Method for preparing medical disinfection couplant

A technology of coupling agent and preparation steps, applied in the field of medical devices, can solve the problems of monotony, easy to produce drug resistance, difficult to adapt to various clinical needs, etc., and achieve the effect of reducing costs, reducing the burden of medical expenses, and low prices

Active Publication Date: 2012-07-18
JIANGSU 139 MEDICAL DEVICES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Now the products officially produced in China are all carbomer gel type, but the products are mainly ordinary type for intact skin, which is too monotonous and difficult to meet various clinical needs, especially intracavitary B-ultrasound, due to direct contact with mucous membrane, Sterilized coup...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A kind of medical sterilizing coupling agent is preferably formulated with the following raw materials in weight percentage:

[0035] Carbomer 980 0.3%;

[0036] Sodium hydroxide 0.12%;

[0037] Glycerin 3%;

[0038] Cetyl pyridinium chloride 1%;

[0039] Purified water balance.

[0040] The cetylpyridinium chloride mentioned above is in a solution state, which is prepared by dissolving anhydrous cetylpyridinium chloride in 95% medical alcohol, stirring and dissolving.

[0041] Concrete preparation steps are:

[0042] (1) Add purified water into the batching tank of the high-speed mixer, stir the water out of the vortex through the high-speed mixer, add the raw material powder of Carbomer 980 to the water vortex, and stir until completely dissolved;

[0043] (2) Add purified water into another stainless steel batching bucket, add sodium hydroxide into the water, and stir until completely dissolved;

[0044] (3) Pour the fully dissolved sodium hydroxide solution in...

Embodiment 2

[0054] A kind of medical sterilizing coupling agent is preferably formulated with the following raw materials in weight percentage:

[0055] Carbomer 980 0.3%;

[0056] Sodium hydroxide 0.12%;

[0057] Glycerin 3%;

[0058] Chlorine dioxide 1%;

[0059] Purified water balance.

[0060] Concrete preparation steps are:

[0061] (1) Add purified water into the batching tank of the high-speed mixer, stir the water out of the vortex through the high-speed mixer, add the raw material powder of Carbomer 980 to the water vortex, and stir until completely dissolved;

[0062] (2) Add purified water into another stainless steel batching bucket, add sodium hydroxide into the water, and stir until completely dissolved;

[0063] (3) Pour the fully dissolved sodium hydroxide solution into the fully dissolved carbomer solution, and stir while pouring in;

[0064] (4) After the two solutions are mixed, keep stirring for 20-30 minutes;

[0065] (5) add glycerin, chlorine dioxide in mixed...

Embodiment 3

[0073] A kind of medical sterilizing coupling agent is preferably formulated with the following raw materials in weight percentage:

[0074] Carbomer 980 0.3%;

[0075] Sodium hydroxide 0.12%;

[0076] Glycerin 3%;

[0077] Triclosan 0.5%;

[0078] Sodium Laureth Sulfate 0.3%;

[0079] Vitamin B5 0.2%;

[0080] Purified water balance.

[0081] Concrete preparation steps are:

[0082] (1) Add purified water into the batching tank of the high-speed mixer, stir the water out of the vortex through the high-speed mixer, add the raw material powder of Carbomer 980 to the water vortex, and stir until completely dissolved;

[0083] (2) Add purified water into another stainless steel batching bucket, add sodium hydroxide into the water, and stir until completely dissolved;

[0084] (3) Pour the fully dissolved sodium hydroxide solution into the fully dissolved carbomer solution, and stir while pouring in;

[0085] (4) After the two solutions are mixed, keep stirring for 20-30 min...

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Abstract

The invention provides a method for preparing medical disinfection couplant. The medical disinfection couplant comprises 0.3% of raw material powder of carbomer 980, 0.12% of sodium hydroxide, 3% of glycerol, 1% of cetyl pyridinium chloride and the balance of purified water; the method is that: the carbomer 980 and the sodium hydroxide are respectively dissolved in the purified water, are stirred and mixed by a high-speed mixer, and the glycerol and the cetyl pyridinium chloride are added into the mixed liquor, mixed, then defoamed, filled and disinfected by cobalt 60. The raw materials which are adopted by the medical disinfection couplant are conventional raw materials, can be obtained from a variety of resources, are stable and low in price; and meanwhile, the method is simple, so scale production can be realized, the cost is lowered, and the medical expenses and load of ultrasonic diagnosis and treat are relieved.

Description

technical field [0001] The invention relates to a preparation method of a medical disinfection coupling agent, in particular to a preparation method of a medical disinfection coupling agent with disinfection function used in ultrasonic detection and treatment of skin and cavity mucous membrane, belonging to the field of medical devices. Background technique [0002] When ultrasound is used clinically for diagnosis and treatment, in order to avoid the interference of gas on the image, a layer of couplant will be applied to the ultrasound probe. In clinical operations, the couplant needs to be in close contact with the skin and the radiating surface of the probe, and it is inevitable to contaminate the clothes. Therefore, in addition to the acoustic properties, the couplant must also meet the requirements of not irritating the skin, not damaging the probe, and not sticking to the clothes. However, the domestic carboxymethyl cellulose type and paraffin oil type preparations use...

Claims

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Application Information

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IPC IPC(8): A61K49/22A61P31/04
Inventor 孙开源
Owner JIANGSU 139 MEDICAL DEVICES
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