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Sustained-release solid ClO2 disinfectant and preparation method and application thereof

A disinfectant and slow-release technology, which is applied in the field of slow-release solid ClO2 disinfectant and its preparation, can solve the problems of short slow-release time and uneven slow-release, and achieve moderate density, stable extended release, and enhanced The effect of slow release effect

Inactive Publication Date: 2013-09-25
SHANGHAI HIGH SCHOOL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] It is also in two-component form, the liquid part is ClO 2 Stable liquid, the solid part contains activator, gelling agent, slow-release agent, when used, mix the two to form ClO 2 Solid gel, this method has a short sustained release time and uneven sustained release

Method used

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  • Sustained-release solid ClO2 disinfectant and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Add 25 g of isinglass powder and 30 mL of ClO with a concentration of 2.33 mg / mL in the Petri dish 2 The solution, 2 grams of β-cyclodextrin and 10 mL of distilled water are fully stirred on a magnetic stirrer, heated to 100°C, kept for 10s, and then put into the refrigerator at 0-4°C for 24 hours to form. The sustained-release effect of the sample prepared in this embodiment is very good, and the total sustained-release time of the sample can reach one month.

Embodiment 2

[0032] Add 25 g of isinglass powder and 30 mL of ClO with a concentration of 2.33 mg / mL in the Petri dish 2 The solution, 5 grams of β-cyclodextrin and 10 mL of distilled water were fully stirred on a magnetic stirrer, heated to 100°C, kept for 10 seconds, and then placed in the refrigerator for 24 hours to form.

Embodiment 3

[0034] Add 25 g of isinglass powder and 30 mL of ClO with a concentration of 2.33 mg / mL in the Petri dish 2 The solution, 10g of β-cyclodextrin and 10mL of distilled water are fully stirred on a magnetic stirrer, heated to 100°C, kept for 10s, and then the sample is placed in the refrigerator at 0-4°C for 24 hours to form.

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Abstract

The invention relates to a sterilization disinfectant, and particularly relates to a sustained-release solid ClO2 disinfectant and a preparation method and application thereof. The preparation method comprises the following steps of: uniformly stirring edible gelatin, a ClO2 solution, beta-cyclodextrin and distilled water; heating to 100-120 DEG C and keeping the temperature for 5-30 seconds; and then refrigerating the sample for 20-28 hours. The dosage ratio of the edible gelatin to the ClO2 to the beta-cyclodextrin to the distilled water is 1g:(0.1-5)mg:(0.01-0.8)g:(0.1-2)mL. According to the sustained-release solid ClO2 disinfectant, the beta-cyclodextrin and fish gelatin are mixed to prepare a solid; since the fish gelatin has good water containing property and moderate density and has a certain ClO2 sustained-release effect, the sustained release effect is enhanced by use of the double sustained release effects of the beta-cyclodextrin and the fish gelatin, and an aim of increasing the sustained release time and stabilizing the release quantity is achieved; and the preparation technology of the solid ClO2 disinfectant is simple and has high safety.

Description

technical field [0001] The invention relates to a bactericidal disinfectant, in particular to a slow-release solid ClO 2 Disinfectant and its preparation method and application. Background technique [0002] ClO 2 Disinfectant is the only high-efficiency disinfectant among internationally recognized chlorine-containing disinfectants. It can kill all microorganisms, including bacterial propagules, bacterial spores, fungi, mycobacteria and viruses, etc., and these bacteria will not produce drug resistance. Chlorine dioxide has a strong ability to adsorb and penetrate microbial cell walls, effectively oxidize enzymes containing sulfhydryl groups in cells, and rapidly inhibit the synthesis of microbial proteins to destroy microorganisms. It has the advantages of good sterilization effect, high safety, wide applicable pH, low toxicity, and less potential carcinogens (halogenated hydrocarbons), so it is listed as A1 grade disinfectant by the World Health Organization. Widely u...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N25/10A01N59/00A01P1/00
Inventor 丁蕴峰
Owner SHANGHAI HIGH SCHOOL
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