381 results about "Amide bonds" patented technology

The invention relates to the field of preparation of polyurethane damping materials, in particular to a preparation method of a repairable polyurethane damping material based on multiple hydrogen bonds and metal coordination. Compared with a traditional damping material, the damping material has a higher damping temperature range and has a good damping effect at the temperature of-20 DEG C to 60 DEG C. Multiple reversible hydrogen bonds are introduced through diamine containing amido bonds, the material is endowed with self-repairing and high mechanical strength, and damping and self-repairing performance is further enhanced through pyridine nitrogen atom metal coordination. Starting from molecular structure design, multiple hydrogen bonds and metal-ligand coordination bonds constructed on a polyurethane molecular main chain play a role in synergistic enhancement, energy can be effectively dissipated through dissociation and recombination of the multiple hydrogen bonds and fracture and association of the metal coordination bonds, and the energy consumption is reduced. The polyurethane material is endowed with excellent damping performance and self-healing capability by the dual dynamic action.

The invention provides a low-temperature-impact-resistant food packaging material and a preparation method and application thereof.The low-temperature-impact-resistant food packaging material is prepared from, by mass, 100 parts of polylactic acid, 1-10 parts of modified layered double hydroxide and 5-40 parts of hyperbranched polyester; wherein the modified layered double hydroxide is obtained by treating layered double hydroxide with a composite anionic surfactant and then treating the treated layered double hydroxide with an organic cationic compound with a long alkyl chain; the composite anionic surfactant comprises a first anionic surfactant and a second anionic surfactant; wherein the first anionic surfactant comprises sodium dodecyl sulfate; the second anionic surfactant comprises a sulfonate anionic surfactant containing an amido bond and a catechol structure. Through the formula design, the impact toughness of the material at low temperature can be improved while the mechanical property of polylactic acid is maintained, and the material can be suitable for the field of food packaging.

The invention belongs to the technical field of antibacterial peptides, and particularly relates to an LL-37 derived antibacterial peptide and application thereof. According to the invention, 17-29aa of the LL-37 antibacterial peptide is used as a core fragment and is connected with an amino acid sequence shown as SEQ ID NO: 1 or SEQ ID NO: 2 through an amido bond, the antibacterial activity of the obtained antibacterial peptide is obviously higher than that of the LL-37 antibacterial peptide, and the antibacterial peptide shows an obvious bactericidal effect on clinical drug-resistant bacteria such as acinetobacter baumannii, pseudomonas aeruginosa, escherichia coli, staphylococcus aureus, klebsiella pneumoniae and the like; meanwhile, the cytotoxicity and hemolytic activity are weak, drug resistance is not prone to being generated, bacteria can be rapidly killed in vivo through multiple mechanisms, no obvious cytotoxicity exists, the bacterium load in tissue is remarkably reduced, and the lifetime of a bacterium-infected mouse is prolonged.

The invention belongs to the field of biomedical materials, and discloses a hydrogel patch with piezoelectricity, conductivity and high adhesion and a preparation method and application of the hydrogel patch. Polyvinyl alcohol (PVA) and acrylic acid (AA) serve as polymer frameworks of the hydrogel patch; the invention relates to a nano-zinc oxide / poly (3, 4-ethylenedioxythiophene) / poly (styrenesulfonic acid) (PEDOT: PSS) composite conductive adhesive, which comprises nano-zinc oxide (ZnO) as a piezoelectric material, poly (3, 4-ethylenedioxythiophene)-poly (styrenesulfonic acid) (PEDOT: PSS) as a conductive material, and N-hydroxysuccinimide acrylate (NHS-AA) as an adhesive functional monomer. According to the invention, active ester groups in the N-hydroxysuccinimide acrylate are utilized, so that the patch can quickly form covalent amido bonds with amino groups on the surface of a tissue in a dry state, firm adhesion is realized, local nerve repair can be effectively promoted through a piezoelectric effect, a novel ideal material is provided for disease treatment, and the patch has wide application prospects. Wide clinical application prospects are realized in the field of biological medicines.

