Biologically active food additive for the prophylaxis of osteoporosis diseases

A biologically active and food supplement technology, applied in food preparation, food science, food ingredients, etc., can solve problems such as entry into other organs and systems, negative effects on the human body, and kidney dysfunction, so as to prevent osteoporosis, Ensure effective absorption

Inactive Publication Date: 2012-10-31
OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOSTJU PARAFARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 1) Unfortunately, all known preparations only directly increase the intake of calcium in the body, rather than eliminating the cause of calcium depletion from the bones
[0005] 2) After taking calcium preparations, calcium may not only enter the bones, but may also enter other organs and systems, especially calcified stones in the kidneys, resulting in renal dysfunction
[0013] The reason is that testosterone preparations are stimulant drugs and have many negative effects on the human body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Provide 17 kg of calcium gluconate powder and mix it with 83 kg of drone freeze-dried. The mixture is stirred until homogeneous, and the resulting product is encapsulated.

Embodiment 2

[0042] Provide 90 kg of calcium carbonate and mix it with 10 kg of drone freeze-dried. Stir the mixture until homogeneous, and then press into tablets.

[0043] In order to prevent osteoporosis, one capsule of biologically active food supplement was administered three times a day for a month, separated from meals. A one-month stop period should be provided. The blood calcium level will not decrease during this period. In other words, the calcium content will remain at a normal level.

[0044] The above technical effects are confirmed by the following examples.

example 1

[0046] Human subject, female, born in 1959. The DXT-200 optical density instrument obtained from Osteometr was used to measure the mineral bone density of the distal forearm as T-1.4. Osteopenia was diagnosed and 1 gram of calcium gluconate was administered 3 times a day. A 6-month preventive medication course was carried out. During the review period six months later, the decreased bone density was measured to be T-1.6. That is, the mineral bone density (MBD) is reduced. One month after the administration was stopped, the blood calcium level was lower than normal.

[0047] reference:

[0048] Normal MBD-Tcriterium value with a standard deviation of +1 to -1 from the peak bone mass

[0049] Primary osteopenia-MBD is -1 to -1.5

[0050] Secondary osteopenia-MBD from -1.5 to -2

[0051] Tertiary osteopenia-MBD from -2 to -2.5

[0052] First-degree osteoporosis-MBD is -2.5 and below, almost no fracture

[0053] Secondary osteoporosis-MBD of -2.5 and below, with fewer osteoporotic fract...

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PUM

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Abstract

The invention relates to biologically active food additives and is intended for prophylactic activity for conditions associated with osteoporosis. The technical result consists in producing a biologically active food additive which maintains a normal level of testosterone in the body and provides for effective calcium uptake by the body and the retention of this calcium in the bone tissue for a long period of time, which, in turn, promotes the prophylaxis of osteoporosis diseases.

Description

Technical field [0001] The present invention relates to biologically active food supplements, and is expected to be used for preventive effects against osteoporosis-related states. Background technique [0002] Osteoporosis (decreased calcium content in bone structure) is common knowledge. In order to solve this problem, usually based on calcium carbonate, calcium citrate, calcium gluconate, calcium aspartate, calcium ascorbate, calcium amino acid chelate, calcium fumarate, calcium succinate, calcium phosphate, calcium citrate and Calcium preparations of other compounds. It is known that calcium preparations together with vitamin D will be better absorbed. Therefore, many drugs are known, for example, calcium gluconate tablets (registration No. 000140 / 02-2001MZRF), Nycomed's D3 calcium tablets (registration No. 013478 / 01-2001, etc.). [0003] The prior art formulation has the following disadvantages: [0004] 1) Unfortunately, all known preparations only directly increase the int...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/30A23L1/304A23L1/076A23L21/20A23L33/00A61K35/63
CPCA61K33/00A23V2002/00A61K35/642A61K31/198A61K31/194A61K31/191A23L1/304A23L1/30A61K31/075A23V2200/306A23V2250/1578A23L33/10A23L33/16A61K35/63A61P19/10A61K2300/00
Inventor 狄米奇吉纳德维奇·伊利斯拉托夫
Owner OBSHCHESTVO S OGRANICHENNOJ OTVETSTVENNOSTJU PARAFARM
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