minutes, spray into the g...

Embodiment 3

[0038] A method for preparing a double-fiber sheet, comprising the steps of:

[0039] (1) Weighing by mass percentage: polydextrose 40%, hawthorn powder 18%, low-substituted hydroxypropyl cellulose 10%, corn cellulose 15%, gelatin 10%, microcrystalline cellulose 5%, magnesium stearate 2%;

[0040] (2) passing through 40 mesh sieve and 60 mesh sieve successively to make the particle diameter of described polydextrose, hawthorn powder, low-substituted hydroxypropyl cellulose, corn cellulose, microcrystalline cellulose, magnesium stearate be 40-60 mesh ,spare;

[0041] (3) add gelatin in boiling water, stir while adding, make liquid be the gelatin slurry of uniform transparent shape, make the mass concentration of described gelatin in water be 8%, keep warm at 55 ℃;

[0042] (4) Polydextrose, hawthorn powder, low-substituted hydroxypropyl cellulose, corn cellulose, and microcrystalline cellulose processed in step (2) are dropped into a granulator, mixed for 7 minutes, sprayed i...

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Abstract

The invention discloses a double-fiber tablet and a preparation method thereof. The preparation method of the double-fiber tablet comprises the following steps of: (1) weighing polydextrose, hawthorn powder, low-substituted hydroxypropyl cellulose, corn cellulose, gelatin, microcrystalline cellulose and magnesium stearate; (2) sequentially sieving with a 40-mesh sieve and a 60-mesh sieve to enable the particle sizes of the polydextrose, hawthorn powder, low-substituted hydroxypropyl cellulose, corn cellulose, microcrystalline cellulose and magnesium stearate to be 40-60 meshes for later use; (3) adding the gelatin into boiled water, and insulating; (4) putting the polydextrose, hawthorn powder, low-substituted hydroxypropyl cellulose, corn cellulose and microcrystalline cellulose treated in the step (2) into a granulating machine, mixing, injecting gelatin size, granulating and drying; (5) mixing the magnesium stearate with the particles; and (6) tabletting. Through the double-fiber tablet disclosed by the invention, a layer of protective film can be formed in the small intestine, thereby regulating blood fat, reducing fat deposition, preventing obesity and treating constipation.

Description

technical field [0001] The invention relates to a fiber sheet and a preparation method, in particular to a double fiber sheet and a preparation method. Background technique [0002] Dietary fiber plays an important role in the excretion of the human body and is an indispensable substance to maintain human life. If the defecation cannot be carried out smoothly, it will cause harm to the body. The World Health Organization proposed in the new health standard that "eat fast, digest fast, and excrete fast". If this standard can be met, it means that the human digestive system is functioning normally, otherwise it means that there is a problem with the digestive system. With the continuous improvement of people's living standards, the food eaten is more and more refined, and constipation has become a common disease among the crowd. This disease not only reflects the disorder of the digestive system function, but also the top sign of systemic diseases, such as long-term constipat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61K31/717A61K38/17A61K9/20A61P1/10A61P3/06A61P9/10A61P1/16A61P9/00A61P3/10A61P3/04A61K31/716
Inventor 袁锡贵白洁李金元
Owner TIANJIN TIANSHI BIOLOGICAL DEV
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