The invention belongs to the technical field of functional nano materials, and particularly relates to a preparation method of a detachable engine type braking nano motor, a nano drug carrier is jointly composed of HMSN and CAT modified PNA, tetraethyl orthosilicate serves as a silicon source, and solid silicon dioxide balls are synthesized; on the basis, tetraethyl orthosilicate is used as a silicon source, CTAB is used as a pore-forming agent to synthesize mesoporous silica coated solid silica spheres; etching the core silicon dioxide ball through sodium carbonate to obtain a hollow mesoporous silicon dioxide ball; then, amino modification is carried out on the CAT modified PNA2 through 3-aminopropyltrimethoxysilane, PNA1 is connected with HMSN through an amido bond, and a double-chain structure is formed by the CAT modified PNA2 and PNA1 through complementary base pairing. According to the nano motor provided by the invention, the engine CAT of the nano motor can be detached by adding the unwinding chain PNA3, so that in-vivo deceleration and braking are realized.

The invention relates to the technical field of biomedical material modification, in particular to a sulfhydrylation biocompatible polymer derivative, a preparation method thereof, extracellular matrix imitating injectable in-situ cross-linked hydrogel and application thereof. According to the invention, a pre-acylation strategy is firstly carried out on the biocompatible polymer containing both amino and carboxyl, so that a three-dimensional cross-linked byproduct formed by coupling of self amido bonds is avoided, meanwhile, the number of side chain carboxyl for sulfhydrylation modification is increased, and the accurate and adjustable pre-acylation rate can optimize the physical and chemical properties of the derivative; meanwhile, a disulfide bond is used as a protective precursor, active sulfydryl is introduced through amido bond coupling, self-oxidation of the active sulfydryl in the reaction process is avoided, sulfydryl activity is guaranteed, hydrazine-containing reagents are avoided, safety is further improved, virus residues and immunological rejection risks are avoided, universality is high, and the application prospect is wide; and in combination with a high-concentration preparation method, the method has the advantage of large-scale production, and further widens the industrial application potential.

The invention belongs to the technical field of coatings, and discloses a water-based epoxy coating for automobiles and a preparation method thereof.The water-based epoxy coating is prepared by preparing water-based rigid epoxy resin, water-based flexible epoxy resin, a diamine curing agent and a block polymer as components in the water-based epoxy coating and matching the four components with a step-by-step coating process. High-activity amido in the curing agent and rigid resin form a high-density network to endow the top layer with hardness, the curing agent and flexible resin form hardness and softness to improve the toughness of the bottom layer, epoxy groups of the block polymer and low-activity amido in the bottom layer are covalently anchored, carboxyl and the amido in the top layer form amido bonds, firm molecular bridges are constructed, interlayer reinforced connection is achieved, and the bonding strength is improved. The coating has high hardness, high toughness and excellent interlayer adhesive force, and solves the problem of non-uniform performance caused by low crosslinking density and side reaction of the traditional waterborne epoxy coating.

Provided is a composition for forming a laminated separator for a non-aqueous electrolyte secondary battery, the composition being capable of reducing the amount of increase in air permeability of the laminated separator and improving heat resistance. This composition for forming a laminated separator for a non-aqueous electrolyte secondary battery contains a resin having an amide bond, the resin having an amide bond containing a component eluted into N-methyl-2-pyrrolidone, and the amount of the component eluted into N-methyl-2-pyrrolidone is less than the amount of the component eluted into N-methyl-2-pyrrolidone relative to the weight of the entire resin having an amide bond. The content of the component eluted into N-methyl-2-pyrrolidone is greater than 25.0% by weight and 45.0% by weight or less, and the content of the component eluted into N-methyl-2-pyrrolidone is greater than 25.0% by weight and 45.0% by weight or less.

The invention relates to the technical field of medicines, in particular to a preparation method of semeglutide, which comprises the following steps: by optimizing a coupling sequence, firstly connecting a main peptide chain compound 1 with a side chain compound 5 without carboxyl protection, and then performing subsequent coupling with a dipeptide structure compound 6 with high steric hindrance, thereby obtaining the semeglutide. The problem of excessive modification caused by coexistence of a plurality of active sites in a traditional route is effectively avoided, especially for coupling difficulty brought by the structure of a compound 6, the types of a condensation reagent and a side-chain compound 5 are optimized, dipeptide carboxyl of the compound 5 is remarkably activated, amido bonds can be efficiently formed by the compound 5 and a compound 2 under the mild condition, and the compound 6 can be efficiently synthesized. In the path of synthesizing the compound 3 from the compound 1, one-pot operation is realized, and the reaction liquid in each step can be used for the next step without refining, so that the reaction time and the consumption of raw materials are reduced, and the connection efficiency and selectivity of key steps are greatly improved.

