PPI (Point-Point Interaction) network clustering method based on artificial swarm reproduction mechanism
A technology of PPI network and artificial bee colony, applied in the field of bioinformatics computing
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[0150] In this embodiment, the PPI data set collected from the MIPS database is used as a simulation data set, which provides information about open reading frames, RNA genes, and other genetic factors. The experimental platform is Windows XP operating system, Intel Core 2 dual-core 2.0GHz processor, 2GB physical memory, and Matlab 7.7 software is used to implement the CM_MBABC method of the present invention. Specific steps are as follows:
[0151] (1) Convert the PPI network into an undirected weighted graph;
[0152] (2) Set the parameters: let count and maxcount respectively represent the current iteration number of the control outer loop and the maximum iteration number corresponding to the outer loop, let maxcount=100; iter, maxiter respectively represent the current iteration number of the control inner loop and the corresponding inner loop The maximum number of iterations, let maxiter=150; E and S denote the energy and speed of the queen bee’s marital flight respectively, ...
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