Disinfectant for skin and mucosa

A disinfectant and skin technology, applied in the directions of disinfectants, biocides, local antibacterials, etc., can solve the problems of human and animal injury, environmental pollution, secondary poisoning, etc., and achieve improved effects, broad-spectrum killing, and bacteriostasis long time effect

Active Publication Date: 2013-09-04
柯 美华
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, traditional disinfectants usually have certain toxicity and residues, and long-term use will cause v...

Method used

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  • Disinfectant for skin and mucosa
  • Disinfectant for skin and mucosa

Examples

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Embodiment Construction

[0013] The invention is further illustrated by the following examples.

[0014] Experimental Materials.

[0015] One: Experimental strains.

[0016] 1. Escherichia coli Escherichia coli (8099).

[0017] 2. Staphylococcus aureus Staphylococcus aureus (ATCC6538).

[0018] 3. Aspergillus niger adenovirus.

[0019] Prepared into 1X108cfu / ml is the bacterial suspension.

[0020] Two: neutralizer and culture medium.

[0021] The neutralizing agent is a phosphate buffer containing 10g / L histidine, 3g / L lecithin, and 3% Tween-80. Through the neutralizer identification experiment, the selected neutralizer and its concentration are suitable. Medium: M-H nutrient agar.

[0022] Three: disinfectant (liquid) of the present invention.

[0023] Add 30g of Sophora flavescens, 30g of Fructus Cnidii, 30g of honeysuckle, 120g of licorice with acetone extract and 10,000 parts of water to make liquid A, and add the powder obtained by calcining mussels and other shellfish at a high temperat...

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Abstract

A disinfectant for skin and mucosa comprises ketone extracts of radix sophorae flavescentis, fructus cnidii, honeysuckles and liquorice; powder is obtained after shells are calcinated; double-chain quaternary ammonium salt is obtained; and the ketone extracts of the radix sophorae flavescentis, the fructus cnidii, the honeysuckles and the liquorice, the powder obtained after the shells are calcinated and the double-chain quaternary ammonium salt are mixed in an aqueous solution, and then the mixture is prepared into a needed dosage form. The disinfectant has the functions of quick acting, long acting and broad-spectrum killing of bacteria and viruses (such as influenza viruses), adenoviruses and malignant bacteria, the skin and mucosa tissues cannot be damaged, and no irritability or stimulation is caused to normal skin and mucosa tissues. The disinfectant can kill 99% of pathogenic microorganisms (viruses and bacteria) in 5 seconds, the continuous anti-bacteria time is long, the amount of quaternary ammonium salt in the disinfectant is 10-20% of that of quaternary ammonium salt in a conventional disinfectant, and the disinfectant is safer when used on the mucosa. Compared with a quaternary ammonium salt disinfectant for single application, the effect is improved by 10-15 times, and the product LD50 is improved by more than 5-10 times.

Description

technical field [0001] The invention relates to a disinfectant, which is suitable for sterilization and disinfection of normal skin, mucous membrane tissue, sanitation and epidemic prevention and the like. It can effectively kill various viruses (such as influenza virus), bacteria, harmful microorganisms, and is an effective sanitary defense against germ infection (such as influenza prevention). Background technique [0002] After experiencing "SARS", "bird flu", "hand, foot and mouth disease", "influenza A", "H7N9 influenza" and other epidemics, people's awareness of disinfection and sterilization has become stronger and stronger. With the development of health science Therefore, the disinfection and sterilization of patients and those in contact with patients has become an inevitable and necessary measure to cut off the transmission route. However, traditional disinfectants usually have certain toxicity and residues, and long-term use will cause varying degrees of damage ...

Claims

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Application Information

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IPC IPC(8): A61K36/489A01N65/20A01P1/00A61P31/02A61P31/04A61K35/56A61K35/618
Inventor 柯美华王峰张洪涛曹维骆卉妍黄清华柯华红
Owner 柯 美华
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