The invention belongs to the technical field of organic synthetic chemistry and pesticide science, and particularly relates to an indole-containing amide derivative as well as a preparation method and application thereof, and the indole-containing amide derivative has a structure as shown in a formula I or a formula II, through an active substructure splicing strategy, indole is used as a parent skeleton, amido bonds are ingeniously introduced for structural diversity optimization and modification, active functional groups such as methoxyamine are further introduced, and a series of indole amide derivatives with novel structures are designed and synthesized. Through determination, the screened series of compounds show good antibacterial activity, and a plurality of compounds show excellent prevention and treatment effects on various important crop diseases.

The invention relates to the technical field of air purification materials, and particularly discloses an amino acid grafted modified covalent organic framework composite material as well as a preparation method and application thereof. The composite material comprises a covalent organic framework matrix and amino acid grafted through covalent bonds, the covalent organic framework matrix has a porous crystal structure, and the amino acid is connected with the matrix through an amido bond or a carbon-nitrogen bond. The preparation method comprises the four main steps of covalent organic framework matrix synthesis, matrix activation, amino acid grafting and product purification. The composite material provided by the invention can be used for indoor air purification, formaldehyde removal of automotive trim and formaldehyde adsorption process in industrial waste gas treatment. The material has a high specific surface area and a rich porous structure, combines specific interaction of amino acid functional groups and formaldehyde molecules, and shows excellent formaldehyde adsorption capacity and selective adsorption performance. The preparation method disclosed by the invention is mild in process condition, and controllable adjustment of material performance is realized by accurately controlling grafting parameters.

A wavelength selective absorption filter contains a resin, a coloring agent, and a compound having at least one polar group of a carboxylic acid ester bond, a carboxylic acid amide bond, a sulfonic acid amide bond, a urethane bond, or a sulfonyl bond and a MW≤1,000 where dye includes at least one of dye A having a main absorption wavelength range at a wavelength of 390 to 440 nm and dye D having a main absorption wavelength range at a wavelength of 680 to 780 nm, a 20% value wavelength A with respect to an absorbance maximal value exhibited by a main absorption wavelength is 455 nm or less where dye A is contained, and a 20% value wavelength D with respect to the absorbance maximal value exhibited by the main absorption wavelength is 640 nm or more where dye D is contained, and a display device.

The application provides a kind of load exosome composite hydrogel and preparation method thereof, belong to biomaterial and drug delivery technical field;Its preparation method includes: modified chitosan;Modified hyaluronic acid;Preparation of biphasic calcium phosphate nanoparticles;Preparation of composite hydrogel.The application is through nucleophilic ring-opening reaction of 1,2-epoxy butane and the hydroxyl group of chitosan, form hydroxybutyl ether bond, give hydroxybutyl chitosan temperature sensitive characteristics, then, again, after activation 3,4-dihydroxyphenylalanine is condensed with hydroxybutyl chitosan, form amide bond, to graft 3,4-dihydroxyphenylalanine on hydroxybutyl chitosan, after modification of chitosan, 3,4-dihydroxyphenylalanine can form strong adhesion interface with cartilage, synovial membrane and other tissues through hydrogen bond, pi-pi stacking and metal coordination, thereby effectively prolonging the residence time of hydrogel in joint.

The application discloses a kind of based on machine learning prediction amide bond molecular synthesis conversion rate method, belong to chemical technical field.The application is based on high-throughput experiment collection reaction conversion rate data, establishes data set, and utilizes quantum chemistry calculation means to extract the feature descriptor of reaction related molecule, and the model after training finds that random forest model only needs a small amount of data to reach good prediction accuracy.Through the prediction of unknown aromatic amine molecular conversion rate in amidation reaction, it is found that a small amount of relevant reaction data can be added in the training set of random forest model to significantly improve the prediction performance of unfamiliar data.This has important guiding significance for exploring the synthesis of amide bond and the future application of machine learning to the field of chemical synthesis.

The invention relates to injectable cross-linked collagen gel and a preparation method thereof. Two crosslinking strategies of self-crosslinking and crosslinking agent crosslinking are fused together for the first time, and two types of amido bonds, namely amido bonds of a collagen-collagen structure (A) and amido bonds of a collagen-fatty amine-collagen structure (B), are respectively constructed through two crosslinking paths, namely catalysis of collagen polypeptide self-crosslinking and catalysis of fatty amine crosslinking, so that a hard / soft dual crosslinking network is obtained. The relative proportion of the structure A and the structure B in the final product is adjusted through a proper cross-linking process, so that the strength and the stability of the final product are adjusted and controlled, and the use requirements of different injection parts can be met.

