Traditional Chinese medicine composition for curing tuberculous exadative pleurisy and preparation method thereof
A technology for exudative pleurisy and a composition, applied in the field of traditional Chinese medicine, can solve problems such as difficult to be cured completely, residual sequelae, pleural thickening, etc., reduce the probability of pleural hypertrophy or adhesion, alleviate pleural effusion adverse reactions, and symptoms of chest pain improved effect
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[0084] The present invention also provides a preparation method of the above-mentioned Chinese medicine composition, when the dosage form of the Chinese medicine composition is a tablet, specifically:
[0085] In the first step, mix yam, pearl ginseng, jujube, Mingdangshen, Schisandra chinensis, Polygonatum odoratum and Nansha ginseng, grind them, and add ethanol with an alcohol concentration of 65%~80% until the surface of the raw material medicine added in this step is completely submerged , stirred at a temperature of 30°C~40°C for 2h~3h, cooled to room temperature, placed in a percolator, and added an alcohol concentration of 12~15 times the mass of the raw material drug added in this step to 65 Soak in %~80% ethanol overnight, then percolate at a flow rate of 15ml~18ml per kilogram of medicinal materials per minute, collect 12 times the amount of percolation liquid of medicinal materials, recover ethanol, concentrate to 60°C to an extract with a relative density of 1.2~1.4, ...
Embodiment 1
[0094] The preparation of embodiment 1 granule 1
[0095] Mix 85g of yam, 65g of pearl ginseng, 55g of jujube, 35g of Mingdangshen, 55g of schisandra, 55g of Polygonatum odoratum and 50g of Nansha ginseng, grind them, add ethanol with an alcohol concentration of 75% until the surface of the above-mentioned added raw materials is completely submerged, Stir at a temperature of 40°C for 3 hours, cool to room temperature, place in a percolator, soak in 5.5kg of ethanol with an alcohol concentration of 75% overnight, then percolate at a flow rate of 15ml per minute per kg of medicinal materials, and collect 4.8 kg of percolation liquid, recovered ethanol, concentrated to extract at 60°C with a relative density of 1.2, then added 2 kg of water and stirred evenly, boiled to dissolve, refrigerated overnight, filtered to obtain the filtrate, and then added 4 times the volume of the filtrate The ethyl acetate extraction of 3 times, the combined ethyl acetate extract, concentrating under...
Embodiment 2
[0096] The preparation of embodiment 2 granules 2
[0097] Mix 87g of yam, 67g of pearl ginseng, 57g of jujube, 37g of Mingdangshen, 57g of Schisandra chinensis, 57g of Polygonatum odoratum and 52g of Nansha ginseng, pulverize, add ethanol with an alcohol concentration of 75% until the surface of the raw material drug added above is completely immersed, Stir at a temperature of 40°C for 3 hours, cool to room temperature, place in a percolator, soak in 5.5kg of ethanol with an alcohol concentration of 75% overnight, then percolate at a flow rate of 15ml per minute per kg of medicinal materials, and collect 4.9 kg of percolation liquid, recovered ethanol, concentrated to extract at 60°C with a relative density of 1.4, then added 2 kg of water and stirred evenly, boiled to dissolve, refrigerated overnight, filtered to obtain the filtrate, and then added 4 times the volume of the filtrate The ethyl acetate extraction of 3 times, combined ethyl acetate extract, concentrated under r...
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