Diffusion cell device capable of adjusting capacity of receiving cell and effective diffusion area

A technology of diffusion area and receiving pool, which is applied in the direction of measuring devices, surface/boundary effects, instruments, etc., can solve the problems that the accuracy or sensitivity cannot be adjusted, so as to improve the accuracy of experimental data and work efficiency, shorten the experimental cycle, and avoid duplication The effect of sexual waste of resources

Active Publication Date: 2013-04-17
HARBIN MEDICAL UNIVERSITY
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  • Abstract
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Problems solved by technology

[0003] The object of the present invention is to provide a diffusion cell device capable of adjusting the effective diffusion area and the volu...

Method used

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  • Diffusion cell device capable of adjusting capacity of receiving cell and effective diffusion area
  • Diffusion cell device capable of adjusting capacity of receiving cell and effective diffusion area

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Embodiment Construction

[0015] see figure 1 and figure 2 , a diffusion cell device capable of adjusting the effective diffusion area and the volume of the receiving cell in the present invention, comprising a cylindrical supply cell 1, an upper specimen holding disc 2, a lower specimen holding disc 3, and a receiving cell 4 assembled together up and down in sequence , the lower end of the supply pool 1 is provided with an outer flange 11, and the upper end of the receiving pool 4 is provided with an outer flange 12 corresponding to the outer flange 11 of the supply pool 1, and is passed through a clamping device (conventional technology, not ) are docked with each other, and a receiving liquid inlet and outlet 7 is provided on the side of the receiving pool 4 . There are also more than one volume adjustment block (the number of which is determined by the size of the adjustment volume) set in the receiving tank 4, and its outer diameter matches the inner diameter of the receiving tank.

[0016] The...

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Abstract

The invention relates to a diffusion cell device capable of adjusting the capacity of receiving cell and effective diffusion area, comprising a cylindrical supply cell and a receptor cell. Each of the lower end of the supply cell and the upper end of the receptor ell is provided with an outer flange which corresponds to each other and is abutted mutually through a clamping device; the side of the receptor cell is provided with a receptor liquid port. The diffusion cell device is characterized by further comprising more than one capacity adjusting block arranged in the receptor cell, and the outer diameter of the capacity adjusting block is matched with the inner diameter of the receptor cell. The diffusion cell device has the advantages that the device fits for different sample types and meets different experiment requirements, repeated waste of resources is avoided as the size of a sample and the capacity of the receptor cell during testing, the experimental period is shortened, and the experiment data precision and the working efficiency are improved; and the diffusion cell device provides powerful hard conditions for development of new drugs.

Description

technical field [0001] The invention relates to a diffusion cell device capable of adjusting the effective diffusion area and the volume of the receiving cell, which is applied to the study of the static permeation membrane diffusion of drugs. Background technique [0002] China Patent Database (HowNet version) disclosed "an instrument for transdermal diffusion test", "in vitro transdermal diffusion tester", "bubble-free diffusion cell", "static diffusion cell for diffusion sampling system", "a test drug Six patents on the "experimental device that penetrates the skin" and "a detection device for drug transdermal release". Pool, water bath device and sampling port, the disadvantage is that for different sizes of specimens, and experiments with different precision or sensitivity requirements, it is necessary to customize products with different calibers and different volumes of receiving pools. If the sample size, precision or sensitivity need to be adjusted during the exper...

Claims

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Application Information

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IPC IPC(8): G01N13/04
Inventor 黄磊白建海崔浩马燕利
Owner HARBIN MEDICAL UNIVERSITY
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