The invention discloses a high-epoxy-adhesion long-carbon-chain nylon composition as well as a preparation method and application thereof. The high-epoxy-adhesion long-carbon-chain nylon composition is prepared from the following components in parts by weight: 79-94 parts of long-carbon-chain nylon, 5-20 parts of a toughening agent, 0.2-2 parts of an antioxidant, 0.1-0.5 part of a synergistic stabilizer, 0-1 part of a light stabilizer and 0-2 parts of color master batch, according to the invention, long carbon chain nylon is compounded with the active group grafted polyolefin elastomer flexibilizer to synergistically improve the toughness of the material and the adhesive force to a prime coat material containing an epoxy component, the active group grafted flexibilizer greatly improves the toughness of a nylon matrix, and the functional group of the active group grafted flexibilizer is used as a chemical anchor point; firm covalent bond combination is formed with the epoxy prime coat, so that high adhesion and high impact strength which are difficult to consider by a traditional material are realized; the catalytic degradation risk of metal ions on amido bonds is reduced through the synergistic stabilizer, long-term stability of the performance of the composition is guaranteed, and the application requirement of coating resin on the surface of the Bundy tube is met.

The application discloses a kind of high toughness biomass-based composite film for liquid packaging and its preparation method and application, belong to biomass-based packaging material technical field.The composite film is ABA three-layer co-extrusion structure;A layer is composed of modified PLA, PBAT and lignin-containing cellulose nanofiber;B layer is composed of oligosaccharide modified polyester;A layer master batch and B layer material are prepared respectively, and three-layer co-extrusion molding is obtained.The application uses amide bond to covalently fix oligosaccharide on polyester main chain, solves the problems of existing technology, such as easy migration of antibacterial agent, weak interlayer bonding force and insufficient comprehensive performance;Through multivariate blending, the synergistic improvement of mechanical property and barrier property is realized by using multiple intermolecular forces;ABA three-layer co-extrusion structure is used, and interface firm combination is realized by means of interlayer molecular diffusion and hydrogen bond network.The obtained composite film has high toughness, excellent barrier property and antibacterial property, and is suitable for milk, fruit juice and other liquid food packaging.

A separator for a non-aqueous secondary battery contains: a porous layer that is provided on only one side of the porous substrate, and that contains a resin having at least one bonding group selected from an amide bond, an imide bond, and a sulfonyl bond, in which, in the porous substrate, an absolute value of a difference between a temperature of an endothermic peak observed at 120° C. to 145° C., in a temperature raising process 1, and a temperature of an endothermic peak observed at 120° C. to 145° C., in a temperature raising process 2, is 1.50° C. or higher in DSC measurement when the temperature raising process 1 of continuously raising the temperature from 30° C. to 200° C. at a temperature change rate of 5° C. / min in a nitrogen atmosphere, and the temperature raising process 2 of lowering the temperature from 200° C. to 30° C. and raising the temperature from 30° C. to 200° C., are performed.

The invention belongs to the technical field of medical dressings, and provides a hydrocolloid acne patch and a preparation method thereof. According to the invention, beta-cyclodextrin functionalized gelatin and adamantane functionalized hyaluronic acid are subjected to inclusion interaction to form a reversible cross-linked network, and hydroxypropyl trimethyl ammonium chloride chitosan and sodium carboxymethyl cellulose are subjected to electrostatic interaction to form a polyelectrolyte cross-linked network; the genipin is combined with a primary amine group amido bond to form a triple cross-linked network structure design of a covalent cross-linked network, and antibacterial components such as a gamma-cyclodextrin-salicylic acid inclusion compound are loaded, so that the excellent properties that the self-healing recovery rate is 90-95%, the water vapor transmission rate is 500-900g. M <-2 >. 24h <-1 >, and the peel strength is greater than or equal to 1.0 N / 25mm are realized; the technical problem that an existing hydrocolloid acne patch is insufficient in antibacterial persistence and self-healing and repairing capacity is solved, and wide application value is achieved.

