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Application of effective parts of salvianolic acid in the preparation of preparations for treating skin diseases

A technology of salvianolic acid and dermatological preparations, which is applied in the application field of the effective parts of salvianolic acid in the preparation of preparations for treating dermatological diseases, and can solve the problems of easy drug resistance, large side effects and high price of antibiotics, etc. problems, to achieve the effect of easy mass production, no irritation, simple and convenient use

Inactive Publication Date: 2014-10-08
邵文远 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hormone drugs have large side effects and are prone to relapse after cure; antibiotics are prone to drug resistance; laser and other physical methods are generally expensive

Method used

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  • Application of effective parts of salvianolic acid in the preparation of preparations for treating skin diseases
  • Application of effective parts of salvianolic acid in the preparation of preparations for treating skin diseases
  • Application of effective parts of salvianolic acid in the preparation of preparations for treating skin diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Prepare solutions.

[0026] Use 75 grams of solid powder of the effective part of Salvia miltiorrhiza (prepared in Example 6), mix with 50 milliliters of distilled water, then dilute to 100 milliliters with water to make an aqueous solution, centrifuge to remove the precipitate, and the supernatant can be used as a solution for treating skin diseases agent. Apply it on the surface of skin warts and herpes, three times a day, each dose is 0.4 and 0.8 ml, respectively, after 35 days and 25 days of treatment, their skin warts and herpes almost disappeared ( Figure 1-2 ).

Embodiment 2

[0028] Prepare solutions.

[0029] Use 75 grams of salvianolic acid effective part powder (prepared in Example 6), mix with 50 milliliters of 20% ethanol water solution, then dilute to 100 milliliters with 20% ethanol water solution to make ethanol water solution, centrifuge to remove the precipitate, and the supernatant It can be used as a solution. Apply it on the acne-prone face, apply it three times a day, 2.5ml each time, after 17 days of continuous use, the acne is almost gone ( image 3 ).

Embodiment 3

[0031] Preparation of a solution for the treatment of skin burns.

[0032] Use 75 grams of salvianolic acid effective part powder (prepared in Example 7), mix with 50 milliliters of distilled water, then dilute with water to 100 milliliters to make an aqueous solution, centrifuge to remove the precipitate, the supernatant can be used as a solution, and smear On the surface of the burn wound, a thin film of the effective part of salvianolic acid will be formed, which can isolate the invasion of new bacteria and viruses, and kill the infected bacteria and viruses at the same time. Aggregation, and inhibition of thrombus formation, thereby promoting wound healing. Apply three times a day, 0.8 ml each time, after 20 days of treatment, the burn wound healed ( Figure 4 ).

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Abstract

The invention provides application of an effective site of salvianolic acids to preparation of preparations for treating skin diseases in vitro. The preparations are solution agents, ointment or cream which is prepared from the effective site, which serves as an active ingredient, of the salvianolic acids and pharmaceutic adjuvants; and the content of the effective site of the salvianolic acids in the preparations is 10 to 75 percent. According to different skin diseases, the preparations can be used for treating viral skin diseases such as wart or herpes, bacterial skin diseases such as inflammations and tinea, dermatoma or burn wounds, so that the skin diseases are cured or improved obviously. The preparations are clear in active ingredients, high in content, high in efficiency, safe, non-toxic, convenient to use, low in cost and easy to produce on a large scale, are suitable for various people and have high application value, and sequelae are avoided.

Description

technical field [0001] The invention relates to traditional Chinese medicines, in particular to the application of effective parts of salvianolic acid in the preparation of preparations for treating skin diseases. Background technique [0002] Dermatosis is the common disease that affects people's health and physical appearance, frequently-occurring disease, easily recurring disease. At present, when more than 2000 kinds of skin diseases are treated externally, most of them are treated with hormone drugs or antibiotic drugs, or with physical methods such as laser. Hormonal drugs have large side effects and are prone to relapse after being cured; antibiotics are prone to drug resistance; physical methods such as lasers are generally expensive. There are also some skin diseases, which cannot be cured for a long time, affect people's physical and mental health and appearance for a long time, and some even lead to canceration. Therefore, finding efficient, safe, nontoxic, chea...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/537A61K31/343A61P17/00A61P17/02A61P31/04A61P31/12A61P35/00
Inventor 邵文远姜雪成邵明川
Owner 邵文远
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