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Vitiligo covering composition and preparation method thereof

A technology of vitiligo and composition, applied in the field of vitiligo covering composition and its preparation, can solve problems such as difficult coloring, allergies, light, heat, humidity, air and alkaline pH value sensitivity

Active Publication Date: 2013-07-10
北京三和丽生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Second, the instability of dihydroxyacetone in aqueous solutions restricts the development of dihydroxyacetone-containing compositions, and dihydroxyacetone is sensitive to light, heat, humidity, air, and alkaline pH
As time goes by, the color of dihydroxyacetone products will gradually deepen, accompanied by a strange smell, making it difficult for users to accept, and the effect of covering vitiligo is not particularly perfect, there is irreparable color difference, and it is difficult to Coloring, the coloring effect is unstable, and many people have allergies
All of the above have seriously limited the development and application of this type of covering agent.

Method used

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  • Vitiligo covering composition and preparation method thereof
  • Vitiligo covering composition and preparation method thereof
  • Vitiligo covering composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] 1) Weigh 60 parts of cyanobacteria, 40 parts of green algae, 25 parts of brown algae, 15 parts of red algae, 12 parts of fucus, and 5 parts of sugar beet, and set aside;

[0024] 2) Add the raw materials of step 1) into the extraction tank, add water 10 times the weight of the raw materials, adjust the pH value to 3, soak for 24 hours, boil for 5 hours, cool naturally, then perform ultrasonic extraction for 6 hours and filter, concentrate and extract Liquor obtains crude extract A;

[0025] 3) Using supercritical CO2 fluid extraction technology to further extract the crude extract A, wherein the extraction temperature is 35°C and the pressure is 8MP to obtain the fine extract B;

[0026] 4) Dissolve the fine extract B in 95% ethanol under stirring at 35°C. When the crude extract B is completely dissolved, quickly move it to an ice-water bath to cool down, and white powder is precipitated, which is the deep-sea seaweed extraction of the present invention. things.

Embodiment 2

[0028] 1) Weigh 65 parts of cyanobacteria, 48 parts of green algae, 26 parts of brown algae, 18 parts of red algae, 14 parts of fucus, and 7 parts of sugar beet respectively according to the formula, and set aside;

[0029] 2) Add the raw materials of step 1) into the extraction tank, add water 10 times the weight of the raw materials, adjust the pH value to 3, soak for 24 hours, boil for 5 hours, cool naturally, then conduct ultrasonic extraction for 8 hours and filter, concentrate and extract Liquor obtains crude extract A;

[0030] 3) Using supercritical CO2 fluid extraction technology to further extract the crude extract A, wherein the extraction temperature is 40°C and the pressure is 8MP to obtain the fine extract B;

[0031] 4) Dissolve the fine extract B in 95% ethanol under stirring at 36°C. When the crude extract B is completely dissolved, quickly move to an ice-water bath to cool down, and white powder is precipitated, which is the deep-sea seaweed extraction of the...

Embodiment 3

[0033] 1) Weigh 70 parts of cyanobacteria, 55 parts of green algae, 30 parts of brown algae, 25 parts of red algae, 18 parts of fucus and 9 parts of sugar beets respectively according to the formula, and set aside;

[0034] 2) Add the raw materials of step 1) into the extraction tank, add water 14 times the weight of the raw materials, adjust the pH value to 4, soak for 24 hours, boil for 7 hours, cool naturally, then perform ultrasonic extraction for 10 hours and filter, concentrate and extract Liquor obtains crude extract A;

[0035] 3) Using supercritical CO2 fluid extraction technology to further extract the crude extract A, wherein the extraction temperature is 45°C and the pressure is 25MP to obtain the fine extract B;

[0036] 4) Dissolve the fine extract B in 95% ethanol under stirring at 38°C. When the crude extract B is completely dissolved, quickly move it to an ice-water bath to cool down, and white powder is precipitated, which is the deep-sea seaweed extraction o...

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Abstract

A deep-sea seaweed extract having a vitiligo covering effect is characterized in that: raw materials of the extract include 60-80 parts of blue algae, 40-60 parts of green algae, 25-40 parts of brown algae, 15-30 parts of red algae, 12-26 parts of fucus, and 5-15 parts of beets; and the preparation method includes extracting a crude extract A by ultrasonic extraction, then preparing a fine extract B by using a supercritical CO2 fluid extraction method, and obtaining white powder of the deep-sea algae extract after recrystallization. Daubing the deep-sea seaweed extract of the invention by external use, a color similar to the color of skin can be quickly formed on white spots to cover the white spots, the skin is colored safely, and the effect is naturally beautiful, very uniform and lasting. Under normal circumstances, the coloring can last for 5-15 days.

Description

technical field [0001] The invention belongs to the field of cosmetics for covering vitiligo, and specifically relates to a composition for covering vitiligo and a preparation method thereof. The composition for covering vitiligo has the function of covering white spots and beautifying the skin. Compared with the existing covering agents, the composition has fast coloring and long-lasting coloring , and the effect is very natural. Background technique [0002] Vitiligo is a common multiple-occurrence pigmented skin disease. The disease is characterized by localized or generalized depigmentation to form leukoplakia. It is an acquired localized or generalized skin depigmentation disease. It is a common skin disease that affects beauty. It is easy to diagnose but difficult to treat. Vitiligo is the acquired localized white patches caused by depigmentation of the skin, which makes the local skin appear white-like. In medicine, this lesion is usually called depigmentation. Viti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/97A61Q1/08
Inventor 胡发刚南晓丽
Owner 北京三和丽生物科技有限公司
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