The invention belongs to the field of functional textile materials and filtering materials, and provides a multi-effect functional non-woven fabric. According to the invention, a collaborative design of a composite non-woven structure and an immobilized functional layer is adopted, and the composite non-woven structure is composed of a spun-bonded layer containing polyamide 6 and a melt-blown layer containing maleic anhydride grafted polyamide 6; the immobilized functional layer comprises quaternized chitosan-sodium tripolyphosphate ionic cross-linked nanoparticles and forms amido bonds through ring-opening reaction of anhydride groups and amino groups, and the amido bonds are firmly fixed on the surface of the composite non-woven structure; multiple properties such as low-pressure-drop high-flux filtration, efficient particulate matter trapping, high-positive-charge antibacterial and hydrophilic multi-effect synergy, long-acting stable fixation of a functional layer in a humid and hot environment and the like are realized, and the technical problem that performance synergy, interface stability and process compatibility of an existing filtration protection material are difficult to consider is solved; wide application values are realized in the fields of air filtration, personal protection, medical treatment and public health and the like.

The application provides a polyamide-PVA-polyamine COF composite film and a preparation method thereof, and belongs to the technical field of membrane separation. The polyamide-PVA-polyamine COF composite film provided by the application comprises a polyamide COF film and a polyamine COF film, and the polyamide COF film is bonded to the polyamine COF film through PVA. The main body of the polyamide-PVA-polyamine COF composite film provided by the application is composed of a crystalline porous polymer-covalent organic framework (COF) with an ordered pore structure, the units are connected to each other through amide bonds, and the internal rich and highly ordered pores make the COF composite film exhibit high separation precision.

The present application provides a cross-linked complex, a preparation method therefor, and a use thereof in sequencing. The cross-linked complex comprises: a protein and a semiconductor chip, the protein being connected to the semiconductor chip by means of a group A, the group A having a structure as shown in formula (A), or a stereoisomer, a tautomer or a salt of the structure shown in formula (A), the protein being connected to the group A by means of an amide bond, and the semiconductor chip being connected to the group A by means of an amide bond, W being -(CH2)n1- or -(CH2CH2O)n2CH2CH2-, and n1 and n2 each being a positive integer.

Provided is an electrode-forming composition which is suppressed in thickening and gelling by a simple method, has improved storage stability, and is capable of increasing the concentration of solid content, said electrode-forming composition containing a heterocyclic ring-containing compound, a positive electrode active material, a binder, and a solvent, the heterocyclic ring-containing compound is a heterocyclic ring having a five-membered ring or a six-membered ring, and the heterocyclic ring contains two or more bonds selected from the group consisting of an amide bond and a thioether bond.

The cellulose acylate film of the present application contains a hydrogen-bonding compound satisfying the following (A) requirement, and satisfies the following (B) optical values. (A): having a fluorene skeleton, and having a group containing an amide bond at the 9-position of the fluorene skeleton, or having a carbazole skeleton, and having a group containing an amide bond at the 9-position of the carbazole skeleton. (B): a retardation value Ro in the range of 40 to 70 nm, a retardation value Rt in the range of 100 to 220 nm, and a ratio of the retardation values Rt / Ro in the range of 2.0 to 5.5.

This application relates to bioabsorbable cationic steroidal antimicrobial (CSA) compounds or salts thereof having a structure of formula I, II or III: formula (I), formula (II) or formula (III), wherein R1-R 18 At least one of them (e.g., R) 18 This includes monoglycerides or diglycerides of fatty acids linked by ester bonds, and R1-R 18 At least one of them (e.g., R3, R7, and R) 12 ) is an amino acid linked to the steroid backbone via an ester bond or an amide bond, wherein: R 18 It has the following structure: -R 19 -(C=O)-O-C-CR 20 -CR 21 , where R 19 The radical is omitted or selected from alkyl, alkenyl, ynyl, and aryl, and R 20 and R 21 Independently selected from hydroxyl, alkylcarboxyl, and aminoalkylcarboxyl groups, provided that R 20 and R 21 At least one of them is an alkyl carboxyl group, R3, R7 and R 12 It has the following structure: R 24 R 23 N-R 22 -(C=O)-X-, where R 22 It is a substituted or unsubstituted alkyl group, X is oxygen or nitrogen, and R is... 23 and R 24 It is independently hydrogen, alkyl, alkenyl, alkynyl, or aryl. (I)(II)(III)

