Separating agent for optical isomer

Abstract

Disclosed is a novel separating agent for optical isomers, which is composed of a polymer having an optically active moiety. Specifically disclosed is a separating agent for optical isomers, which is composed of a helical polymer that contains, as a monomer, an aromatic isonitrile having an amide group wherein an optically active amino acid is amide-bonded to an aromatic ring and a carrier that supports the helical polymer by being chemically bonded to the helical polymer at an end portion of the helical polymer.

Description

technical field [0001] The present invention relates to a separating agent for optical isomers, and relates to a separating agent for optical isomers containing a polymer having a helical structure. Background technique [0002] Optical isomers can be used as medicines and their raw materials. In such use on a living body, optical isomers are usually only optical isomers of one of the configurations, and high optical purity is required. As a method for producing optical isomers that require such high optical purity, a method is known in which a liquid chromatography, simulated moving bed chromatography, and supercritical fluid chromatography, etc., by using a material packed with Optical isomers with optical resolution (Optical resolution) can be separated from a mixture of optical isomers such as racemates. structure (for example, refer to Patent Document 1). [0003] As the separating agent for optical isomers, a polymer having an optically active site can be used. Suc...

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Problems solved by technology

However, there is no disclosure of a separating agent for optical isomers containing the polyaromatic isocyanide derivative

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