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Film coating medicine and preparation method thereof

A film coating agent and plasticizer technology, used in pharmaceutical formulations, drug delivery and other directions, can solve the problems of rough product surface, difficult cost control, and non-smoothness.

Active Publication Date: 2014-12-10
GUANGXI JIAJIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The problem that the present invention solves is to provide a kind of film coating agent and preparation method thereof, and it can solve the problem that existing coating agent is dissolved into coating liquid and viscosity is too high or too low, thereby causes the product surface that wraps out to be rough, not easy Slick, unmanageable cost issues

Method used

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  • Film coating medicine and preparation method thereof
  • Film coating medicine and preparation method thereof
  • Film coating medicine and preparation method thereof

Examples

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Embodiment 4

[0035] Example 4 By adjusting the ratio of polyethylene glycol and talcum powder, the disintegration time of the coating layer of the coating can be controlled. Due to their unique properties, polyethylene glycol and povidone can use organic solutions (usually ethanol solutions) as solvents to make coating solutions. All components in this formula can use ethanol as solvents. For products that are sensitive to heat and humidity This coating powder is also applicable.

[0036] Tablet cores with complex ingredients are mostly dark in appearance and color, and the consumer acceptance is low. However, the change in appearance of the present invention is also obvious while improving the taste of the product through coating. The results of Example 5 and Example 6 The purpose of the coating agent is to improve the taste and appearance of the tablet. After coating, it can cover up the bad smell and meet the color requirements of the Chinese patent medicine tablet core.

[0037] 2. Pr...

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Abstract

The invention discloses a film coating medicine and a preparation method thereof and relates to the technical field of film coating for tablets. The active ingredients of the film coating medicine are prepared from the following raw materials in percentage by weight: 45%-55% of hydroxyl propyl methyl cellulose E5 and hydroxyl propyl methyl cellulose E15, 5%-10% of light screen agent, 7%-15% of antisticking agent, 3%-5% of bonding agent, 20%-25% of plasticizer and 5%-10% of coloring agent. Compared with the prior art, the produced product has smooth surface and good moisture resistance, and the production cost can be effectively lowered.

Description

technical field [0001] The invention relates to the technical field of film coating for tablets, in particular to a film coating agent and a preparation method thereof. Background technique [0002] At present, due to the complex taste of plain tablets, poor taste and low consumer acceptance, Chinese patent medicine tablets and granules produced by domestic pharmaceutical factories and solid preparations produced by food factories are generally coated with sugar; film Coating is a film formed by wrapping polymers on the outside of solid dosage forms. It can form a film layer with a thickness of 20-120 μm on the outside of tablets, granules and other dosage forms. This outer film can cover up various adverse effects. Odor, moisture-proof, light-proof, and air isolation ensure the stability of the product and prevent product potency from falling; in addition, because the tablet core has weak resistance to moisture and light, most Chinese patent medicine tablet cores require F...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K47/38A61K9/36
Inventor 彭桂华卢炜
Owner GUANGXI JIAJIN PHARMA