Precise machining method for capillary tube for biodegradable magnesium alloy intravascular stent

Abstract

The invention discloses a precise machining method for a capillary tube for a biodegradable magnesium alloy intravascular stent. The method comprises the following steps of: step 1, performing stress relief annealing and machining on a magnesium alloy extrusion bar to obtain a tube blank; step 2, extruding the tube blank to obtain a seamless extrusion tube blank, and performing stress relief annealing; step 3, performing multi-pass rolling and annealing on the annealed seamless extrusion tube blank to obtain a thin tube blank; and step 4, performing multi-pass drawing and annealing on the thin tube blank to obtain the capillary tube for the biodegradable magnesium alloy intravascular stent. The capillary tube produced by the method disclosed by the invention is accurate in dimension (a wall thickness error is not greater than 5%), can be more than 1 metre long, is high in surface quality, uniform in matrix structure, excellent in mechanical property, low in machining cost and high in machining efficiency, and can be subjected to industrialized batch production.

Description

technical field

[0001] The invention relates to the field of biomaterial processing, in particular to a precision processing method for capillary tubes used in degradable magnesium alloy intravascular stents. Background technique

[0002] In the field of cardiovascular disease treatment, interventional endovascular stent therapy has become the most important means. At present, most clinical interventional stents are mainly made of non-degradable metal materials, such as stainless steel, nickel-titanium alloy or cobalt-chromium alloy, and stents made of degradable magnesium alloy materials have not yet entered clinical application. These permanent stents will have many negative effects on the human body, such as intimal hyperplasia and local inflammation. Magnesium alloy has good biocompatibility and can be gradually degraded and absorbed in the body, showing its great application potential as a degradable biomaterial. However, the plasticity of magnesium alloy at room temp...

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