Handheld fluorescence microscope

Abstract

The invention provides a handheld fluorescence microscope. A local spectrum light source, a first optical filter, a second optical filter and an image sensing circuit are disposed in a shell of the handheld fluorescence microscope. The local spectrum light source is used for generating first light. The first optical filter is used for filtering the first light to generate second light. The second optical filter is used for filtering fluorescence generated by a sample irradiated by the second light so as to generate fourth light. The image sensing circuit is used for receiving the fourth light to generate fluorescent images. A light mask is disposed at one end of the shell and used for enclosing the sample so as to decrease or prevent light from entering the image sensing circuit from outside of the light mask. The second light irradiates an optical path of the sample, the optical path does not overlap with an optical path of the fluorescence which enters the second optical filter from the sample, and no splitter is disposed on the optical path of the fluorescence entering the second optical filter or the optical path of the fourth light entering the image sensing circuit. The handheld fluorescence microscope is capable of normally detecting fluorescent images in general environments.

Description

technical field [0001] The invention relates to microscopes, in particular to a hand-held fluorescence microscope. Background technique [0002] Many substances emit fluorescence at longer wavelengths after absorbing light of a specific wavelength. Therefore, in experiments and researches, it is possible to detect the presence or distribution of a certain substance in a sample by examining light of a specific wavelength. For example, when detecting DNA, antibodies, or other biological samples, the sample can be irradiated with light of a specific wavelength, and the fluorescence emitted by the sample can be observed with a fluorescence microscope to detect whether there is a substance to be detected in the sample. [0003] figure 1 It is a simplified structure diagram of the existing fluorescence microscope 100. The fluorescence microscope 100 includes an excitation light source 110, an excitation filter (excitation filter) 120, a dichroic mirror (dichroic mirror) 130, an ...

AI Technical Summary

Problems solved by technology

[0010] The above-mentioned factors not only make the manufacture of the existing fluorescence microscope 100 more complex, larger in size, and higher in cost, but also lead to the use limitation that the fluorescence microscope 100 must be operated in a specific environment (for example: a dark room) to perform normal functions.

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