The invention relates to 200 light, thin and wear-resistant underpants fabric, and belongs to the technical field of fabric. A self-made antibacterial chain extender participates in preparation to obtain modified spandex filaments, and then the modified spandex filaments and cotton fibers are made into the underpants fabric; the quaternary ammonium salt of the antibacterial chain extender can be combined with bacterial cell membranes and interfere cell metabolism, so that efficient bacteriostasis is realized; the flexible long-chain alkyl group has a plasticizing effect, the elasticity loss of the fabric after liquid ammonia finishing is relieved, an amido bond and a cotton fiber hydroxyl group form a hydrogen bond, the interface bonding is enhanced, the layering of a spandex filament and a cotton fiber is avoided, a polycyclic aromatic fused ring and the amido bond form a conjugated system, an intermolecular strong hydrogen bond is matched, the high-temperature stability of the spandex is improved, and the methoxy group can consume chlorine; a conjugated system stabilizes nitrogen-hydrogen bonds, condensed ring steric hindrance hinders chlorine attack, chlorine resistance of the fabric is enhanced, underpants are not prone to loosening and deformation after being worn for a long time, and elasticity and wrapping feeling are kept for a long time.

The application discloses a kind of photoresponsive self-repair antibacterial nylon materials and preparation method thereof.The material is modified nylon 6 polymer, aromatic Schiff base dynamic imine bond generated by condensation reaction of carboxyl benzaldehyde and p-phenylenediamine is embedded in its molecular main chain, which gives the material the ability of light-triggered self-repair without external heat source, and unexpectedly improves the mechanical properties and thermal stability of the material, the molecular chain end is bonded with antibacterial organic acid through amide bond, and the antibacterial organic acid is 2-methyl-4-(trifluoromethyl) thiazole-5-carboxylic acid.The preparation method adopts one-pot two-stage polymerization, after pressure opening ring prepolymerization, pressure relief vacuum is carried out to carry out deep condensation and end-capping, and the product is obtained by extrusion granulation and drying.The material can realize room temperature self-repair under natural light, and the antibacterial component is non-dissolution fixed.The application process is simple, the performance is adjustable, and can be used in the field of intelligent packaging, repairable antibacterial coating and biomedical materials.

The present invention provides a cyclic peptide compound optionally linked to a nucleic acid, the cyclic peptide compound having a cyclic moiety wherein: (1) the cyclic moiety is composed of 13 or 14 amino acid residues; (2) among the amino acid residues constituting the cyclic moiety, the number of N-substituted amino acid residues is 7 or more, the number of amino acid residues in a single side chain is 3 or fewer, and the number of native amino acid residues is 4 or fewer; and (3) the ClogP / total amide bond (ClogP / total AB) is 1.0 to 1.8.

The invention discloses a UIO66-NH2 (at) GE-TiO2 composite photo-anode based on interface amido bond modification as well as a preparation method and application of the UIO66-NH2 (at) GE-TiO2 composite photo-anode. The preparation method comprises the following steps: firstly, enabling a titanium source precursor and carboxyl functionalized graphene to grow a GE-TiO2 photo-anode on a conductive substrate through a hydrothermal method; secondly, growing a UIO66-NH2 layer on the surface of the GE-TiO2 in situ through a secondary hydrothermal method to form a primary composite structure; and finally, carrying out condensation reaction on amino in UIO66-NH2 and carboxyl on the surface of graphene in GE-TiO2 by utilizing a condensation reagent (EDCI / HOBt) to form covalent amido bond bridging, thereby obtaining the final composite photo-anode. Strong coupling between UIO66-NH2 and GE-TiO2 is achieved by constructing a covalent amido bond interface, the amido bond serves as an efficient directional carrier transmission channel, interface charge recombination is remarkably inhibited, and therefore the photoelectrochemical water decomposition performance of the photo-anode is greatly improved. The material has a wide application prospect in the field of green hydrogen production.

This invention provides a silicon-based anode slurry based on amide-bonded polyimide and its application. The silicon-based anode slurry includes an anode active material and a binder material. The anode active material includes a silicon-containing active material, and the binder material includes polyimide and / or its precursor, wherein the precursor is polyamic acid. The polyamic acid is obtained by polycondensation of a diamine monomer and a dianhydride monomer. The polyimide is obtained by imidization of the polyamic acid. The diamine monomer includes an amide-bonded diamine monomer, and the dianhydride monomer includes an aromatic tetracarboxylic acid dianhydride monomer. This invention introduces an amide-bonded structure into the polyimide backbone to construct a functionalized polyimide binder that combines multiple hydrogen bonding effects with moderate electrolyte compatibility, thereby enhancing the interfacial adhesion between the binder and the silicon active material and inhibiting its swelling in the electrolyte.