Quartz crystal microbalance detecting device

Abstract

The invention discloses a quartz crystal microbalance detecting device which comprises a base, a sealing cover, a silicon gel gasket and a quartz wafer, wherein the quartz wafer is positioned inside a base groove; a quartz wafer groove is machined in the center of the bottom end of the quartz wafer; an upper electrode and a lower electrode are respectively arranged on the upper and lower sides of the quartz wafer groove; the upper and lower sides of the silicon gel gasket are respectively connected with the sealing cover and the base; the left and right ends of the quartz wafer groove are connected with the silicon gel gasket; a sample feeding port and a sample discharging port are both communicated with a central long through hole; the upper electrode is led out by an upper spring needle probe which penetrates through a third silicon gel through hole and an upper probe through hole in sequence; and the lower electrode is led out by a lower spring needle probe which penetrates through a lower probe through hole. The invention provides the quartz crystal microbalance detecting device; a flow cell in the device can be recycled with simple structure and stable performance; and moreover, the high-frequency miniaturization of a quartz crystal microbalance is realized, the mass-frequency sensitivity of the quartz crystal microbalance is improved, detection on small molecules or trace substances can be accomplished, and the minimum sample quantity of a desired object to be detected is small.

Description

Technical field [0001] The present invention relates to the technical field of sensing detection, in particular to a quartz crystal microbalance detection device. Background technique [0002] Quartz Crystal Microbalance (QCM) is a sensor that detects trace substances based on the change in the resonant frequency caused by the change in the quality of the surface of the wafer. It has the advantages of high sensitivity, simple structure, low cost, especially without sample marking. , Has been widely used as a detection and analysis tool in the fields of biology and chemistry. The quartz crystal microbalance is composed of AT-cut quartz wafers and metal excitation electrodes fixed on both sides of the wafer. The excitation electrode is generally derived from two socket pins welded on both sides of the chip, and connected to the test instrument or the resonance circuit. [0003] The combination of quartz crystal microbalance and flow injection analysis technology can realize real-ti...

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Problems solved by technology

[0007] The technical problem to be solved by the present invention is to provide a reusable and simple structure for the above-mentioned defects in the prior art that the quartz crystal microbalance flow cell cannot be reused, the requirements for assembly are very high, and the structure of the flow cell is too complicated. And the quartz crystal microbalance detection device of the flow cell with stable performance, the present invention also realizes the high-frequency miniaturization of the quartz crystal microbalance, improves its mass-frequency sensitivity, and can complete the detection of small molecules or trace substances , and the minimum sample size of the required substance to be detected is small

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