A detection method for water-soluble sugar content in mainstream smoke
A technology for water-soluble sugar and detection method, which is applied in measuring devices, instruments, scientific instruments, etc., can solve the problems of inability to accurately measure water-soluble sugar content analysis, lack of guiding significance, etc., and achieve low detection limit and good repeatability. Effect
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Embodiment 1
[0049] Embodiment 1 The influence of extraction method on result :
[0050] Prepare a sample to be tested according to the treatment method recorded in S1., use ultrasonic extraction and mechanical vibration extraction, and then perform detection. It can be seen from Table 3 that for the test sample, the extraction amount of the ultrasonic extraction method is more than 16% more than that of the vibration method. The possible reason is that the sugar trapped inside the Cambridge filter is more easily extracted by the solution under the action of ultrasonic waves, while mechanical oscillation cannot fully extract the water-soluble sugar inside the Cambridge filter.
[0051] Table 3: Comparison of ultrasonic extraction and vibration extraction (μg / cigarette)
[0052] sugar shaking extraction ultrasonic extraction Arabic candy 2.36 2.93 Galactose 0.34 0.51 glucose 26.12 34.30 Xylose 1.93 2.24 Mannose 4.53 5.37 fructose 53.5...
Embodiment 2
[0053] Example 2 Standard curve linearity, detection limit:
[0054] Quantification by external standard method. With the concentration (μg / mL) as the abscissa x and the peak area as the ordinate y, perform linear regression to obtain the linear regression equation and correlation coefficient. The results showed that the linearity of the method was good, and the correlation coefficients were all greater than 0.999 (Table 4). The signal-to-noise ratio (S / N) was used as the detection limit of the above detection method. The detection limit of the method is lower than 10 ng / mL, and the sensitivity is high.
[0055] Table 4 The linear equation, correlation coefficient and detection limit of the test method
[0056] sugar linear equation correlation coefficient LOD (μg / L) LOQ (μg / L) Arabic candy y = 0.0051x-0.0260 1.0000 2.47 8.23 Galactose y = 0.0045x-0.0045 0.9998 4.10 13.68 glucose y = 0.0046x +0.3164 0.9993 3.31 11.04 Xy...
Embodiment 3
[0057] The precision of embodiment 3 method:
[0058] According to the sample processing method described in S1., 5 copies of the same sample were processed in parallel and measured on the same day to investigate the intraday precision of the method (Table 5). The same sample was processed and measured 4 times in parallel at an interval of 1 day or more within 5 days to investigate the inter-day precision of the method (Table 6). The intra-day and inter-day precision results of the method were expressed as the relative standard deviation of the sugar content value, which were between 2.46% ~ 4.91% and 2.30% ~ 6.82%, respectively, indicating that the method had good repeatability.
[0059] Table 5 Intraday precision of the method
[0060]
[0061] Table 6 Interday precision of the method
[0062]
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