Swallowable drug delivery device and method of drug delivery

A technology for preparations and therapeutic agents, applied in the field of swallowable drug delivery devices, can solve problems such as infection risks
CN102905753BActive Publication Date: 2016-06-29RANI THERAPEUTICS
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
RANI THERAPEUTICS
Publication Date
2016-06-29

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Abstract

Embodiments of the invention provide swallowable devices, formulations and methods for the delivery of pharmaceutical and other therapeutic agents within the gastrointestinal tract. Some embodiments provide swallowable devices, such as capsules, for delivering agents into the intestinal wall or other lumens of the gastrointestinal tract. The device includes a capsule sized to be swallowed and passed through the intestinal tract. The capsule may include at least one catheter, one or more tissue penetrating members located in the catheter, a delivery member, an actuation mechanism, and a release element. The release element degrades upon exposure to various conditions in the gut to release and actuate the actuation mechanism. Embodiments of the invention are particularly useful for the delivery of pharmaceutical agents that are poorly absorbed, poorly tolerated, and / or degrade in the gastrointestinal tract.
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Description

[0001] Cross References to Related Applications

[0002] This application claims the benefit of priority to the following U.S. applications: U.S. Patent Application Serial No. 61 / 339,941, filed March 10, 2010 (Attorney Docket No. 028205-000300US), entitled "Swallowable Drug Delivery Device and Methods of Delivery"; 61 / 284,766, filed December 24, 2009 (Attorney Docket No. 028205-000200US), titled "Swallowable Drug Delivery Device and Methods of Drug Delivery"; 61 / 340,331, filed March 15, 2010 (Attorney Docket No. 028205-000400US ), titled "Swallowable Drug Delivery Device and Methods of Delivery"; and 61 / 395,304, filed May 10, 2010 (Attorney Case Docket No. 028205-000500US), titled "Swallowable Drug Delivery Device and Methods of Delivery," all of which are incorporated by reference in their entirety for all purposes here. This application is also related to U.S. Application Serial No.: _________________, filed December 23, 2010 (Attorney Case Docket No. 028205-000510US), entit...

Claims

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